SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		5 / 12 PHE A 144
ILE A 169
THR A 121
LEU A 123
VAL A 186
 None
 1.25A 2jn3A-1bjxA:
undetectable		 2jn3A-1bjxA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		4 / 6 GLY A 142
PHE A 155
LYS A 119
THR A 121
 None
 1.01A 2m2oB-1bjxA:
undetectable		 2m2oB-1bjxA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		3 / 3 VAL A 133
GLU A 130
GLU A 134
 None
 0.68A 2nv4A-1bjxA:
0.0		 2nv4A-1bjxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		3 / 3 ALA A 139
VAL A 138
GLN A 216
 None
 0.61A 3of4B-1bjxA:
undetectable		 3of4B-1bjxA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		5 / 10 VAL A 175
PHE A 176
PHE A 155
ILE A 169
GLY A 168
 None
 1.20A 3t3rD-1bjxA:
0.0		 3t3rD-1bjxA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		4 / 6 ALA A 161
ASP A 164
LEU A 209
LYS A 213
 None
 1.00A 4ot2A-1bjxA:
undetectable		 4ot2A-1bjxA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		5 / 12 GLY A 185
VAL A 203
LEU A 208
PHE A 144
ILE A 169
 None
 1.18A 4pd5A-1bjxA:
undetectable		 4pd5A-1bjxA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		5 / 12 GLY A 185
VAL A 203
LEU A 208
PHE A 144
ILE A 169
 None
 1.20A 4pd9A-1bjxA:
0.0		 4pd9A-1bjxA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens) 		4 / 7 ILE A 212
GLN A 216
GLU A 137
VAL A 140
 None
 1.12A 6j20A-1bjxA:
undetectable		 6j20A-1bjxA:
14.53