SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 134
LEU A 162
ILE A 116
MET A 123
 None
 0.99A 1n13I-1bhwA:
0.0
1n13L-1bhwA:
0.0		 1n13I-1bhwA:
9.04
1n13L-1bhwA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		3 / 3 ASP A  57
THR A  90
GLU A 181
 None
 0.85A 1pj7A-1bhwA:
undetectable		 1pj7A-1bhwA:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		9 / 10 TRP A  16
HIS A  54
PHE A  94
TRP A 137
GLU A 181
GLU A 217
ASP A 245
ASP A 292
LYS A 294
 None
 0.32A 1xidA-1bhwA:
57.7		 1xidA-1bhwA:
66.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
THR A  90
TRP A 137
ASP A 255
ASP A 245
 None
 1.44A 1xihA-1bhwA:
57.7		 1xihA-1bhwA:
66.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
ASP A 245
 None
 1.46A 1xihA-1bhwA:
57.7		 1xihA-1bhwA:
66.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		9 / 12 TRP A  16
HIS A  54
THR A  90
PHE A  94
VAL A 135
TRP A 137
LYS A 183
ASP A 255
ASP A 292
 None
 0.63A 1xihA-1bhwA:
57.7		 1xihA-1bhwA:
66.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		10 / 12 TRP A  16
HIS A  54
THR A  90
PHE A  94
VAL A 135
TRP A 137
LYS A 183
GLU A 217
ASP A 245
ASP A 292
 None
 0.23A 1xihA-1bhwA:
57.7		 1xihA-1bhwA:
66.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 PHE A  99
ILE A 116
ALA A 115
THR A  91
VAL A 119
 None
 1.16A 2g78A-1bhwA:
undetectable		 2g78A-1bhwA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 ILE A 116
MET A 123
LEU A 134
LEU A 162
 None
 1.01A 2qqcB-1bhwA:
0.0
2qqcC-1bhwA:
0.0		 2qqcB-1bhwA:
13.60
2qqcC-1bhwA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 134
LEU A 162
ILE A 116
MET A 123
 None
 0.97A 2qqcA-1bhwA:
0.0
2qqcF-1bhwA:
0.0		 2qqcA-1bhwA:
10.34
2qqcF-1bhwA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 134
LEU A 162
ILE A 116
MET A 123
 None
 0.99A 2qqcG-1bhwA:
0.0
2qqcJ-1bhwA:
0.0		 2qqcG-1bhwA:
10.34
2qqcJ-1bhwA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 134
LEU A 162
ILE A 116
MET A 123
 None
 0.98A 2qqcI-1bhwA:
0.0
2qqcL-1bhwA:
0.0		 2qqcI-1bhwA:
10.34
2qqcL-1bhwA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 134
LEU A 162
ILE A 116
MET A 123
 None
 0.96A 2qqdA-1bhwA:
0.0
2qqdE-1bhwA:
0.0		 2qqdA-1bhwA:
10.34
2qqdE-1bhwA:
14.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 257
 None
 1.37A 2xinA-1bhwA:
62.6		 2xinA-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 None
 1.33A 2xinA-1bhwA:
62.6		 2xinA-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.30A 2xinA-1bhwA:
62.6		 2xinA-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.26A 2xinA-1bhwA:
62.6		 2xinA-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 255
ASP A 245
 None
 1.34A 2xinB-1bhwA:
62.1		 2xinB-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
ASP A 257
 None
 1.46A 2xinB-1bhwA:
62.1		 2xinB-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.40A 2xinB-1bhwA:
62.1		 2xinB-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
ASP A 257
 None
 1.47A 2xinC-1bhwA:
62.2		 2xinC-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.35A 2xinC-1bhwA:
62.2		 2xinC-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 245
 None
 1.38A 2xinD-1bhwA:
62.3		 2xinD-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 257
 None
 1.36A 2xinD-1bhwA:
62.3		 2xinD-1bhwA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.39A 2xinD-1bhwA:
62.3		 2xinD-1bhwA:
99.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
ASN A 215
GLY A  14
HIS A 290
MET A  88
 None
 1.39A 3g1uA-1bhwA:
undetectable		 3g1uA-1bhwA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		3 / 3 GLU A 217
GLU A 181
TRP A  16
 None
 1.25A 3hrdA-1bhwA:
0.0
3hrdE-1bhwA:
0.2
3hrdF-1bhwA:
0.0		 3hrdA-1bhwA:
25.87
3hrdE-1bhwA:
25.87
3hrdF-1bhwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 ASN A 267
PHE A  11
ILE A 232
THR A 229
LEU A 275
 None
 1.29A 3iv6A-1bhwA:
undetectable		 3iv6A-1bhwA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 LEU A 176
VAL A  59
ALA A 131
LEU A  79
ILE A  51
 None
 1.02A 3ku1H-1bhwA:
undetectable		 3ku1H-1bhwA:
21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 217
ASP A 245
ASP A 257
 None
 1.21A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
ASP A 292
 None
 1.43A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.23A 3ximA-1bhwA:
62.9		 3ximA-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 245
 None
 1.40A 3ximB-1bhwA:
62.4		 3ximB-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 None
 1.22A 3ximB-1bhwA:
62.4		 3ximB-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.24A 3ximB-1bhwA:
62.4		 3ximB-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.34A 3ximC-1bhwA:
62.0		 3ximC-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 None
 1.39A 3ximC-1bhwA:
62.0		 3ximC-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 None
 1.15A 3ximC-1bhwA:
62.0		 3ximC-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.23A 3ximC-1bhwA:
62.0		 3ximC-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 245
 None
 1.34A 3ximD-1bhwA:
62.3		 3ximD-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 None
 1.19A 3ximD-1bhwA:
62.3		 3ximD-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.24A 3ximD-1bhwA:
62.3		 3ximD-1bhwA:
98.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		8 / 12 HIS A  54
MET A  88
THR A  90
VAL A 135
ASN A 215
GLU A 217
ASP A 245
ASP A 257
 None
 1.28A 4dvoA-1bhwA:
57.6		 4dvoA-1bhwA:
66.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
ASN A 215
GLU A 217
ASP A 245
ASP A 255
 None
 0.27A 4dvoA-1bhwA:
57.6		 4dvoA-1bhwA:
66.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		3 / 3 GLU A 186
ASP A 255
ASP A  24
 None
 0.79A 4gc9A-1bhwA:
undetectable		 4gc9A-1bhwA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 7 LEU A 120
LYS A 118
GLN A 122
LEU A 134
 None
 1.10A 4ib4A-1bhwA:
undetectable		 4ib4A-1bhwA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		3 / 3 ASN A  92
ASP A  57
ASP A 292
 None
 0.88A 4obwD-1bhwA:
undetectable		 4obwD-1bhwA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 ARG A 326
ALA A 386
ASP A 273
SER A 338
 None
 1.12A 4ot2A-1bhwA:
undetectable		 4ot2A-1bhwA:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
THR A  90
TRP A 137
ASP A 255
ASP A 245
 None
 1.42A 4xiaA-1bhwA:
57.6		 4xiaA-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
ASP A 245
 None
 1.44A 4xiaA-1bhwA:
57.6		 4xiaA-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
ASP A 292
 None
 1.48A 4xiaA-1bhwA:
57.6		 4xiaA-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		10 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
ASP A 245
ASP A 255
ASP A 292
 None
 0.57A 4xiaA-1bhwA:
57.6		 4xiaA-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		10 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
ASP A 245
ASP A 292
 None
 0.19A 4xiaA-1bhwA:
57.6		 4xiaA-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.28A 4xiaB-1bhwA:
57.6		 4xiaB-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 245
 None
 1.37A 4xiaB-1bhwA:
57.6		 4xiaB-1bhwA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 292
 None
 0.17A 4xiaB-1bhwA:
57.6		 4xiaB-1bhwA:
67.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 10 PHE A 260
VAL A 272
GLU A 276
LEU A 318
PHE A  11
 None
 1.34A 4zmeB-1bhwA:
undetectable		 4zmeB-1bhwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 LEU A 226
GLN A 222
GLY A 251
ASP A 257
ASN A 220
 None
 1.44A 5d0yA-1bhwA:
0.0		 5d0yA-1bhwA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 HIS A 243
ASP A 245
HIS A 290
MET A  88
 None
 1.44A 5m45A-1bhwA:
0.1		 5m45A-1bhwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 HIS A 243
ASP A 245
HIS A 290
MET A  88
 None
 1.43A 5m45D-1bhwA:
0.1		 5m45D-1bhwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 HIS A 243
ASP A 245
HIS A 290
MET A  88
 None
 1.43A 5m45G-1bhwA:
0.0		 5m45G-1bhwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 HIS A 243
ASP A 245
HIS A 290
MET A  88
 None
 1.43A 5m45J-1bhwA:
0.0		 5m45J-1bhwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 LEU A 134
GLY A 126
LEU A 165
LEU A 164
LEU A 120
 None
 1.04A 5nfjB-1bhwA:
undetectable		 5nfjB-1bhwA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.38A 5nhaA-1bhwA:
39.2		 5nhaA-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 245
ASP A 292
 None
 0.22A 5nhaA-1bhwA:
39.2		 5nhaA-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 245
ASP A 292
 None
 0.22A 5nhaB-1bhwA:
39.2		 5nhaB-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 245
ASP A 292
 None
 0.22A 5nhaC-1bhwA:
39.1		 5nhaC-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.38A 5nhaD-1bhwA:
39.2		 5nhaD-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
ASP A 245
ASP A 292
 None
 0.22A 5nhaD-1bhwA:
39.2		 5nhaD-1bhwA:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 6 HIS A 243
HIS A 290
THR A  52
TRP A  16
 None
 1.31A 5ogjA-1bhwA:
undetectable		 5ogjA-1bhwA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 VAL A  89
PHE A  53
LEU A  79
GLY A 130
ALA A 131
 None
 1.46A 5x23A-1bhwA:
0.0		 5x23A-1bhwA:
22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 None
 1.21A 5ximA-1bhwA:
63.2		 5ximA-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 None
 1.36A 5ximA-1bhwA:
63.2		 5ximA-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.15A 5ximA-1bhwA:
63.2		 5ximA-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
ASP A 245
 None
 1.44A 5ximB-1bhwA:
62.5		 5ximB-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 217
ASP A 245
ASP A 257
 None
 1.29A 5ximB-1bhwA:
62.5		 5ximB-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
ASP A 292
 None
 1.41A 5ximB-1bhwA:
62.5		 5ximB-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.18A 5ximB-1bhwA:
62.5		 5ximB-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		7 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
 None
 1.26A 5ximC-1bhwA:
62.5		 5ximC-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 257
 None
 1.29A 5ximC-1bhwA:
62.5		 5ximC-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.15A 5ximC-1bhwA:
62.5		 5ximC-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 181
GLU A 217
ASP A 292
 None
 1.34A 5ximD-1bhwA:
62.6		 5ximD-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 None
 1.36A 5ximD-1bhwA:
62.6		 5ximD-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		6 / 12 THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 None
 1.13A 5ximD-1bhwA:
62.6		 5ximD-1bhwA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		11 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
ASP A 245
ASP A 255
ASP A 292
 None
 0.14A 5ximD-1bhwA:
62.6		 5ximD-1bhwA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		5 / 12 GLY A 263
GLY A 261
ASN A 267
ALA A 268
PRO A 252
 None
 1.11A 6b3aA-1bhwA:
2.9		 6b3aA-1bhwA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 8 TRP A  20
ASP A  57
ASP A 292
GLU A 181
 None
 1.27A 6mn4B-1bhwA:
0.0		 6mn4B-1bhwA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1bhw XYLOSE ISOMERASE
(Actinoplanes
missouriensis) 		4 / 8 TRP A  20
ASP A  57
ASP A 292
GLU A 181
 None
 1.06A 6mn4C-1bhwA:
0.0		 6mn4C-1bhwA:
21.70