SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IIU_A_RTLA176_0 (PLASMA RETINOL-BINDING PROTEIN)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 11	LEU A 139 LEU A 56 ALA A 48 ALA A 60 LEU A 23	None	1.39A	1iiuA-1bg6A: undetectable	1iiuA-1bg6A: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ARM_A_OINA401_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	HIS A 202 ASP A 297 TYR A 293 PRO A 286	None	1.03A	2armA-1bg6A: undetectable	2armA-1bg6A: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_C_VIAC903_2 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	ASN A 277 ILE A 226 MET A 201	None	0.65A	2h42C-1bg6A: 0.0	2h42C-1bg6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	LEU A 305 PRO A 304 LEU A 308	None	0.61A	2po5B-1bg6A: 2.6	2po5B-1bg6A: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQC_A_AG2A671_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC))	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	MET A 159 GLN A 182 LEU A 139 LEU A 80	None	0.87A	2qqcB-1bg6A: 0.0 2qqcC-1bg6A: 0.0	2qqcB-1bg6A: 18.47 2qqcC-1bg6A: 11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQC_A_AG2A672_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC))	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	LEU A 139 LEU A 80 MET A 159 GLN A 182	None	0.90A	2qqcA-1bg6A: 0.0 2qqcF-1bg6A: 0.0	2qqcA-1bg6A: 11.90 2qqcF-1bg6A: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQC_I_AG2I671_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC))	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	LEU A 139 LEU A 80 MET A 159 GLN A 182	None	0.90A	2qqcG-1bg6A: 0.0 2qqcJ-1bg6A: 0.0	2qqcG-1bg6A: 11.90 2qqcJ-1bg6A: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQC_I_AG2I672_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC))	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	LEU A 139 LEU A 80 MET A 159 GLN A 182	None	0.89A	2qqcI-1bg6A: 0.0 2qqcL-1bg6A: 0.0	2qqcI-1bg6A: 11.90 2qqcL-1bg6A: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_H_CPFH1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	ARG A 339 GLU A 117 SER A 327	None	0.84A	2xctD-1bg6A: 2.1	2xctD-1bg6A: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	LEU A 107 ILE A 105 ILE A 79 ILE A 81 PHE A 118	None	0.90A	2ygoA-1bg6A: undetectable	2ygoA-1bg6A: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZTH_A_SAMA305_0 (CATECHOL O-METHYLTRANSFERASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	VAL A 30 GLY A 16 TYR A 7 SER A 144 HIS A 17	None	1.43A	2zthA-1bg6A: 5.9	2zthA-1bg6A: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOD_C_RFPC2002_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	GLN A 149 ALA A 60 PHE A 140 GLY A 148 LEU A 12	None	1.42A	3aodC-1bg6A: 0.0	3aodC-1bg6A: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DQT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.37A	3dqtA-1bg6A: 0.0 3dqtB-1bg6A: 0.0	3dqtA-1bg6A: 23.79 3dqtB-1bg6A: 23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E23_A_SAMA221_1 (UNCHARACTERIZED PROTEIN RPA2492)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	TYR A 259 ASP A 238 HIS A 202	None	0.79A	3e23A-1bg6A: 4.5	3e23A-1bg6A: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_B_TRPB1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 8	GLY A 15 VAL A 82 VAL A 150 VAL A 152	None	0.80A	3fi0B-1bg6A: undetectable	3fi0B-1bg6A: 24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 11	MET A 138 LEU A 180 LEU A 80 PHE A 140 THR A 135	None	1.30A	3jw5A-1bg6A: undetectable	3jw5A-1bg6A: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 11	MET A 138 LEU A 180 LEU A 80 VAL A 82 THR A 135	None	1.26A	3jw5A-1bg6A: undetectable	3jw5A-1bg6A: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5T_A_H4BA600_1 (NITRIC OXIDE SYNTHASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	SER A 356 VAL A 358 PHE A 248 GLU A 359	None	1.36A	3n5tA-1bg6A: 0.0 3n5tB-1bg6A: 0.0	3n5tA-1bg6A: 22.81 3n5tB-1bg6A: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 6	HIS A 17 PRO A 62 LEU A 65 ASP A 34	None	1.10A	3oi8A-1bg6A: undetectable	3oi8A-1bg6A: 16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROD_D_NCAD302_0 (NICOTINAMIDE N-METHYLTRANSFERASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	TYR A 222 ASP A 238 ALA A 234 TYR A 259	None	1.21A	3rodD-1bg6A: 4.4	3rodD-1bg6A: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3M_A_DLUA398_1 (PFV INTEGRASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 8	ASP A 34 GLY A 16 PRO A 147 ARG A 143	None	0.87A	3s3mA-1bg6A: undetectable	3s3mA-1bg6A: 23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKA_A_SAMA400_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	GLY A 114 HIS A 88 PHE A 19 SER A 136 MET A 159	None	1.32A	3tkaA-1bg6A: 5.6	3tkaA-1bg6A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_A_AZMA229_1 (CARBONIC ANHYDRASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 10	CYH A 142 VAL A 150 GLY A 16 ALA A 18 ALA A 20	None	1.22A	3ucjA-1bg6A: undetectable	3ucjA-1bg6A: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5J_B_H4BB502_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.37A	4k5jA-1bg6A: 0.0 4k5jB-1bg6A: 0.0	4k5jA-1bg6A: 22.86 4k5jB-1bg6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2V_A_BZ1A302_2 (CARBONIC ANHYDRASE 2)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	HIS A 88 VAL A 73 LEU A 10	None	0.76A	4m2vA-1bg6A: 0.0	4m2vA-1bg6A: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD5_A_GEOA501_1 (NUPC FAMILY PROTEIN)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	GLY A 70 ALA A 72 LEU A 10 SER A 100 ILE A 99	None	1.15A	4pd5A-1bg6A: 0.0	4pd5A-1bg6A: 25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 8	ALA A 60 ALA A 21 ILE A 49 ALA A 8 LEU A 12	None	1.24A	4v1fA-1bg6A: undetectable 4v1fB-1bg6A: undetectable	4v1fA-1bg6A: 15.38 4v1fB-1bg6A: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 4	TYR A 183 THR A 135 GLY A 133 LEU A 104	None	1.09A	4w5nA-1bg6A: 1.6	4w5nA-1bg6A: 17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_B_RTZB602_2 (CYTOCHROME P450 2D6)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	GLU A 134 ILE A 354 ALA A 166	None	0.66A	4wnwB-1bg6A: 0.0	4wnwB-1bg6A: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADL_B_H4BB600_1 (ENDOTHELIAL NITRIC OXIDE SYNTHASE)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.37A	5adlA-1bg6A: 0.0 5adlB-1bg6A: 0.0	5adlA-1bg6A: 22.86 5adlB-1bg6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FJ3_B_H4BB600_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.39A	5fj3A-1bg6A: 0.0 5fj3B-1bg6A: 0.0	5fj3A-1bg6A: 22.86 5fj3B-1bg6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_B_AG2B501_1 (ARGININE/AGMATINE ANTIPORTER)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 6	ILE A 50 GLY A 15 ASN A 14 ILE A 49	None	0.98A	5j4nB-1bg6A: 0.0	5j4nB-1bg6A: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J6H_A_NCAA402_0 (H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, Q10 ALPHA CHAIN)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	PRO A 147 ARG A 146 GLU A 42	None	0.85A	5j6hA-1bg6A: 0.0	5j6hA-1bg6A: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TL8_A_X2NA502_1 (PROTEIN CYP51)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 12	ALA A 32 ALA A 185 ALA A 169 THR A 131 LEU A 104	None	1.17A	5tl8A-1bg6A: undetectable	5tl8A-1bg6A: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV7_B_H4BB502_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.39A	5vv7A-1bg6A: 0.0 5vv7B-1bg6A: 0.0	5vv7A-1bg6A: 22.86 5vv7B-1bg6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VVN_B_H4BB502_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	PHE A 248 GLU A 359 SER A 356 VAL A 358	None	1.35A	5vvnA-1bg6A: 0.0 5vvnB-1bg6A: 0.0	5vvnA-1bg6A: 22.86 5vvnB-1bg6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7B_B_PA1B204_1 (ACYLOXYACYL HYDROLASE SMALL SUBUNIT ACYLOXYACYL HYDROLASE LARGE SUBUNIT)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	3 / 3	GLY A 13 ASN A 14 ARG A 292	None	0.67A	5w7bD-1bg6A: 3.3	5w7bD-1bg6A: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X2T_I_PEMI202_1 (HEMOGLOBIN SUBUNIT ALPHA HEMOGLOBIN SUBUNIT BETA)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 8	PRO A 253 THR A 192 THR A 195 ALA A 158	None	1.00A	5x2tI-1bg6A: undetectable 5x2tJ-1bg6A: undetectable 5x2tK-1bg6A: undetectable 5x2tL-1bg6A: undetectable	5x2tI-1bg6A: 17.66 5x2tJ-1bg6A: 22.55 5x2tK-1bg6A: 17.66 5x2tL-1bg6A: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV6_B_H4BB501_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	SER A 356 VAL A 358 PHE A 248 GLU A 359	None	1.44A	6av6A-1bg6A: 0.0 6av6B-1bg6A: 0.0	6av6A-1bg6A: 14.62 6av6B-1bg6A: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV7_A_H4BA502_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	4 / 7	SER A 356 VAL A 358 PHE A 248 GLU A 359	None	1.42A	6av7A-1bg6A: 0.0 6av7B-1bg6A: 0.0	6av7A-1bg6A: 14.62 6av7B-1bg6A: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G9B_A_IXXA609_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN ENVELOPE GLYCOPROTEIN)	1bg6	N-(1-D-CARBOXYLETHYL )-L-NORVALINE DEHYDROGENASE (Arthrobacter sp. 1C)	5 / 7	ILE A 244 LEU A 308 VAL A 358 LEU A 190 LEU A 250	None	1.08A	6g9bA-1bg6A: 0.0 6g9bB-1bg6A: 0.0	6g9bA-1bg6A: 13.45 6g9bB-1bg6A: 13.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IIU_A_RTLA176_0","PLASMA RETINOL-BINDING PROTEIN","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"LEU A 139;LEU A  56;ALA A  48;ALA A  60;LEU A  23","None","1.39A","1iiuA-1bg6A:undetectable","1iiuA-1bg6A:19.94"],["2ARM_A_OINA401_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"HIS A 202;ASP A 297;TYR A 293;PRO A 286","None","1.03A","2armA-1bg6A:undetectable","2armA-1bg6A:17.50"],["2H42_C_VIAC903_2","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"ASN A 277;ILE A 226;MET A 201","None","0.65A","2h42C-1bg6A:0.0","2h42C-1bg6A:21.85"],["2PO5_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"LEU A 305;PRO A 304;LEU A 308","None","0.61A","2po5B-1bg6A:2.6","2po5B-1bg6A:23.72"],["2QQC_A_AG2A671_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC)","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"MET A 159;GLN A 182;LEU A 139;LEU A  80","None","0.87A","2qqcB-1bg6A:0.0;2qqcC-1bg6A:0.0","2qqcB-1bg6A:18.47;2qqcC-1bg6A:11.90"],["2QQC_A_AG2A672_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC)","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"LEU A 139;LEU A  80;MET A 159;GLN A 182","None","0.90A","2qqcA-1bg6A:0.0;2qqcF-1bg6A:0.0","2qqcA-1bg6A:11.90;2qqcF-1bg6A:18.47"],["2QQC_I_AG2I671_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC)","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"LEU A 139;LEU A  80;MET A 159;GLN A 182","None","0.90A","2qqcG-1bg6A:0.0;2qqcJ-1bg6A:0.0","2qqcG-1bg6A:11.90;2qqcJ-1bg6A:18.47"],["2QQC_I_AG2I672_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC)","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"LEU A 139;LEU A  80;MET A 159;GLN A 182","None","0.89A","2qqcI-1bg6A:0.0;2qqcL-1bg6A:0.0","2qqcI-1bg6A:11.90;2qqcL-1bg6A:18.47"],["2XCT_H_CPFH1020_1","DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"ARG A 339;GLU A 117;SER A 327","None","0.84A","2xctD-1bg6A:2.1","2xctD-1bg6A:19.94"],["2YGO_A_PCFA1213_0","WNT INHIBITORY FACTOR 1","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"LEU A 107;ILE A 105;ILE A  79;ILE A  81;PHE A 118","None","0.90A","2ygoA-1bg6A:undetectable","2ygoA-1bg6A:19.78"],["2ZTH_A_SAMA305_0","CATECHOL O-METHYLTRANSFERASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"VAL A  30;GLY A  16;TYR A   7;SER A 144;HIS A  17","None","1.43A","2zthA-1bg6A:5.9","2zthA-1bg6A:21.58"],["3AOD_C_RFPC2002_1","ACRIFLAVINE RESISTANCE PROTEIN B","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"GLN A 149;ALA A  60;PHE A 140;GLY A 148;LEU A  12","None","1.42A","3aodC-1bg6A:0.0","3aodC-1bg6A:17.30"],["3DQT_B_H4BB760_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.37A","3dqtA-1bg6A:0.0;3dqtB-1bg6A:0.0","3dqtA-1bg6A:23.79;3dqtB-1bg6A:23.79"],["3E23_A_SAMA221_1","UNCHARACTERIZED PROTEIN RPA2492","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"TYR A 259;ASP A 238;HIS A 202","None","0.79A","3e23A-1bg6A:4.5","3e23A-1bg6A:22.16"],["3FI0_B_TRPB1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"GLY A  15;VAL A  82;VAL A 150;VAL A 152","None","0.80A","3fi0B-1bg6A:undetectable","3fi0B-1bg6A:24.01"],["3JW5_A_TOPA208_1","DIHYDROFOLATE REDUCTASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"MET A 138;LEU A 180;LEU A  80;PHE A 140;THR A 135","None","1.30A","3jw5A-1bg6A:undetectable","3jw5A-1bg6A:16.53"],["3JW5_A_TOPA208_1","DIHYDROFOLATE REDUCTASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"MET A 138;LEU A 180;LEU A  80;VAL A  82;THR A 135","None","1.26A","3jw5A-1bg6A:undetectable","3jw5A-1bg6A:16.53"],["3N5T_A_H4BA600_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"SER A 356;VAL A 358;PHE A 248;GLU A 359","None","1.36A","3n5tA-1bg6A:0.0;3n5tB-1bg6A:0.0","3n5tA-1bg6A:22.81;3n5tB-1bg6A:22.81"],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"HIS A  17;PRO A  62;LEU A  65;ASP A  34","None","1.10A","3oi8A-1bg6A:undetectable","3oi8A-1bg6A:16.44"],["3ROD_D_NCAD302_0","NICOTINAMIDE N-METHYLTRANSFERASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"TYR A 222;ASP A 238;ALA A 234;TYR A 259","None","1.21A","3rodD-1bg6A:4.4","3rodD-1bg6A:21.51"],["3S3M_A_DLUA398_1","PFV INTEGRASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"ASP A  34;GLY A  16;PRO A 147;ARG A 143","None","0.87A","3s3mA-1bg6A:undetectable","3s3mA-1bg6A:23.96"],["3TKA_A_SAMA400_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"GLY A 114;HIS A  88;PHE A  19;SER A 136;MET A 159","None","1.32A","3tkaA-1bg6A:5.6","3tkaA-1bg6A:23.56"],["3UCJ_A_AZMA229_1","CARBONIC ANHYDRASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"CYH A 142;VAL A 150;GLY A  16;ALA A  18;ALA A  20","None","1.22A","3ucjA-1bg6A:undetectable","3ucjA-1bg6A:23.74"],["4K5J_B_H4BB502_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.37A","4k5jA-1bg6A:0.0;4k5jB-1bg6A:0.0","4k5jA-1bg6A:22.86;4k5jB-1bg6A:22.86"],["4M2V_A_BZ1A302_2","CARBONIC ANHYDRASE 2","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"HIS A  88;VAL A  73;LEU A  10","None","0.76A","4m2vA-1bg6A:0.0","4m2vA-1bg6A:21.37"],["4PD5_A_GEOA501_1","NUPC FAMILY PROTEIN","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"GLY A  70;ALA A  72;LEU A  10;SER A 100;ILE A  99","None","1.15A","4pd5A-1bg6A:0.0","4pd5A-1bg6A:25.29"],["4V1F_B_BQ1B1087_0","F0F1 ATP SYNTHASE SUBUNIT C","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"ALA A  60;ALA A  21;ILE A  49;ALA A   8;LEU A  12","None","1.24A","4v1fA-1bg6A:undetectable;4v1fB-1bg6A:undetectable","4v1fA-1bg6A:15.38;4v1fB-1bg6A:15.38"],["4W5N_A_IPHA903_0","PROTEIN ARGONAUTE-2","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"TYR A 183;THR A 135;GLY A 133;LEU A 104","None","1.09A","4w5nA-1bg6A:1.6","4w5nA-1bg6A:17.61"],["4WNW_B_RTZB602_2","CYTOCHROME P450 2D6","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"GLU A 134;ILE A 354;ALA A 166","None","0.66A","4wnwB-1bg6A:0.0","4wnwB-1bg6A:21.41"],["5ADL_B_H4BB600_1","ENDOTHELIAL NITRIC OXIDE SYNTHASE;ENDOTHELIAL NITRIC OXIDE SYNTHASE","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.37A","5adlA-1bg6A:0.0;5adlB-1bg6A:0.0","5adlA-1bg6A:22.86;5adlB-1bg6A:22.86"],["5FJ3_B_H4BB600_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.39A","5fj3A-1bg6A:0.0;5fj3B-1bg6A:0.0","5fj3A-1bg6A:22.86;5fj3B-1bg6A:22.86"],["5J4N_B_AG2B501_1","ARGININE\/AGMATINE ANTIPORTER","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"ILE A  50;GLY A  15;ASN A  14;ILE A  49","None","0.98A","5j4nB-1bg6A:0.0","5j4nB-1bg6A:23.89"],["5J6H_A_NCAA402_0","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, Q10 ALPHA CHAIN","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"PRO A 147;ARG A 146;GLU A  42","None","0.85A","5j6hA-1bg6A:0.0","5j6hA-1bg6A:21.04"],["5TL8_A_X2NA502_1","PROTEIN CYP51","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"ALA A  32;ALA A 185;ALA A 169;THR A 131;LEU A 104","None","1.17A","5tl8A-1bg6A:undetectable","5tl8A-1bg6A:20.68"],["5VV7_B_H4BB502_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.39A","5vv7A-1bg6A:0.0;5vv7B-1bg6A:0.0","5vv7A-1bg6A:22.86;5vv7B-1bg6A:22.86"],["5VVN_B_H4BB502_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PHE A 248;GLU A 359;SER A 356;VAL A 358","None","1.35A","5vvnA-1bg6A:0.0;5vvnB-1bg6A:0.0","5vvnA-1bg6A:22.86;5vvnB-1bg6A:22.86"],["5W7B_B_PA1B204_1","ACYLOXYACYL HYDROLASE SMALL SUBUNIT;ACYLOXYACYL HYDROLASE LARGE SUBUNIT","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",3,"GLY A  13;ASN A  14;ARG A 292","None","0.67A","5w7bD-1bg6A:3.3","5w7bD-1bg6A:11.93"],["5X2T_I_PEMI202_1","HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA;HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"PRO A 253;THR A 192;THR A 195;ALA A 158","None","1.00A","5x2tI-1bg6A:undetectable;5x2tJ-1bg6A:undetectable;5x2tK-1bg6A:undetectable;5x2tL-1bg6A:undetectable","5x2tI-1bg6A:17.66;5x2tJ-1bg6A:22.55;5x2tK-1bg6A:17.66;5x2tL-1bg6A:22.55"],["6AV6_B_H4BB501_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"SER A 356;VAL A 358;PHE A 248;GLU A 359","None","1.44A","6av6A-1bg6A:0.0;6av6B-1bg6A:0.0","6av6A-1bg6A:14.62;6av6B-1bg6A:14.62"],["6AV7_A_H4BA502_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",4,"SER A 356;VAL A 358;PHE A 248;GLU A 359","None","1.42A","6av7A-1bg6A:0.0;6av7B-1bg6A:0.0","6av7A-1bg6A:14.62;6av7B-1bg6A:14.62"],["6G9B_A_IXXA609_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN;ENVELOPE GLYCOPROTEIN","1bg6","N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE","Arthrobacter sp. 1C",5,"ILE A 244;LEU A 308;VAL A 358;LEU A 190;LEU A 250","None","1.08A","6g9bA-1bg6A:0.0;6g9bB-1bg6A:0.0","6g9bA-1bg6A:13.45;6g9bB-1bg6A:13.02"]]