SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 12 GLY A 211
GLY A 213
ILE A  10
GLU A 116
PHE A 115
 None
 1.01A 1nv8B-1bg5A:
undetectable		 1nv8B-1bg5A:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 11 ARG A  73
ILE A  72
HIS A  79
MET A  81
TYR A  23
 None
 1.19A 2azyA-1bg5A:
undetectable		 2azyA-1bg5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 5 TYR A 104
ALA A 110
ALA A 158
MET A 129
 None
 1.10A 3d91A-1bg5A:
undetectable		 3d91A-1bg5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		3 / 3 ASP A  77
ARG A  73
ALA A  76
 None
 0.79A 3mbgC-1bg5A:
0.0		 3mbgC-1bg5A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 5 SER A 226
ARG A 224
PRO A 223
VAL A 222
 None
 1.01A 3sufC-1bg5A:
undetectable		 3sufC-1bg5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 9 LEU A 126
ALA A 158
ASP A 157
LEU A 100
ILE A 102
 None
 1.41A 3wsjA-1bg5A:
undetectable		 3wsjA-1bg5A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 9 LEU A   5
GLY A   6
ILE A  75
VAL A  14
THR A  17
 None
 1.29A 4x3mA-1bg5A:
undetectable		 4x3mA-1bg5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 ILE A  92
LYS A  87
GLY A  84
GLY A  83
 None
 0.74A 5a06A-1bg5A:
undetectable		 5a06A-1bg5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 ILE A  92
LYS A  87
GLY A  84
GLY A  83
 None
 0.74A 5a06B-1bg5A:
undetectable		 5a06B-1bg5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 ILE A  92
LYS A  87
GLY A  84
GLY A  83
 None
 0.73A 5a06C-1bg5A:
undetectable		 5a06C-1bg5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 ILE A  92
LYS A  87
GLY A  84
GLY A  83
 None
 0.76A 5a06E-1bg5A:
undetectable		 5a06E-1bg5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 ILE A  92
LYS A  87
GLY A  84
GLY A  83
 None
 0.74A 5a06F-1bg5A:
undetectable		 5a06F-1bg5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 VAL A 106
SER A 107
ALA A 110
GLY A 211
 None
 0.89A 5fpdA-1bg5A:
undetectable		 5fpdA-1bg5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 7 VAL A 106
SER A 107
ALA A 110
GLY A 211
 None
 0.89A 5fpdB-1bg5A:
undetectable		 5fpdB-1bg5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 8 LEU A  21
PRO A   3
ILE A  75
LEU A  20
 None
 0.73A 5g48A-1bg5A:
undetectable		 5g48A-1bg5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 12 LEU A 137
ASP A 152
ALA A 158
LEU A 176
ARG A 136
 None
 1.15A 6ew0F-1bg5A:
undetectable		 6ew0F-1bg5A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		5 / 12 LEU A 170
ALA A 158
LEU A 143
LEU A 130
LEU A 176
 None
 0.90A 6f6iA-1bg5A:
undetectable
6f6iB-1bg5A:
undetectable		 6f6iA-1bg5A:
16.67
6f6iB-1bg5A:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE
(Rattus
norvegicus) 		4 / 5 GLY A  12
SER A 107
TYR A 111
GLN A 204
 None
 1.15A 6ji6A-1bg5A:
30.7		 6ji6A-1bg5A:
87.80