SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bkh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 8 ILE A   9
LEU A  79
GLU A 109
ALA A 111
VAL A  39
 None
 1.21A 1a29A-1bkhA:
undetectable		 1a29A-1bkhA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 HIS A 314
LEU A 333
GLY A 300
VAL A 138
ALA A 139
 None
 1.15A 1axwA-1bkhA:
0.0		 1axwA-1bkhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 8 ALA A 193
LYS A 186
LEU A 189
LEU A 158
ALA A 154
 None
 1.38A 1e7cA-1bkhA:
0.0		 1e7cA-1bkhA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 GLN A 321
ILE A 352
HIS A 314
 None
 0.67A 1fm9A-1bkhA:
undetectable		 1fm9A-1bkhA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 8 THR A 355
PRO A 356
GLY A 357
THR A 361
 None
 0.67A 1h4oB-1bkhA:
undetectable		 1h4oB-1bkhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 GLN A 321
ILE A 352
HIS A 314
 None
 0.64A 1k74A-1bkhA:
undetectable		 1k74A-1bkhA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 8 THR A 355
PRO A 356
GLY A 357
THR A 361
 None
 0.69A 1oc3A-1bkhA:
2.1		 1oc3A-1bkhA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 8 ALA A  11
ILE A   9
ILE A 108
GLY A  49
ILE A 307
 None
 1.31A 1sh9A-1bkhA:
0.0		 1sh9A-1bkhA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 8 ALA A  51
ILE A  71
ILE A 108
ILE A  48
 None
 0.65A 1sh9A-1bkhA:
0.0		 1sh9A-1bkhA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 6 ALA A 287
GLU A 291
ILE A 295
LEU A 272
 None
 0.78A 1xvaA-1bkhA:
undetectable
1xvaB-1bkhA:
undetectable		 1xvaA-1bkhA:
23.98
1xvaB-1bkhA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 GLU A 256
ILE A 295
LEU A 297
SER A 254
ASN A 277
 None
 1.13A 2e7fA-1bkhA:
8.4		 2e7fA-1bkhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 GLY A 107
GLY A 308
LEU A 112
LEU A 113
LEU A  94
 None
 1.03A 2nyuB-1bkhA:
2.0		 2nyuB-1bkhA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 ASP A 204
THR A 242
PRO A 243
 None
 0.50A 2pynB-1bkhA:
undetectable		 2pynB-1bkhA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 ASP A 204
THR A 242
PRO A 243
 None
 0.52A 2q64B-1bkhA:
undetectable		 2q64B-1bkhA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 ASP A 204
THR A 242
PRO A 243
 None
 0.47A 2qakB-1bkhA:
undetectable		 2qakB-1bkhA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 11 SER A 106
LEU A 328
ILE A 274
ALA A 315
LEU A 358
 None
 1.39A 2v0mA-1bkhA:
undetectable		 2v0mA-1bkhA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 11 SER A 106
LEU A 328
ILE A 274
ALA A 315
LEU A 358
 None
 1.35A 2v0mD-1bkhA:
0.0		 2v0mD-1bkhA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 8 LEU A 142
ILE A 185
HIS A 181
ARG A 149
 None
 0.92A 3b9lA-1bkhA:
0.0		 3b9lA-1bkhA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 THR A 326
VAL A 138
PHE A 316
ILE A 274
THR A  52
 None
 1.39A 3em0A-1bkhA:
undetectable		 3em0A-1bkhA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 GLU A 364
GLU A  46
VAL A  14
ASP A  10
ILE A  12
 None
 1.45A 3jb3A-1bkhA:
3.2		 3jb3A-1bkhA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 LEU A 367
ARG A  38
GLY A 308
THR A 309
LEU A 362
 None
 1.11A 3okxB-1bkhA:
0.0		 3okxB-1bkhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 ILE A 274
GLY A 308
THR A 309
GLU A  50
THR A  52
 None
 1.20A 3r75A-1bkhA:
undetectable		 3r75A-1bkhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 ILE A 274
GLY A 308
THR A 309
GLU A  50
THR A  52
 None
 1.21A 3r75B-1bkhA:
undetectable		 3r75B-1bkhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 11 ILE A 274
GLY A 308
THR A 309
GLU A  50
THR A  52
 None
 1.20A 3r76A-1bkhA:
undetectable		 3r76A-1bkhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 11 ILE A 274
GLY A 308
THR A 309
GLU A  50
THR A  52
 None
 1.19A 3r76B-1bkhA:
undetectable		 3r76B-1bkhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 7 LEU A 360
ILE A 352
THR A 355
GLY A 357
 None
 0.95A 4eqlB-1bkhA:
1.1		 4eqlB-1bkhA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 7 ILE A 108
GLY A 308
ALA A 111
GLN A  32
 None
 0.97A 4g0uB-1bkhA:
2.3		 4g0uB-1bkhA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 6 LEU A 360
ILE A 352
THR A 355
GLY A 357
 None
 1.01A 4l39A-1bkhA:
1.2		 4l39A-1bkhA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 4 HIS A 163
ALA A 139
VAL A 138
GLU A 327
 None
 1.14A 4n6pA-1bkhA:
0.5		 4n6pA-1bkhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 9 ALA A 111
ILE A 307
GLY A 308
ILE A 274
ILE A  71
 None
 1.11A 4nptA-1bkhA:
0.0		 4nptA-1bkhA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 7 THR A  52
GLU A  50
GLY A 330
GLY A 305
 None
 0.72A 4rdxA-1bkhA:
undetectable		 4rdxA-1bkhA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 LEU A 128
LEU A 319
THR A 301
ALA A 287
ILE A 274
 None
 1.14A 4x1iD-1bkhA:
4.0		 4x1iD-1bkhA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 LEU A 128
LEU A 319
THR A 301
ALA A 287
ILE A 274
 None
 1.13A 4x1kD-1bkhA:
3.2		 4x1kD-1bkhA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 4 LEU A 310
ILE A 307
GLY A 359
ILE A  48
 None
 0.84A 5dzk3-1bkhA:
undetectable
5dzkm-1bkhA:
3.2		 5dzk3-1bkhA:
15.38
5dzkm-1bkhA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 5 ILE A 307
GLY A 359
ILE A  48
LEU A 310
 None
 0.86A 5dzki-1bkhA:
0.5
5dzkj-1bkhA:
2.2
5dzkx-1bkhA:
undetectable		 5dzki-1bkhA:
22.13
5dzkj-1bkhA:
22.13
5dzkx-1bkhA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		3 / 3 ASP A 178
VAL A 197
LEU A 215
 None
 0.68A 5e5jB-1bkhA:
0.0		 5e5jB-1bkhA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 LEU A 128
LEU A 319
THR A 301
ALA A 287
ILE A 274
 None
 1.17A 5eypB-1bkhA:
3.6		 5eypB-1bkhA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 ILE A 220
ARG A 196
PRO A 245
LEU A 222
GLY A 219
 None
 1.20A 5k7uA-1bkhA:
undetectable		 5k7uA-1bkhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 VAL A  36
LEU A  37
ALA A  76
GLY A  47
LEU A 362
 None
 1.03A 5kirA-1bkhA:
0.0		 5kirA-1bkhA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		4 / 5 VAL A 175
LEU A 215
CYH A 212
ASP A 204
 None
 1.05A 5vcvA-1bkhA:
undetectable		 5vcvA-1bkhA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 1bkh MUCONATE LACTONIZING
ENZYME
(Pseudomonas
putida) 		5 / 12 LEU A 128
LEU A 319
THR A 301
ALA A 287
ILE A 274
 None
 1.21A 5xiwD-1bkhA:
2.8		 5xiwD-1bkhA:
14.33