SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1bi7 MULTIPLE TUMOR
SUPPRESSOR
(Homo
sapiens) 		4 / 8 LEU B  16
VAL B  59
LEU B  62
ALA B  68
 None
 0.93A 1fiqC-1bi7B:
undetectable		 1fiqC-1bi7B:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1bi7 MULTIPLE TUMOR
SUPPRESSOR
(Homo
sapiens) 		4 / 7 ARG B 128
GLU B 119
ALA B 133
ALA B 134
 None
 1.03A 2ejfA-1bi7B:
undetectable		 2ejfA-1bi7B:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1bi7 MULTIPLE TUMOR
SUPPRESSOR
(Homo
sapiens) 		3 / 3 LEU B  97
LEU B  94
ARG B  87
 None
 0.75A 3hcnB-1bi7B:
undetectable		 3hcnB-1bi7B:
17.63