SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1biy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 LEU A 434
LEU A 589
PHE A 487
LEU A 571
HIS A 458
 None
 1.34A 1kt5A-1biyA:
0.0		 1kt5A-1biyA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ASP A 546
LYS A 416
ARG A 428
 None
 1.10A 1ra8A-1biyA:
undetectable		 1ra8A-1biyA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.42A 1rqpA-1biyA:
2.2		 1rqpA-1biyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.42A 1rqpB-1biyA:
0.5		 1rqpB-1biyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.44A 1rqpC-1biyA:
2.2		 1rqpC-1biyA:
18.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 THR A 430
PRO A 593
TYR A 660
 None
 0.28A 2dxrA-1biyA:
41.0		 2dxrA-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 8 TYR A 433
GLY A 525
GLY A 466
THR A 464
ALA A 465
 FE  A 691 (-4.2A)
None
CO3  A 693 (-3.5A)
CO3  A 693 (-4.3A)
CO3  A 693 (-3.5A)
 1.38A 2ej3C-1biyA:
0.0		 2ej3C-1biyA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 6 TYR A 189
GLY A 204
ASP A 205
ASN A 113
 None
 1.15A 2g72A-1biyA:
undetectable		 2g72A-1biyA:
18.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 LEU A 651
TYR A 660
GLY A 662
 None
 0.55A 2ocuA-1biyA:
54.8		 2ocuA-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.46A 2v7uC-1biyA:
2.3		 2v7uC-1biyA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.45A 2v7uA-1biyA:
2.3		 2v7uA-1biyA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1300_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.46A 2v7uB-1biyA:
2.3		 2v7uB-1biyA:
19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 PRO A 593
GLU A 659
TYR A 660
 None
 0.59A 2zmbA-1biyA:
54.5		 2zmbA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 THR A 377
VAL A 516
GLY A 525
THR A 527
 None
 1.04A 3cflA-1biyA:
41.1		 3cflA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 THR A 430
VAL A 591
GLY A 662
THR A 663
 None
 0.57A 3cflA-1biyA:
41.1		 3cflA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 GLU A 659
GLY A 662
THR A 663
GLU A 664
 None
 1.28A 3e9xA-1biyA:
41.0		 3e9xA-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 TYR A 665
TYR A 433
GLY A 397
 None
FE  A 691 (-4.2A)
None
 0.64A 3eteB-1biyA:
undetectable
3eteD-1biyA:
undetectable
3eteF-1biyA:
undetectable		 3eteB-1biyA:
21.62
3eteD-1biyA:
21.62
3eteF-1biyA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 LEU A 680
ASP A 378
LYS A 673
LEU A 394
GLY A 403
 None
 1.25A 3glqA-1biyA:
undetectable		 3glqA-1biyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 LEU A 680
ASP A 378
LYS A 673
LEU A 394
GLY A 403
 None
 1.23A 3glqB-1biyA:
undetectable		 3glqB-1biyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 7 VAL A 149
LYS A 151
TRP A 125
PRO A 144
 None
 1.30A 3hs4A-1biyA:
undetectable		 3hs4A-1biyA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 PRO A 593
TYR A 660
GLY A 662
THR A 663
 None
 0.29A 3ib0A-1biyA:
55.3		 3ib0A-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 PRO A 429
THR A 430
GLY A 662
THR A 663
 None
 0.58A 3ib1A-1biyA:
40.7		 3ib1A-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 GLY A 432
VAL A 591
GLY A 662
THR A 663
 None
 0.49A 3ib2A-1biyA:
40.9		 3ib2A-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 4 SER A 114
GLY A 147
GLU A 140
 None
 0.70A 3raeA-1biyA:
0.0
3raeC-1biyA:
1.1		 3raeA-1biyA:
22.55
3raeC-1biyA:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		7 / 7 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
THR A 663
 None
 0.60A 3tajA-1biyA:
40.9		 3tajA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 PRO A 429
THR A 430
LEU A 651
 None
 0.48A 3ttrA-1biyA:
41.0		 3ttrA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 5 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
 None
 0.46A 3u8qA-1biyA:
41.1		 3u8qA-1biyA:
91.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_1
(MNMC2)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 GLU A 413
ASP A 643
ASP A 395
GLU A 550
 None
None
FE  A 691 (-2.5A)
None
 1.36A 3vywB-1biyA:
1.6		 3vywB-1biyA:
18.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		6 / 6 GLY A 432
VAL A 591
PRO A 593
GLY A 662
GLU A 664
TYR A 665
 None
 0.74A 4dxuA-1biyA:
55.1		 4dxuA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		9 / 9 GLU A 431
GLY A 432
VAL A 591
PRO A 593
PRO A 655
GLU A 659
TYR A 660
GLY A 662
TYR A 665
 None
 0.73A 4fimA-1biyA:
55.1		 4fimA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		6 / 6 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
 None
 0.44A 4fjpA-1biyA:
55.3		 4fjpA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		7 / 7 THR A 430
GLY A 432
VAL A 591
PRO A 593
ASN A 594
TYR A 660
GLY A 662
 None
 0.50A 4forA-1biyA:
55.1		 4forA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 PRO A 251
TYR A 319
GLY A 321
 None
 0.38A 4g2zA-1biyA:
55.2		 4g2zA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 PRO A 593
TYR A 660
GLY A 662
 None
 0.27A 4g2zA-1biyA:
55.2		 4g2zA-1biyA:
91.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 7 ILE A 127
HIS A 246
ALA A 248
TYR A 324
ALA A 327
 None
 0.34A 4g77A-1biyA:
55.5		 4g77A-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		6 / 7 ILE A 469
LEU A 473
HIS A 588
ALA A 590
VAL A 591
TYR A 665
 None
 0.58A 4g77A-1biyA:
55.5		 4g77A-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		6 / 7 LEU A 473
HIS A 588
ALA A 590
VAL A 591
TYR A 665
ALA A 668
 None
 0.60A 4g77A-1biyA:
55.5		 4g77A-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 5 THR A 430
GLY A 432
VAL A 591
PRO A 593
TYR A 660
 None
 0.37A 4grkA-1biyA:
55.3		 4grkA-1biyA:
91.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 8 PHE A 152
VAL A 206
ASP A 205
ALA A  96
 None
 0.92A 4m48A-1biyA:
0.0		 4m48A-1biyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 5 SER A 480
ALA A 482
PHE A 486
GLU A 485
 None
 0.95A 4m93B-1biyA:
undetectable
4m93C-1biyA:
undetectable		 4m93B-1biyA:
15.82
4m93C-1biyA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 VAL A 540
ALA A 541
GLY A 453
SER A 490
GLY A 538
 None
 1.21A 4mm5A-1biyA:
0.0		 4mm5A-1biyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 VAL A 540
ALA A 541
GLY A 453
SER A 490
GLY A 538
 None
 1.18A 4mmbA-1biyA:
0.0		 4mmbA-1biyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 VAL A 540
ALA A 541
GLY A 453
SER A 490
GLY A 538
 None
 1.15A 4mmdB-1biyA:
undetectable		 4mmdB-1biyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 VAL A 540
ALA A 541
GLY A 453
SER A 490
GLY A 538
 None
 1.18A 4mmeA-1biyA:
0.0		 4mmeA-1biyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 VAL A 540
ALA A 541
GLY A 453
SER A 490
GLY A 538
 None
 1.16A 4mmeB-1biyA:
0.0		 4mmeB-1biyA:
22.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 6 ASP A 378
VAL A 461
ASP A 462
SER A 676
 None
 0.88A 4nedA-1biyA:
41.1		 4nedA-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ASN A   5
ASP A  55
ASP A 261
 None
 0.74A 4obwD-1biyA:
undetectable		 4obwD-1biyA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ASP A 462
TYR A 398
TRP A 467
 None
 1.38A 4p7nA-1biyA:
undetectable		 4p7nA-1biyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 ASP A 379
LEU A 383
GLU A 353
GLU A 388
ASP A 513
 None
 1.00A 4xe5A-1biyA:
0.4		 4xe5A-1biyA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.45A 5i1nC-1biyA:
0.0		 5i1nC-1biyA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.30A 5i1nB-1biyA:
0.0		 5i1nB-1biyA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.32A 5i1oC-1biyA:
0.0		 5i1oC-1biyA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.34A 5i1oA-1biyA:
0.0		 5i1oA-1biyA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.31A 5i1pA-1biyA:
0.0		 5i1pA-1biyA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.33A 5i1pD-1biyA:
0.0		 5i1pD-1biyA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 PRO A 311
ARG A 309
GLU A 682
 None
 0.90A 5j6hA-1biyA:
0.0		 5j6hA-1biyA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 7 LEU A 299
PHE A 300
GLU A  80
ASP A 302
 None
 1.04A 5n5dA-1biyA:
undetectable		 5n5dA-1biyA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 7 LEU A 325
GLY A  61
SER A 322
LEU A 318
ALA A 317
 None
 1.20A 5o96C-1biyA:
undetectable		 5o96C-1biyA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		3 / 3 LYS A 357
LYS A 637
SER A 634
 None
 1.36A 5odiA-1biyA:
undetectable		 5odiA-1biyA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 4 LEU A 687
LEU A 318
SER A 322
ALA A 317
 None
 1.13A 5uunA-1biyA:
0.3		 5uunA-1biyA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 ASP A 315
ALA A  79
ILE A 310
GLY A 321
SER A 316
 None
 1.25A 6awoA-1biyA:
0.0		 6awoA-1biyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 ASP A 315
ALA A  79
ILE A 310
GLY A 321
SER A 316
 None
 1.25A 6awqA-1biyA:
0.0		 6awqA-1biyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 9 LEU A 298
ASP A 302
SER A 193
GLY A 191
PHE A 190
 None
 1.15A 6ebpA-1biyA:
0.0		 6ebpA-1biyA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		5 / 12 GLU A 211
LEU A 106
ALA A  94
LEU A 232
ARG A 236
 None
 1.22A 6ew0F-1biyA:
undetectable		 6ew0F-1biyA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 5 LEU A 451
LEU A 589
THR A 577
ARG A 566
 None
 0.92A 6ew0F-1biyA:
0.0		 6ew0F-1biyA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 6 LEU A 451
LEU A 589
THR A 577
ARG A 566
 None
 0.92A 6ew0G-1biyA:
undetectable		 6ew0G-1biyA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1biy LACTOFERRIN
(Bubalus
bubalis) 		4 / 6 MET A 129
ARG A 121
TRP A 125
ALA A 123
 None
CO3  A 692 (-4.2A)
None
CO3  A 692 (-3.2A)
 1.19A 6fosB-1biyA:
undetectable		 6fosB-1biyA:
6.91