SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		3 / 3 ALA A  17
VAL A 171
TRP A 120
 None
 0.97A 1av2A-1bnlA:
undetectable
1av2B-1bnlA:
undetectable		 1av2A-1bnlA:
11.21
1av2B-1bnlA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		3 / 3 ALA A  17
VAL A 171
TRP A 120
 None
 0.96A 1c4dC-1bnlA:
undetectable
1c4dD-1bnlA:
undetectable		 1c4dC-1bnlA:
11.21
1c4dD-1bnlA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		4 / 8 VAL A  13
LEU A  42
HIS A   3
VAL A   9
 None
None
ZN  A 179 (-3.2A)
None
 0.91A 1jtvA-1bnlA:
undetectable		 1jtvA-1bnlA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		5 / 12 GLY A  22
ALA A 145
THR A 146
ALA A 163
HIS A 166
 None
 1.06A 2gluA-1bnlA:
undetectable		 2gluA-1bnlA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		4 / 8 LEU A  86
VAL A 119
ILE A 100
PHE A  49
 None
 0.83A 2weyB-1bnlA:
undetectable		 2weyB-1bnlA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		3 / 3 TRP A 120
ALA A  17
VAL A 171
 None
 0.98A 3l8lC-1bnlA:
undetectable
3l8lD-1bnlA:
undetectable		 3l8lC-1bnlA:
11.21
3l8lD-1bnlA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		4 / 5 ARG A  62
PHE A 178
PRO A   8
LEU A  10
 None
 1.49A 3tgvC-1bnlA:
0.0		 3tgvC-1bnlA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		4 / 8 ILE A 100
PHE A  49
TRP A  83
GLY A  92
 None
 0.77A 4fgjA-1bnlA:
undetectable
4fgjB-1bnlA:
undetectable		 4fgjA-1bnlA:
22.22
4fgjB-1bnlA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		3 / 3 HIS A 121
VAL A 108
LEU A 152
 None
 0.76A 4m2vA-1bnlA:
0.0		 4m2vA-1bnlA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 1bnl COLLAGEN XVIII
(Homo
sapiens) 		5 / 12 LEU A 172
GLY A 154
LEU A 153
ALA A 149
VAL A 108
 None
 1.10A 4wnwB-1bnlA:
undetectable		 4wnwB-1bnlA:
18.07