SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bkb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		5 / 12 ALA A  81
ASP A  95
ILE A 135
ARG A  97
ILE A 134
 None
 0.91A 3n3iA-1bkbA:
undetectable		 3n3iA-1bkbA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		5 / 9 ALA A  81
ASP A  95
ILE A 102
ILE A 135
ILE A  91
 None
 1.02A 3s45A-1bkbA:
undetectable		 3s45A-1bkbA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		5 / 9 ALA A  81
ASP A  95
ILE A 102
ILE A 135
ILE A  91
 None
 0.86A 3s53A-1bkbA:
undetectable		 3s53A-1bkbA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		5 / 12 ALA A  81
ASP A  95
ILE A 102
ILE A 135
ILE A  91
 None
 0.79A 3s56A-1bkbA:
undetectable		 3s56A-1bkbA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.51A 5qgjA-1bkbA:
0.0		 5qgjA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qglA-1bkbA:
0.0		 5qglA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qgmA-1bkbA:
0.0		 5qgmA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.48A 5qgnA-1bkbA:
0.0		 5qgnA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.55A 5qguA-1bkbA:
0.0		 5qguA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qgvA-1bkbA:
0.0		 5qgvA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.55A 5qgwA-1bkbA:
0.0		 5qgwA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qgxA-1bkbA:
0.0		 5qgxA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qgyA-1bkbA:
0.0		 5qgyA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qgzA-1bkbA:
0.0		 5qgzA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.55A 5qh0A-1bkbA:
0.0		 5qh0A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qh1A-1bkbA:
0.0		 5qh1A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.54A 5qh2A-1bkbA:
0.0		 5qh2A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qh3A-1bkbA:
0.0		 5qh3A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qh4A-1bkbA:
0.0		 5qh4A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.49A 5qh5A-1bkbA:
0.0		 5qh5A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qh6A-1bkbA:
0.0		 5qh6A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qh7A-1bkbA:
0.0		 5qh7A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qh9A-1bkbA:
0.0		 5qh9A-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.58A 5qhaA-1bkbA:
0.0		 5qhaA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.54A 5qhcA-1bkbA:
0.0		 5qhcA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.56A 5qheA-1bkbA:
0.0		 5qheA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.53A 5qhfA-1bkbA:
0.0		 5qhfA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.50A 5qhgA-1bkbA:
0.0		 5qhgA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		3 / 3 VAL A 137
VAL A 123
GLN A  82
 None
 0.52A 5qhhA-1bkbA:
0.0		 5qhhA-1bkbA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		4 / 7 VAL A  33
ARG A  31
VAL A  23
GLY A  54
 None
 0.97A 5x80C-1bkbA:
undetectable
5x80D-1bkbA:
undetectable		 5x80C-1bkbA:
20.12
5x80D-1bkbA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bkb TRANSLATION
INITIATION FACTOR 5A
(Pyrobaculum
aerophilum) 		4 / 7 ILE A  25
LEU A  63
ARG A  31
LEU A  17
 None
 0.96A 5zcpA-1bkbA:
undetectable
5zcpJ-1bkbA:
undetectable		 5zcpA-1bkbA:
12.88
5zcpJ-1bkbA:
17.04