SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		5 / 7 GLY A 583
ARG A 577
ILE A 629
TYR A 626
GLY A 347
 None
 1.48A 11gsB-1bhgA:
undetectable		 11gsB-1bhgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.87A 1a7yB-1bhgA:
undetectable		 1a7yB-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.88A 1dscC-1bhgA:
undetectable		 1dscC-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.72A 1dscC-1bhgA:
undetectable		 1dscC-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 7 ARG A 382
TRP A 587
TYR A 508
ARG A 600
 None
 1.48A 1f9gA-1bhgA:
0.5		 1f9gA-1bhgA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.85A 1fjaC-1bhgA:
undetectable		 1fjaC-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.85A 1fjaD-1bhgA:
undetectable		 1fjaD-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.83A 1i3wG-1bhgA:
undetectable		 1i3wG-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.85A 1i3wH-1bhgA:
undetectable		 1i3wH-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.83A 1mnvD-1bhgA:
undetectable		 1mnvD-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.85A 1ovfB-1bhgA:
undetectable		 1ovfB-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.85A 1unjL-1bhgA:
undetectable		 1unjL-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.85A 1unjR-1bhgA:
undetectable		 1unjR-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.84A 1unjW-1bhgA:
undetectable		 1unjW-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.86A 1unmE-1bhgA:
undetectable		 1unmE-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 117
PRO A 224
THR A 223
 None
 0.84A 1unmF-1bhgA:
undetectable		 1unmF-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 223
THR A 117
PRO A 224
 None
 0.86A 1unmF-1bhgA:
undetectable		 1unmF-1bhgA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 6 GLU A 352
TYR A 388
ASP A 369
PHE A 589
 None
 1.36A 2a3bB-1bhgA:
14.0		 2a3bB-1bhgA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 LEU A 565
TYR A 569
GLY A 572
 None
 0.45A 2ocuA-1bhgA:
undetectable		 2ocuA-1bhgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		5 / 9 GLY A 583
ARG A 577
ILE A 629
TYR A 626
GLY A 347
 None
 1.46A 3csjB-1bhgA:
undetectable		 3csjB-1bhgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 THR A 599
LYS A 359
GLU A 544
 None
 0.98A 3ijdB-1bhgA:
12.7		 3ijdB-1bhgA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 6 GLU A 624
TRP A 375
PRO A 615
ARG A 623
 None
 1.34A 3oxvA-1bhgA:
0.0		 3oxvA-1bhgA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 5 SER A 447
PRO A 387
TYR A 388
VAL A 433
 None
 1.15A 3sufC-1bhgA:
0.5		 3sufC-1bhgA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		5 / 11 LEU A 373
PHE A 343
ILE A 629
VAL A 348
LEU A 585
 None
 1.15A 3w67A-1bhgA:
1.0		 3w67A-1bhgA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 7 VAL A 233
VAL A 244
LEU A 280
VAL A 270
 None
 0.95A 4e1gB-1bhgA:
0.0		 4e1gB-1bhgA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 LEU A 322
MET A 393
TYR A 301
 None
 0.70A 4p6xG-1bhgA:
0.0		 4p6xG-1bhgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		5 / 12 ALA A 493
LEU A 501
ASN A 450
PHE A 481
SER A 447
 None
 1.15A 4pd5A-1bhgA:
0.8		 4pd5A-1bhgA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 ALA A 171
TRP A  98
VAL A  99
 None
NAG  A 651 (-3.9A)
None
 0.36A 4w9nC-1bhgA:
0.0		 4w9nC-1bhgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		5 / 12 LEU A 166
ILE A 168
ILE A 123
VAL A 119
LEU A 156
 None
 0.91A 4y0sA-1bhgA:
0.3		 4y0sA-1bhgA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 8 PHE A  59
GLY A  58
ARG A 167
TRP A 133
 None
 0.95A 5gqbA-1bhgA:
12.6		 5gqbA-1bhgA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 VAL A 105
ARG A 216
PRO A  80
 None
 0.61A 5koxA-1bhgA:
0.3		 5koxA-1bhgA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 8 LEU A 585
ILE A 404
PHE A 345
ARG A 382
 None
 1.05A 5m0oC-1bhgA:
0.0		 5m0oC-1bhgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 5 LEU A 107
VAL A 105
GLU A  40
LEU A 220
 None
 1.12A 5xooB-1bhgA:
0.0		 5xooB-1bhgA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 8 GLU A 544
PHE A 206
HIS A 127
LEU A 176
 None
 1.11A 5y2tB-1bhgA:
0.0		 5y2tB-1bhgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 4 GLY A 145
LEU A 147
VAL A 429
GLU A 432
 None
 1.39A 5yw0A-1bhgA:
0.6		 5yw0A-1bhgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 9 VAL A 120
LEU A  28
VAL A 250
SER A 249
 None
 0.97A 6c2mD-1bhgA:
0.0		 6c2mD-1bhgA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 8 LEU A 621
LEU A 622
LEU A 571
GLY A 572
 None
 0.67A 6ce2A-1bhgA:
0.0		 6ce2A-1bhgA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 LEU A 565
ASN A 349
LEU A 622
 None
 0.60A 6exiA-1bhgA:
0.7		 6exiA-1bhgA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 LEU A 573
ASN A 349
LEU A 622
 None
 0.65A 6exiA-1bhgA:
0.7		 6exiA-1bhgA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		3 / 3 TRP A 446
ILE A 404
ASP A 405
 None
 0.49A 6i0y7-1bhgA:
undetectable		 6i0y7-1bhgA:
4.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 4 HIS A 570
LEU A 514
TYR A 561
GLY A 542
 None
 1.40A 6n91A-1bhgA:
3.4		 6n91A-1bhgA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1bhg BETA-GLUCURONIDASE
(Homo
sapiens) 		4 / 4 HIS A 570
LEU A 514
TYR A 561
GLY A 542
 None
 1.40A 6n91B-1bhgA:
6.6		 6n91B-1bhgA:
9.73