SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.13A 1fkjA-1bheA:
undetectable		 1fkjA-1bheA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		3 / 3 TRP A 135
VAL A 132
TRP A 134
 None
 0.99A 1gmkC-1bheA:
undetectable
1gmkD-1bheA:
undetectable		 1gmkC-1bheA:
3.31
1gmkD-1bheA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.11A 1tcoC-1bheA:
undetectable		 1tcoC-1bheA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 THR A 237
GLY A 256
THR A 259
VAL A 291
VAL A 262
 None
 1.29A 2a1nA-1bheA:
undetectable		 2a1nA-1bheA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.13A 2fkeA-1bheA:
undetectable		 2fkeA-1bheA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 VAL A  63
ILE A 113
LEU A  73
ALA A 105
ASP A  68
 None
 1.37A 2iyfB-1bheA:
undetectable		 2iyfB-1bheA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		3 / 3 ARG A  74
THR A  49
VAL A  51
 None
 0.88A 2q64A-1bheA:
0.0		 2q64A-1bheA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ASN A 171
GLY A 203
HIS A 176
ILE A 214
ASP A 224
 None
 1.26A 3a25A-1bheA:
undetectable		 3a25A-1bheA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 GLY A 203
HIS A 176
ILE A 214
ASP A 224
ASN A 245
 None
 1.41A 3a25A-1bheA:
undetectable		 3a25A-1bheA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 8 PHE A  52
THR A  26
ILE A  29
THR A  28
 None
 0.93A 3bpxA-1bheA:
0.0
3bpxB-1bheA:
0.0		 3bpxA-1bheA:
17.30
3bpxB-1bheA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 8 VAL A 304
VAL A 299
ASN A 277
GLY A 278
 None
 0.80A 3hjoB-1bheA:
0.0		 3hjoB-1bheA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 4 ASP A 284
GLY A 319
LYS A 317
GLU A 318
 None
 1.47A 3hznD-1bheA:
0.0		 3hznD-1bheA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 7 VAL A 304
VAL A 299
ASN A 277
GLY A 278
 None
 0.84A 3kmoB-1bheA:
undetectable		 3kmoB-1bheA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O0Q_A_ADNA1004_1
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 9 ASN A 110
SER A  64
GLY A 112
THR A 186
THR A 163
 None
 1.23A 3o0qA-1bheA:
0.0		 3o0qA-1bheA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 LEU A  59
ALA A  41
GLY A  39
GLY A 112
SER A 111
 None
 1.21A 3ou7A-1bheA:
undetectable		 3ou7A-1bheA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 LEU A  59
ALA A  41
GLY A  39
GLY A 112
SER A 111
 None
 1.22A 3ou7D-1bheA:
undetectable		 3ou7D-1bheA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 10 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.13A 3uqaA-1bheA:
undetectable		 3uqaA-1bheA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.16A 4driA-1bheA:
undetectable		 4driA-1bheA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.17A 4drjA-1bheA:
undetectable		 4drjA-1bheA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 10 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.10A 4dz3A-1bheA:
undetectable		 4dz3A-1bheA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 10 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.14A 4laxA-1bheA:
undetectable		 4laxA-1bheA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 10 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.14A 4qt2A-1bheA:
undetectable		 4qt2A-1bheA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ALA A 220
ALA A 227
MET A 253
GLY A 252
PHE A 247
 None
 1.25A 4r29C-1bheA:
0.0		 4r29C-1bheA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.16A 5b8iC-1bheA:
undetectable		 5b8iC-1bheA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.12A 5gpgA-1bheA:
undetectable		 5gpgA-1bheA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ALA A 105
PHE A 162
GLY A 184
THR A 213
SER A 159
 None
 1.37A 5hfjA-1bheA:
undetectable		 5hfjA-1bheA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ALA A 105
PHE A 162
GLY A 184
THR A 213
SER A 159
 None
 1.34A 5hfjC-1bheA:
undetectable		 5hfjC-1bheA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.15A 5hkgA-1bheA:
undetectable		 5hkgA-1bheA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.20A 5hw8D-1bheA:
undetectable		 5hw8D-1bheA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 11 ASP A 224
VAL A 267
ILE A 242
ILE A 204
PHE A 247
 None
 1.20A 5hw8G-1bheA:
undetectable		 5hw8G-1bheA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 7 GLY A 184
PHE A 185
SER A 209
ASN A 110
 None
 1.10A 5n5dB-1bheA:
undetectable		 5n5dB-1bheA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		4 / 8 LEU A  65
ALA A  75
VAL A  42
GLN A  30
 None
 0.98A 5nu7A-1bheA:
undetectable		 5nu7A-1bheA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 8 ILE A 214
ILE A 204
ILE A 219
ASN A 225
MET A 253
 None
 1.49A 5numA-1bheA:
0.0		 5numA-1bheA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 LEU A 169
SER A  54
ILE A 103
PHE A  82
THR A  26
 None
 1.39A 6djzB-1bheA:
0.0		 6djzB-1bheA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 PHE A 162
ILE A 156
THR A 190
LEU A 169
PHE A 102
 None
 1.14A 6e8qA-1bheA:
0.0		 6e8qA-1bheA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 1bhe POLYGALACTURONASE
(Pectobacterium
carotovorum) 		5 / 12 GLY A 250
GLY A 274
ASP A 223
ILE A 204
VAL A 304
 None
 0.88A 6mhtA-1bheA:
undetectable		 6mhtA-1bheA:
20.67