SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1bhd UTROPHIN
(Homo
sapiens) 		5 / 12 ALA A 184
ALA A 187
THR A 163
VAL A 160
LEU A 196
 None
 1.27A 1cbrA-1bhdA:
undetectable		 1cbrA-1bhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1bhd UTROPHIN
(Homo
sapiens) 		5 / 12 ALA A 184
ALA A 187
THR A 163
VAL A 160
LEU A 196
 None
 1.27A 1cbrB-1bhdA:
undetectable		 1cbrB-1bhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 1bhd UTROPHIN
(Homo
sapiens) 		4 / 7 PHE A 215
ASN A 186
ALA A 184
LEU A 247
 None
 0.97A 3t3sC-1bhdA:
undetectable		 3t3sC-1bhdA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1bhd UTROPHIN
(Homo
sapiens) 		5 / 8 PHE A 215
ASN A 186
ALA A 184
LEU A 247
LEU A 250
 None
 1.04A 4ejgB-1bhdA:
undetectable		 4ejgB-1bhdA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 1bhd UTROPHIN
(Homo
sapiens) 		5 / 7 PHE A 215
ASN A 186
ALA A 184
LEU A 247
LEU A 250
 None
 1.09A 4ejgC-1bhdA:
undetectable		 4ejgC-1bhdA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 1bhd UTROPHIN
(Homo
sapiens) 		4 / 6 LEU A 189
TRP A 199
LEU A 211
VAL A 160
 None
 1.01A 4udaA-1bhdA:
undetectable		 4udaA-1bhdA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bhd UTROPHIN
(Homo
sapiens) 		4 / 8 VAL A 253
LEU A 254
LEU A 196
ALA A 218
 None
 0.75A 5f1aA-1bhdA:
undetectable		 5f1aA-1bhdA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 1bhd UTROPHIN
(Homo
sapiens) 		5 / 12 TYR A 246
LEU A 247
GLY A 182
LEU A 189
HIS A 192
 None
 1.06A 5fsaA-1bhdA:
undetectable		 5fsaA-1bhdA:
15.20