SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 133
GLY A 439
ILE A 270
GLY A 130
ALA A 137
 FAD  A 600 (-3.4A)
FAD  A 600 (-3.3A)
None
None
None
 1.13A 1jg2A-1bhyA:
3.3		 1jg2A-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 134
GLY A 129
ILE A 270
LEU A 128
GLY A 455
 None
FAD  A 600 (-3.0A)
None
None
None
 0.85A 1jg2A-1bhyA:
3.3		 1jg2A-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 129
GLU A 152
ARG A 153
ASP A 232
GLY A 233
 FAD  A 600 (-3.0A)
FAD  A 600 (-2.5A)
FAD  A 600 (-3.6A)
FAD  A 600 (-3.9A)
FAD  A 600 (-3.8A)
 1.09A 1jg3A-1bhyA:
3.0		 1jg3A-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 134
GLY A 129
ILE A 270
LEU A 128
GLY A 455
 None
FAD  A 600 (-3.0A)
None
None
None
 0.85A 1jg3A-1bhyA:
3.0		 1jg3A-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 129
GLU A 152
ARG A 153
ASP A 232
GLY A 233
 FAD  A 600 (-3.0A)
FAD  A 600 (-2.5A)
FAD  A 600 (-3.6A)
FAD  A 600 (-3.9A)
FAD  A 600 (-3.8A)
 1.07A 1jg3B-1bhyA:
undetectable		 1jg3B-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 134
GLY A 129
ILE A 270
LEU A 128
GLY A 455
 None
FAD  A 600 (-3.0A)
None
None
None
 0.83A 1jg3B-1bhyA:
undetectable		 1jg3B-1bhyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 PHE A 528
LEU A 587
ALA A 586
GLY A 566
ILE A 565
 None
 1.01A 1kglA-1bhyA:
0.0		 1kglA-1bhyA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 THR A 156
GLY A 130
GLY A 131
VAL A 228
GLY A 215
 None
None
FAD  A 600 (-3.5A)
None
None
 0.89A 1n2xB-1bhyA:
undetectable		 1n2xB-1bhyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 439
ALA A 451
ALA A 437
ASP A 440
ILE A 441
 FAD  A 600 (-3.3A)
FAD  A 600 ( 3.8A)
None
FAD  A 600 (-2.7A)
None
 1.08A 1nt2A-1bhyA:
3.0		 1nt2A-1bhyA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 134
GLY A 129
ILE A 270
TYR A 436
HIS A 434
 None
FAD  A 600 (-3.0A)
None
None
None
 1.15A 1p91A-1bhyA:
undetectable		 1p91A-1bhyA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 8 ILE A 540
GLY A 539
GLY A 538
ILE A 527
ALA A 583
 None
 1.27A 1sguA-1bhyA:
undetectable		 1sguA-1bhyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 8 ALA A 555
ILE A 565
ILE A 579
GLY A 538
ILE A 527
 None
 1.28A 1sh9A-1bhyA:
0.0		 1sh9A-1bhyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 8 ALA A 582
ILE A 565
ILE A 535
GLY A 538
ILE A 549
 None
 1.38A 1sh9A-1bhyA:
0.0		 1sh9A-1bhyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 VAL A 126
GLY A 233
LEU A 128
TYR A 123
ILE A 229
 None
FAD  A 600 (-3.8A)
None
None
None
 1.27A 1sq5D-1bhyA:
0.2		 1sq5D-1bhyA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.29A 1x70A-1bhyA:
undetectable		 1x70A-1bhyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.30A 1x70B-1bhyA:
undetectable		 1x70B-1bhyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 TYR A 391
VAL A 377
THR A 365
GLY A 381
ALA A 384
 None
 1.44A 2coiA-1bhyA:
undetectable
2coiB-1bhyA:
undetectable		 2coiA-1bhyA:
21.65
2coiB-1bhyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 VAL A 377
THR A 378
PHE A 379
ASP A 328
 None
 1.03A 2kotB-1bhyA:
undetectable		 2kotB-1bhyA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 129
GLY A 134
LEU A 157
ILE A 270
LEU A 241
 FAD  A 600 (-3.0A)
None
None
None
None
 0.86A 2nxeA-1bhyA:
undetectable		 2nxeA-1bhyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 129
GLY A 134
LEU A 157
ILE A 270
LEU A 241
 FAD  A 600 (-3.0A)
None
None
None
None
 0.86A 2nxeB-1bhyA:
undetectable		 2nxeB-1bhyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.32A 2rguA-1bhyA:
undetectable		 2rguA-1bhyA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.26A 2rguB-1bhyA:
undetectable		 2rguB-1bhyA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1bhy P64K
(Neisseria
meningitidis) 		6 / 12 ALA A 555
ILE A 579
GLY A 538
ILE A 527
ALA A 583
ILE A 565
 None
 0.98A 2rkfB-1bhyA:
undetectable		 2rkfB-1bhyA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_T_CHDT1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.49A 2y69A-1bhyA:
0.0
2y69B-1bhyA:
0.0
2y69T-1bhyA:
0.0		 2y69A-1bhyA:
20.07
2y69B-1bhyA:
18.46
2y69T-1bhyA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 129
GLY A 134
LEU A 157
ILE A 270
LEU A 241
 FAD  A 600 (-3.0A)
None
None
None
None
 0.86A 2zbpA-1bhyA:
3.4		 2zbpA-1bhyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 ALA A 393
GLY A 317
THR A 318
LEU A 305
VAL A 329
 None
 1.16A 2zifB-1bhyA:
undetectable		 2zifB-1bhyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.50A 2zxwA-1bhyA:
0.0
2zxwB-1bhyA:
0.0
2zxwT-1bhyA:
0.0		 2zxwA-1bhyA:
20.07
2zxwB-1bhyA:
18.46
2zxwT-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.47A 3ag4A-1bhyA:
0.0
3ag4B-1bhyA:
0.0
3ag4T-1bhyA:
0.0		 3ag4A-1bhyA:
20.07
3ag4B-1bhyA:
18.46
3ag4T-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.31A 3bjmA-1bhyA:
undetectable		 3bjmA-1bhyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.30A 3bjmB-1bhyA:
undetectable		 3bjmB-1bhyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 129
GLY A 134
LEU A 157
ILE A 270
LEU A 241
 FAD  A 600 (-3.0A)
None
None
None
None
 0.89A 3cjtO-1bhyA:
undetectable		 3cjtO-1bhyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 ALA A 583
ALA A 586
HIS A 572
GLU A 577
 None
 0.83A 3dtuC-1bhyA:
undetectable
3dtuD-1bhyA:
0.0		 3dtuC-1bhyA:
21.70
3dtuD-1bhyA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 9 ALA A 555
GLY A 538
ILE A 527
ALA A 583
ILE A 565
 None
 0.85A 3ektB-1bhyA:
undetectable		 3ektB-1bhyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 273
ALA A 272
VAL A 127
ALA A 409
ILE A 407
 FAD  A 600 (-3.3A)
FAD  A 600 (-3.8A)
None
None
FAD  A 600 (-4.9A)
 0.80A 3ekwB-1bhyA:
undetectable		 3ekwB-1bhyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.29A 3g0bA-1bhyA:
undetectable		 3g0bA-1bhyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.26A 3g0bB-1bhyA:
undetectable		 3g0bB-1bhyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.29A 3g0bC-1bhyA:
undetectable		 3g0bC-1bhyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.27A 3g0bD-1bhyA:
undetectable		 3g0bD-1bhyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 SER A 169
LEU A 304
ILE A 306
SER A 291
GLY A 313
 FAD  A 600 ( 3.9A)
None
None
FAD  A 600 ( 4.2A)
None
 1.39A 3ijxB-1bhyA:
undetectable
3ijxD-1bhyA:
0.0		 3ijxB-1bhyA:
21.78
3ijxD-1bhyA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 ILE A 549
GLY A 546
GLY A 545
ALA A 478
VAL A 477
 None
 0.94A 3jb2A-1bhyA:
0.0		 3jb2A-1bhyA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 VAL A 228
SER A 136
PHE A 139
GLY A 219
ALA A 218
 None
 1.10A 3kk6A-1bhyA:
0.0		 3kk6A-1bhyA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 6 VAL A 487
VAL A 452
ILE A 474
MET A 558
 None
 0.79A 3mssD-1bhyA:
undetectable		 3mssD-1bhyA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		6 / 12 LEU A 157
ALA A 138
ILE A 269
GLY A 455
VAL A 452
ILE A 150
 None
 1.37A 3nu5A-1bhyA:
undetectable		 3nu5A-1bhyA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1bhy P64K
(Neisseria
meningitidis) 		3 / 3 GLY A 550
ILE A 474
VAL A 473
 None
 0.46A 3nv6A-1bhyA:
0.0		 3nv6A-1bhyA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		6 / 10 LEU A 157
ALA A 138
ILE A 269
GLY A 455
VAL A 452
ILE A 150
 None
 1.40A 3oxwB-1bhyA:
undetectable		 3oxwB-1bhyA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 ALA A 555
ILE A 579
GLY A 538
ILE A 527
ILE A 565
 None
 0.79A 3s45B-1bhyA:
undetectable		 3s45B-1bhyA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.27A 3w2tA-1bhyA:
undetectable		 3w2tA-1bhyA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.29A 3w2tB-1bhyA:
undetectable		 3w2tB-1bhyA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.48A 3x2qA-1bhyA:
0.0
3x2qB-1bhyA:
0.0
3x2qT-1bhyA:
0.0		 3x2qA-1bhyA:
20.07
3x2qB-1bhyA:
18.46
3x2qT-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 ILE A 435
GLY A 455
VAL A 424
ILE A 422
VAL A 442
 None
 1.02A 4c9lB-1bhyA:
0.0		 4c9lB-1bhyA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 GLY A 439
GLY A 273
ILE A 270
ASP A 440
PRO A 132
 FAD  A 600 (-3.3A)
FAD  A 600 (-3.3A)
None
FAD  A 600 (-2.7A)
FAD  A 600 (-3.4A)
 1.15A 4dcmA-1bhyA:
3.7		 4dcmA-1bhyA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
GLY A 134
TYR A 251
TYR A 154
VAL A 164
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
None
 1.45A 4ffwB-1bhyA:
undetectable		 4ffwB-1bhyA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
GLY A 233
VAL A 164
TYR A 251
VAL A 160
 FAD  A 600 (-2.5A)
FAD  A 600 (-3.8A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.4A)
 1.49A 4ffwB-1bhyA:
undetectable		 4ffwB-1bhyA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.28A 4ffwB-1bhyA:
undetectable		 4ffwB-1bhyA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLY A 404
GLY A 420
ALA A 401
ALA A 272
ARG A 153
 None
None
None
FAD  A 600 (-3.8A)
FAD  A 600 (-3.6A)
 1.04A 4kicB-1bhyA:
3.7		 4kicB-1bhyA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 HIS A 184
GLU A 181
ASP A 180
SER A 481
 None
 1.10A 4uhxA-1bhyA:
1.2		 4uhxA-1bhyA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 HIS A 184
GLU A 181
ASP A 180
SER A 481
 None
 1.10A 4uhxA-1bhyA:
1.2		 4uhxA-1bhyA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1bhy P64K
(Neisseria
meningitidis) 		3 / 4 ARG A 153
GLY A 231
GLU A 152
 FAD  A 600 (-3.6A)
None
FAD  A 600 (-2.5A)
 0.65A 4z2dB-1bhyA:
0.0
4z2dC-1bhyA:
undetectable		 4z2dB-1bhyA:
23.61
4z2dC-1bhyA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 8 ALA A 271
VAL A 127
GLY A 133
ALA A 451
GLY A 455
 FAD  A 600 (-4.7A)
None
FAD  A 600 (-3.4A)
FAD  A 600 ( 3.8A)
None
 1.26A 4zjzB-1bhyA:
2.3		 4zjzB-1bhyA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 ALA A 555
ILE A 579
GLY A 538
ILE A 527
ILE A 565
 None
 0.77A 5e5kA-1bhyA:
undetectable		 5e5kA-1bhyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 7 GLY A 129
GLY A 131
GLU A 152
ASP A 232
 FAD  A 600 (-3.0A)
FAD  A 600 (-3.5A)
FAD  A 600 (-2.5A)
FAD  A 600 (-3.9A)
 0.81A 5ergB-1bhyA:
2.9		 5ergB-1bhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.49A 5iy5A-1bhyA:
0.0
5iy5B-1bhyA:
0.0
5iy5T-1bhyA:
0.0		 5iy5A-1bhyA:
20.07
5iy5B-1bhyA:
18.46
5iy5T-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 7 GLY A 537
GLY A 539
PHE A 523
LYS A 503
 None
 0.69A 5izfA-1bhyA:
undetectable		 5izfA-1bhyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 6 THR A 574
GLY A 576
GLU A 577
ILE A 565
 None
 0.81A 5kmfA-1bhyA:
0.6
5kmfC-1bhyA:
0.2		 5kmfA-1bhyA:
19.65
5kmfC-1bhyA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 GLU A 252
VAL A 160
GLY A 293
LEU A 295
 None
FAD  A 600 (-3.4A)
None
None
 0.85A 5sxqA-1bhyA:
0.0		 5sxqA-1bhyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 GLU A 252
VAL A 160
GLY A 293
LEU A 295
 None
FAD  A 600 (-3.4A)
None
None
 0.85A 5sxtA-1bhyA:
0.5		 5sxtA-1bhyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 GLU A 252
VAL A 160
GLY A 293
LEU A 295
 None
FAD  A 600 (-3.4A)
None
None
 0.84A 5sxtB-1bhyA:
0.5		 5sxtB-1bhyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1bhy P64K
(Neisseria
meningitidis) 		4 / 8 GLU A 252
VAL A 160
GLY A 293
LEU A 295
 None
FAD  A 600 (-3.4A)
None
None
 0.85A 5syjB-1bhyA:
0.3		 5syjB-1bhyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_T_CHDT101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.49A 5z85A-1bhyA:
0.0
5z85B-1bhyA:
0.0
5z85T-1bhyA:
0.0		 5z85A-1bhyA:
20.07
5z85B-1bhyA:
18.46
5z85T-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 12 GLU A 152
VAL A 164
TYR A 251
TYR A 154
VAL A 160
 FAD  A 600 (-2.5A)
None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.7A)
FAD  A 600 (-3.4A)
 1.28A 6b1eB-1bhyA:
undetectable		 6b1eB-1bhyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 ALA A 401
VAL A 416
ALA A 409
ALA A 272
LEU A 406
 None
None
None
FAD  A 600 (-3.8A)
None
 1.29A 6h1lA-1bhyA:
0.0		 6h1lA-1bhyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 11 ALA A 401
VAL A 416
ALA A 409
ALA A 272
LEU A 406
 None
None
None
FAD  A 600 (-3.8A)
None
 1.23A 6h1lB-1bhyA:
0.0		 6h1lB-1bhyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 8 GLY A 542
PHE A 523
GLY A 576
SER A 578
ALA A 582
 None
 1.33A 6hu9H-1bhyA:
0.0
6hu9e-1bhyA:
undetectable		 6hu9H-1bhyA:
15.17
6hu9e-1bhyA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 9 MET A 548
GLY A 546
GLU A 483
THR A 480
GLY A 539
 None
 1.50A 6nmpA-1bhyA:
0.0
6nmpB-1bhyA:
0.0
6nmpT-1bhyA:
0.0		 6nmpA-1bhyA:
20.07
6nmpB-1bhyA:
18.46
6nmpT-1bhyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1bhy P64K
(Neisseria
meningitidis) 		5 / 10 GLY A 539
MET A 548
GLY A 546
GLU A 483
THR A 480
 None
 1.48A 6nmpG-1bhyA:
0.0
6nmpN-1bhyA:
0.0
6nmpO-1bhyA:
0.0		 6nmpG-1bhyA:
9.54
6nmpN-1bhyA:
20.07
6nmpO-1bhyA:
18.46