SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bik'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1bik BIKUNIN
(Homo
sapiens) 		4 / 7 LEU A  73
VAL A 103
ILE A  86
MET A  49
 None
 1.31A 3ik3A-1bikA:
undetectable		 3ik3A-1bikA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1bik BIKUNIN
(Homo
sapiens) 		4 / 6 ASN A  45
GLU A  69
TYR A  42
GLU A  52
 NAG  A 148 (-1.7A)
None
None
NAG  A 148 ( 4.0A)
 1.31A 4mi4A-1bikA:
undetectable		 4mi4A-1bikA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1bik BIKUNIN
(Homo
sapiens) 		4 / 7 ASN A  45
GLU A  69
TYR A  42
GLU A  52
 NAG  A 148 (-1.7A)
None
None
NAG  A 148 ( 4.0A)
 1.30A 4mj8C-1bikA:
undetectable		 4mj8C-1bikA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1bik BIKUNIN
(Homo
sapiens) 		4 / 7 ASN A  45
GLU A  69
TYR A  42
GLU A  52
 NAG  A 148 (-1.7A)
None
None
NAG  A 148 ( 4.0A)
 1.31A 4r87I-1bikA:
undetectable		 4r87I-1bikA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.48A 5i1nC-1bikA:
0.0		 5i1nC-1bikA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.25A 5i1nB-1bikA:
0.0		 5i1nB-1bikA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.38A 5i1oC-1bikA:
undetectable		 5i1oC-1bikA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.27A 5i1oA-1bikA:
undetectable		 5i1oA-1bikA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.33A 5i1pA-1bikA:
0.0		 5i1pA-1bikA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bik BIKUNIN
(Homo
sapiens) 		3 / 3 ALA A  80
ASN A  83
LEU A  84
 None
 0.35A 5i1pD-1bikA:
undetectable		 5i1pD-1bikA:
18.75