SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RBP_A_RTLA183_0 (PLASMA RETINOL-BINDING PROTEIN PRECURSOR)	1bm8	TRANSCRIPTION FACTOR MBP1 (Saccharomyces cerevisiae)	5 / 12	LEU A 80 ALA A 43 ALA A 42 VAL A 34 LEU A 99	None	1.18A	1rbpA-1bm8A: undetectable	1rbpA-1bm8A: 23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XR2_B_C2FB1201_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1bm8	TRANSCRIPTION FACTOR MBP1 (Saccharomyces cerevisiae)	4 / 8	SER A 11 ARG A 9 TRP A 77 GLU A 64	None	1.22A	1xr2B-1bm8A: 0.0	1xr2B-1bm8A: 8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RLB_B_VIBB187_1 (THIT)	1bm8	TRANSCRIPTION FACTOR MBP1 (Saccharomyces cerevisiae)	5 / 12	TRP A 77 GLU A 17 TYR A 10 GLY A 69 VAL A 13	None	1.49A	3rlbB-1bm8A: undetectable	3rlbB-1bm8A: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_D_ACTD305_0 (GLUTATHIONE TRANSFERASE GTE1)	1bm8	TRANSCRIPTION FACTOR MBP1 (Saccharomyces cerevisiae)	4 / 4	ILE A 39 LEU A 40 LYS A 41 ASN A 35	None	1.19A	4g19D-1bm8A: 0.0	4g19D-1bm8A: 17.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RBP_A_RTLA183_0","PLASMA RETINOL-BINDING PROTEIN PRECURSOR","1bm8","TRANSCRIPTION FACTOR MBP1","Saccharomyces cerevisiae",5,"LEU A  80;ALA A  43;ALA A  42;VAL A  34;LEU A  99","None","1.18A","1rbpA-1bm8A:undetectable","1rbpA-1bm8A:23.57"],["1XR2_B_C2FB1201_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1bm8","TRANSCRIPTION FACTOR MBP1","Saccharomyces cerevisiae",4,"SER A  11;ARG A   9;TRP A  77;GLU A  64","None","1.22A","1xr2B-1bm8A:0.0","1xr2B-1bm8A:8.23"],["3RLB_B_VIBB187_1","THIT","1bm8","TRANSCRIPTION FACTOR MBP1","Saccharomyces cerevisiae",5,"TRP A  77;GLU A  17;TYR A  10;GLY A  69;VAL A  13","None","1.49A","3rlbB-1bm8A:undetectable","3rlbB-1bm8A:19.85"],["4G19_D_ACTD305_0","GLUTATHIONE TRANSFERASE GTE1","1bm8","TRANSCRIPTION FACTOR MBP1","Saccharomyces cerevisiae",4,"ILE A  39;LEU A  40;LYS A  41;ASN A  35","None","1.19A","4g19D-1bm8A:0.0","4g19D-1bm8A:17.53"]]