SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bgx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1bgx TP7 MAB
(Mus
musculus) 		4 / 8 ALA H  33
ASN H  35
TRP H  47
TYR H  50
 None
 0.83A 1rukH-1bgxH:
23.0
1rukL-1bgxH:
11.0		 1rukH-1bgxH:
86.76
1rukL-1bgxH:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1bgx TP7 MAB
(Mus
musculus) 		3 / 3 PRO H   9
LEU H 111
ARG H  38
 None
 0.82A 3aqiA-1bgxH:
undetectable		 3aqiA-1bgxH:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1bgx TP7 MAB
(Mus
musculus) 		3 / 3 PRO H   9
LEU H 111
ARG H  38
 None
 0.66A 3aqiB-1bgxH:
undetectable		 3aqiB-1bgxH:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 1bgx TP7 MAB
(Mus
musculus) 		5 / 11 LEU H  20
GLY H  10
LEU H  11
ALA H  88
ASP H  86
 None
 1.19A 4wnuC-1bgxH:
undetectable		 4wnuC-1bgxH:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1bgx TP7 MAB
(Mus
musculus) 		4 / 5 PRO H  41
GLY H  42
ASN H  43
LYS H  44
 None
 1.15A 5x23A-1bgxH:
0.0		 5x23A-1bgxH:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1bgx TP7 MAB
(Mus
musculus) 		3 / 3 SER H 199
ALA H 194
VAL H 193
 None
 0.53A 5xiwC-1bgxH:
undetectable		 5xiwC-1bgxH:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1bgx TP7 MAB
(Mus
musculus) 		4 / 5 GLU H 144
PHE H 142
HIS H 195
THR H 112
 None
 1.38A 6b58A-1bgxH:
0.0		 6b58A-1bgxH:
17.16