SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 1bih HEMOLIN
(Hyalophora
cecropia) 		5 / 12 LEU A 350
PRO A 315
THR A 390
VAL A 392
TYR A 311
 None
 1.01A 1cbsA-1bihA:
undetectable		 1cbsA-1bihA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 1bih HEMOLIN
(Hyalophora
cecropia) 		5 / 12 LEU A 350
PRO A 315
THR A 390
VAL A 392
TYR A 311
 None
 1.05A 2fr3A-1bihA:
undetectable		 2fr3A-1bihA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 8 LEU A 350
ARG A 354
SER A  89
VAL A 392
 None
 1.05A 2qd2A-1bihA:
undetectable		 2qd2A-1bihA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1bih HEMOLIN
(Hyalophora
cecropia) 		3 / 3 TYR A 243
ARG A 153
SER A 268
 None
PO4  A 396 (-3.3A)
PO4  A 396 (-4.7A)
 1.11A 4khpI-1bihA:
0.0
4khpJ-1bihA:
0.0		 4khpI-1bihA:
15.87
4khpJ-1bihA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		3 / 3 GLY A 373
GLU A 389
THR A 390
 None
 0.55A 4kouA-1bihA:
0.0		 4kouA-1bihA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 8 THR A  24
LEU A  64
TRP A  50
PHE A  66
 None
 1.16A 4m5mA-1bihA:
undetectable		 4m5mA-1bihA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bih HEMOLIN
(Hyalophora
cecropia) 		3 / 3 TYR A 246
ARG A 263
THR A 262
 None
 0.93A 5z84J-1bihA:
0.0		 5z84J-1bihA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		3 / 3 ARG A  91
ARG A 378
ASP A 385
 None
 0.96A 6d8pA-1bihA:
0.0		 6d8pA-1bihA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 5 LEU A 163
THR A 166
ARG A 271
ARG A 266
 None
 1.29A 6ew0B-1bihA:
0.0		 6ew0B-1bihA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 5 LEU A 163
THR A 166
ARG A 271
ARG A 266
 None
 1.29A 6ew0D-1bihA:
0.0		 6ew0D-1bihA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 5 LEU A 163
THR A 166
ARG A 271
ARG A 266
 None
 1.29A 6ew0H-1bihA:
0.0		 6ew0H-1bihA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 1bih HEMOLIN
(Hyalophora
cecropia) 		4 / 5 LEU A 163
THR A 166
ARG A 271
ARG A 266
 None
 1.29A 6ew0I-1bihA:
undetectable		 6ew0I-1bihA:
12.26