SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		4 / 7 ARG C 219
ILE C 270
PHE C 241
GLU C 198
 None
 1.42A 2nsiA-1bmlC:
0.0
2nsiB-1bmlC:
0.0		 2nsiA-1bmlC:
20.17
2nsiB-1bmlC:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		4 / 7 ARG C 248
TYR C 243
LEU C 235
TYR C  97
 None
 1.21A 4f8yC-1bmlC:
undetectable
4f8yD-1bmlC:
undetectable		 4f8yC-1bmlC:
20.39
4f8yD-1bmlC:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		5 / 12 LEU C 137
LYS C  76
VAL C 125
TYR C 117
LEU C  18
 None
 1.41A 5cyqA-1bmlC:
undetectable		 5cyqA-1bmlC:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		4 / 6 ASP C 227
ILE C 230
ARG C 232
TYR C 243
 None
 1.46A 5igyA-1bmlC:
0.0		 5igyA-1bmlC:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		3 / 3 SER C 105
ALA C 104
THR C  25
 None
 0.63A 5n0xB-1bmlC:
0.0		 5n0xB-1bmlC:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1bml STREPTOKINASE
(Streptococcus
dysgalactiae) 		4 / 5 ALA C 107
VAL C 141
LYS C  76
ILE C  83
 None
 0.97A 5of1A-1bmlC:
0.0		 5of1A-1bmlC:
14.55