SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		4 / 7 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 1.06A 2vcvA-1bgcA:
undetectable		 2vcvA-1bgcA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		4 / 7 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 1.00A 2vcvL-1bgcA:
2.2		 2vcvL-1bgcA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		4 / 6 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.88A 3bjwE-1bgcA:
undetectable		 3bjwE-1bgcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		4 / 7 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.92A 3bjwF-1bgcA:
undetectable		 3bjwF-1bgcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		4 / 7 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 0.91A 3bjwH-1bgcA:
undetectable		 3bjwH-1bgcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		5 / 12 LEU A  83
PHE A 114
LEU A  15
LEU A  10
LEU A  70
 None
 1.22A 5iepA-1bgcA:
undetectable		 5iepA-1bgcA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		5 / 12 LEU A 153
ILE A  96
LEU A  93
HIS A  40
LEU A  42
 None
 1.26A 5toaB-1bgcA:
undetectable		 5toaB-1bgcA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Bos
taurus) 		5 / 12 LEU A 172
LEU A 169
GLY A  74
GLY A 126
PRO A  11
 None
 1.05A 6ce2B-1bgcA:
undetectable		 6ce2B-1bgcA:
20.12