SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ble'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 LEU A  83
LEU A  19
ILE A  90
LEU A 146
PRO A 147
 None
 0.97A 1hrkA-1bleA:
3.2		 1hrkA-1bleA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 LEU A  83
LEU A  19
ILE A  90
LEU A 146
PRO A 147
 None
 1.01A 2po7A-1bleA:
2.1		 2po7A-1bleA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 LEU A  83
LEU A  19
ILE A  90
LEU A 146
PRO A 147
 None
 0.98A 2po7B-1bleA:
0.8		 2po7B-1bleA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 SER A  92
ASP A 127
GLN A 126
ALA A 130
THR A 133
 None
 1.14A 3a35A-1bleA:
0.0		 3a35A-1bleA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 SER A  92
ASP A 127
GLN A 126
ALA A 130
THR A 133
 None
 1.12A 3a35B-1bleA:
undetectable		 3a35B-1bleA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 SER A  92
ASP A 127
GLN A 126
ALA A 130
THR A 133
 None
 1.11A 3a3bA-1bleA:
undetectable		 3a3bA-1bleA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1ble FRUCTOSE PERMEASE
(Bacillus
subtilis) 		4 / 4 ILE A  48
ILE A  38
ARG A  44
LEU A  83
 None
 1.14A 5dzkh-1bleA:
0.0
5dzkn-1bleA:
0.0
5dzkv-1bleA:
undetectable		 5dzkh-1bleA:
22.77
5dzkn-1bleA:
22.77
5dzkv-1bleA:
2.41