SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 7 LEU A 276
VAL A 279
TYR A 286
LEU A 325
 None
 0.77A 1cqpA-1bjnA:
2.0
1cqpB-1bjnA:
2.0		 1cqpA-1bjnA:
21.61
1cqpB-1bjnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 199
ILE A 338
SER A 296
ASN A 151
 LLP  A 198 ( 4.3A)
None
None
None
 1.25A 1h7xA-1bjnA:
undetectable		 1h7xA-1bjnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 199
ILE A 338
SER A 296
ASN A 151
 LLP  A 198 ( 4.3A)
None
None
None
 1.25A 1h7xB-1bjnA:
undetectable		 1h7xB-1bjnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 199
ILE A 338
SER A 296
ASN A 151
 LLP  A 198 ( 4.3A)
None
None
None
 1.26A 1h7xC-1bjnA:
undetectable		 1h7xC-1bjnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 199
ILE A 338
SER A 296
ASN A 151
 LLP  A 198 ( 4.3A)
None
None
None
 1.26A 1h7xD-1bjnA:
undetectable		 1h7xD-1bjnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A   4
GLY A 321
ALA A 320
HIS A 323
 None
 0.97A 1wmqB-1bjnA:
0.0		 1wmqB-1bjnA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A   4
GLY A 321
ALA A 320
HIS A 323
 None
 0.98A 1wpuA-1bjnA:
0.0		 1wpuA-1bjnA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A   4
GLY A 321
ALA A 320
HIS A 323
 None
 0.98A 1wrqA-1bjnA:
0.0		 1wrqA-1bjnA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A   4
GLY A 321
ALA A 320
HIS A 323
 None
 1.00A 1wrqB-1bjnA:
undetectable		 1wrqB-1bjnA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 5 TYR A 339
SER A 337
THR A 153
ASN A 151
 LLP  A 198 ( 3.5A)
None
LLP  A 198 ( 3.5A)
None
 1.40A 1yvpA-1bjnA:
undetectable		 1yvpA-1bjnA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 11 GLN A  79
LEU A 231
VAL A  83
ALA A  82
LEU A  85
 None
 1.35A 2c12F-1bjnA:
0.0		 2c12F-1bjnA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A  22
GLU A  25
LEU A  26
GLY A 201
LEU A  14
 None
 1.12A 2jfaB-1bjnA:
undetectable		 2jfaB-1bjnA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 ARG A  58
ILE A 179
GLY A 201
SER A 249
PHE A 253
 None
 1.00A 2oc8A-1bjnA:
0.0		 2oc8A-1bjnA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 5 LEU A  60
ILE A 200
SER A 249
GLY A 250
 None
 1.01A 2otfA-1bjnA:
undetectable		 2otfA-1bjnA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 7 TYR A 193
VAL A 208
TYR A 228
ILE A  87
 None
 1.08A 2x45B-1bjnA:
undetectable		 2x45B-1bjnA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 7 TYR A 193
VAL A 208
TYR A 228
ILE A  87
 None
 1.08A 2x45C-1bjnA:
undetectable		 2x45C-1bjnA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		3 / 3 MET A 237
GLU A  54
ASP A  56
 None
 1.12A 3a25A-1bjnA:
2.0		 3a25A-1bjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 9 VAL A 331
GLY A 327
LYS A 326
THR A 153
GLY A 156
 None
None
None
LLP  A 198 ( 3.5A)
None
 1.11A 3bjwG-1bjnA:
0.0		 3bjwG-1bjnA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		3 / 3 VAL A 131
LYS A 132
HIS A 147
 None
 0.93A 3elzA-1bjnA:
0.0		 3elzA-1bjnA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 294
ARG A 293
TRP A 137
GLU A 161
 None
 1.42A 3galA-1bjnA:
undetectable		 3galA-1bjnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 5 VAL A  63
ILE A 207
MET A 237
ARG A 211
 None
 1.50A 3pyyB-1bjnA:
undetectable		 3pyyB-1bjnA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 8 TYR A 148
LEU A 139
VAL A 169
VAL A 171
 None
 0.90A 4em2A-1bjnA:
0.0		 4em2A-1bjnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 8 SER A   8
SER A   9
THR A 153
MET A 334
 None
None
LLP  A 198 ( 3.5A)
None
 1.01A 4fo4A-1bjnA:
undetectable		 4fo4A-1bjnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A  50
PHE A 253
LEU A  61
VAL A  63
VAL A 252
 None
 1.13A 4ib4A-1bjnA:
undetectable		 4ib4A-1bjnA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		3 / 3 GLU A 316
ARG A 360
HIS A 361
 None
 0.85A 4kf9A-1bjnA:
0.0		 4kf9A-1bjnA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		4 / 7 PRO A 163
VAL A 171
ALA A 173
PHE A 175
 None
 0.80A 4lb2A-1bjnA:
undetectable		 4lb2A-1bjnA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 251
LEU A 180
ASN A 259
 None
 0.67A 4otwA-1bjnA:
0.0		 4otwA-1bjnA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A 345
ILE A 338
ALA A 336
PHE A 302
VAL A 300
 None
 1.11A 4u8yB-1bjnA:
0.0		 4u8yB-1bjnA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 ASN A 299
ARG A 129
ASP A  98
ALA A 103
SER A 177
 None
None
None
None
LLP  A 198 ( 3.7A)
 0.98A 4uroC-1bjnA:
undetectable		 4uroC-1bjnA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		6 / 12 GLY A  74
GLY A  78
ILE A 207
ASP A 174
SER A 176
ALA A 196
 None
None
None
LLP  A 198 ( 3.0A)
LLP  A 198 ( 3.9A)
None
 1.39A 5l0zA-1bjnA:
undetectable		 5l0zA-1bjnA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 248
ALA A 245
LEU A  14
 None
 0.55A 5uunB-1bjnA:
0.0		 5uunB-1bjnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1bjn PHOSPHOSERINE
AMINOTRANSFERASE
(Escherichia
coli) 		5 / 12 ARG A  58
ILE A 179
GLY A 201
SER A 249
PHE A 253
 None
 1.01A 6c2mA-1bjnA:
0.0		 6c2mA-1bjnA:
13.25