SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 11 GLY A  65
HIS A  64
HIS A  67
ILE A  30
GLY A 219
 None
1BH  A 300 ( 3.0A)
None
None
1BH  A 300 (-3.5A)
 1.13A 1gtfS-1bh6A:
undetectable
1gtfT-1bh6A:
undetectable		 1gtfS-1bh6A:
12.69
1gtfT-1bh6A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 9 ALA A  69
VAL A  44
GLY A  29
ILE A  31
ILE A  35
 None
 1.11A 1hpvB-1bh6A:
undetectable		 1hpvB-1bh6A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 6 VAL A 192
GLU A 195
LEU A 196
PHE A 261
 None
 1.14A 1s8fB-1bh6A:
0.9		 1s8fB-1bh6A:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 11 GLY A  65
HIS A  64
HIS A  67
ILE A  30
GLY A 219
 None
1BH  A 300 ( 3.0A)
None
None
1BH  A 300 (-3.5A)
 1.13A 1utdS-1bh6A:
undetectable
1utdT-1bh6A:
undetectable		 1utdS-1bh6A:
12.69
1utdT-1bh6A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 9 ALA A 151
ALA A 153
SER A 190
SER A 224
ALA A 223
 None
 1.25A 2vh3A-1bh6A:
undetectable		 2vh3A-1bh6A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 7 TYR A 171
SER A 173
GLN A 137
ILE A 111
 None
 1.08A 2xz5A-1bh6A:
undetectable
2xz5B-1bh6A:
0.0		 2xz5A-1bh6A:
21.62
2xz5B-1bh6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 8 TYR A 171
SER A 173
GLN A 137
ILE A 111
 None
 1.05A 2xz5B-1bh6A:
0.0
2xz5E-1bh6A:
0.0		 2xz5B-1bh6A:
21.62
2xz5E-1bh6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 THR A   3
VAL A  81
GLY A  80
LYS A   1
 None
None
CA  A 501 ( 4.3A)
None
 1.08A 3elzA-1bh6A:
0.0		 3elzA-1bh6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 GLY A  70
GLY A  83
ILE A  35
ASP A  41
LEU A  42
 None
None
None
CA  A 501 (-2.2A)
None
 1.03A 3ihtA-1bh6A:
3.1		 3ihtA-1bh6A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.39A 3ijxB-1bh6A:
undetectable
3ijxD-1bh6A:
undetectable		 3ijxB-1bh6A:
22.45
3ijxD-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.38A 3ik6B-1bh6A:
0.0
3ik6E-1bh6A:
0.0		 3ik6B-1bh6A:
22.45
3ik6E-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 LEU A 126
ILE A  31
SER A 109
SER A 105
GLY A 110
 1BH  A 300 (-4.0A)
None
None
None
None
 1.34A 3iluB-1bh6A:
0.0
3iluE-1bh6A:
0.0		 3iluB-1bh6A:
22.45
3iluE-1bh6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.05A 3ln1A-1bh6A:
undetectable		 3ln1A-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.04A 3ln1B-1bh6A:
undetectable		 3ln1B-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.04A 3ln1C-1bh6A:
0.0		 3ln1C-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.03A 3ln1D-1bh6A:
undetectable		 3ln1D-1bh6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 ALA A 176
LEU A 250
ALA A 231
VAL A  84
THR A  71
 NA  A 502 ( 4.1A)
None
None
None
None
 1.26A 3r9cA-1bh6A:
undetectable		 3r9cA-1bh6A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 8 ILE A 107
LEU A 126
ILE A 122
GLY A  65
 1BH  A 300 ( 4.9A)
1BH  A 300 (-4.0A)
None
None
 0.79A 4hb8A-1bh6A:
undetectable		 4hb8A-1bh6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 PRO A 129
ALA A 153
ASN A 163
GLY A 193
LEU A 196
 None
 1.05A 4oaeA-1bh6A:
undetectable		 4oaeA-1bh6A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 GLY A 229
ALA A 228
VAL A 150
LEU A 250
ILE A  11
 None
 1.23A 4pd9A-1bh6A:
0.0		 4pd9A-1bh6A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 VAL A 148
LEU A 250
GLY A  23
ALA A 232
SER A 236
 None
 1.11A 4ph9A-1bh6A:
0.5		 4ph9A-1bh6A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 10 VAL A 148
LEU A 250
GLY A  23
ALA A 232
SER A 236
 None
 1.12A 4ph9B-1bh6A:
0.0		 4ph9B-1bh6A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 THR A  71
GLY A  83
HIS A  67
LEU A  82
SER A 216
 None
 1.22A 4pooA-1bh6A:
1.1		 4pooA-1bh6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 8 LEU A 233
VAL A  84
ILE A 268
ALA A 273
LEU A 250
 None
 1.27A 4qrcA-1bh6A:
undetectable		 4qrcA-1bh6A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 6 SER A 221
ALA A 152
HIS A  64
LEU A 126
 1BH  A 300 ( 1.7A)
1BH  A 300 ( 3.7A)
1BH  A 300 ( 3.0A)
1BH  A 300 (-4.0A)
 1.28A 5dzkB-1bh6A:
2.7
5dzkP-1bh6A:
undetectable		 5dzkB-1bh6A:
22.54
5dzkP-1bh6A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 HIS A  67
GLY A  65
HIS A 226
ALA A 228
SER A 190
 None
 1.05A 5igyA-1bh6A:
0.0		 5igyA-1bh6A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 6 ILE A  93
GLY A  63
ASN A  62
ILE A  30
 None
None
1BH  A 300 ( 4.6A)
None
 0.89A 5j4nB-1bh6A:
0.0		 5j4nB-1bh6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.01A 5kirA-1bh6A:
undetectable		 5kirA-1bh6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 1BH  A 300 ( 3.7A)
None
None
None
None
 1.05A 5kirB-1bh6A:
0.0		 5kirB-1bh6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 GLY A 154
SER A 190
ARG A 186
GLY A 157
 1BH  A 300 (-3.5A)
None
None
None
 1.13A 5kprA-1bh6A:
undetectable		 5kprA-1bh6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 8 VAL A 246
ILE A 234
ALA A 230
VAL A 150
VAL A 148
 None
 1.23A 5l94A-1bh6A:
0.0		 5l94A-1bh6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 8 VAL A 246
ILE A 234
ALA A 232
VAL A 150
VAL A 148
 None
 1.29A 5l94A-1bh6A:
0.0		 5l94A-1bh6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.29A 5v0iA-1bh6A:
undetectable		 5v0iA-1bh6A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.32A 5v0iB-1bh6A:
undetectable		 5v0iB-1bh6A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		5 / 11 GLY A 229
ALA A 230
ALA A  85
PRO A  86
VAL A  28
 None
 1.16A 5yk2A-1bh6A:
0.0		 5yk2A-1bh6A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
None
1BH  A 300 ( 4.8A)
None
 1.18A 5yodB-1bh6A:
0.0		 5yodB-1bh6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
None
1BH  A 300 ( 4.8A)
None
 1.21A 5yodD-1bh6A:
undetectable		 5yodD-1bh6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 1bh6 SUBTILISIN DY
(Bacillus
licheniformis) 		4 / 5 GLN A   2
THR A   3
HIS A  67
GLY A  83
 CA  A 501 (-3.5A)
None
None
None
 1.19A 6gbnC-1bh6A:
4.7		 6gbnC-1bh6A:
23.47