SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 1bhq CD11B
(Homo
sapiens) 		4 / 7 PHE 1 275
THR 1 211
ILE 1 316
GLY 1 270
 None
 0.82A 2v0mB-1bhq1:
undetectable		 2v0mB-1bhq1:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1bhq CD11B
(Homo
sapiens) 		5 / 12 ASN 1 310
THR 1 159
VAL 1 160
GLN 1 163
LEU 1 164
 None
 1.37A 2xrlA-1bhq1:
undetectable		 2xrlA-1bhq1:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1bhq CD11B
(Homo
sapiens) 		4 / 7 VAL 1 160
ILE 1 269
ILE 1 308
GLN 1 309
 None
 1.04A 3hgxA-1bhq1:
undetectable		 3hgxA-1bhq1:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1bhq CD11B
(Homo
sapiens) 		4 / 6 LYS 1 187
ASP 1 134
PRO 1 193
LEU 1 198
 None
 1.30A 5bmvB-1bhq1:
undetectable		 5bmvB-1bhq1:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 1bhq CD11B
(Homo
sapiens) 		4 / 8 GLN 1 298
GLY 1 270
GLU 1 283
ASP 1 140
 None
None
None
CD  1 901 ( 3.9A)
 1.06A 5vlmD-1bhq1:
undetectable		 5vlmD-1bhq1:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1bhq CD11B
(Homo
sapiens) 		4 / 7 PHE 1 137
ILE 1 240
PHE 1 275
ILE 1 236
 None
 0.86A 6b5vA-1bhq1:
undetectable
6b5vB-1bhq1:
undetectable		 6b5vA-1bhq1:
13.99
6b5vB-1bhq1:
13.99