SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1bht HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens) 		3 / 3 GLN A 150
HIS A 158
PRO A 194
 None
 0.92A 1d8cA-1bhtA:
undetectable		 1d8cA-1bhtA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1bht HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens) 		4 / 6 PHE A 190
GLU A 199
GLN A 150
LYS A 148
 EPE  A   1 (-4.4A)
None
None
None
 1.39A 1l2iB-1bhtA:
undetectable		 1l2iB-1bhtA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1bht HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens) 		3 / 3 ASP A 117
PHE A  89
LEU A  97
 None
 0.74A 2zi9A-1bhtA:
undetectable		 2zi9A-1bhtA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1bht HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens) 		3 / 3 GLY A 146
THR A 143
GLU A 199
 None
 0.65A 6b58A-1bhtA:
undetectable		 6b58A-1bhtA:
14.11