SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQU_A_ESTA304_1
(ESTROGEN
SULFOTRANSFERASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		10 / 11 ARG A  23
TYR A  81
CYH A  84
ASN A  86
LYS A 106
HIS A 108
PHE A 142
SER A 148
TYR A 149
MET A 247
 None
VO4  A 302 ( 4.9A)
None
None
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
None
None
 0.49A 1aquA-1bo6A:
45.2
1aquB-1bo6A:
44.5		 1aquA-1bo6A:
100.00
1aquB-1bo6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQU_B_ESTB303_1
(ESTROGEN
SULFOTRANSFERASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		10 / 10 ASP A  21
ARG A  23
TYR A  81
CYH A  84
ASN A  86
LYS A 106
HIS A 108
PHE A 142
TYR A 149
MET A 247
 None
None
VO4  A 302 ( 4.9A)
None
None
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
None
 0.49A 1aquB-1bo6A:
44.5		 1aquB-1bo6A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 8 VAL A  31
LEU A 109
MET A  20
VAL A  18
 None
 1.09A 1fduB-1bo6A:
2.1		 1fduB-1bo6A:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMJ_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		5 / 11 TYR A  81
LEU A  89
LYS A 106
HIS A 108
PHE A 255
 VO4  A 302 ( 4.9A)
None
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
A3P  A 301 ( 4.6A)
 1.06A 1fmjA-1bo6A:
33.7		 1fmjA-1bo6A:
30.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		3 / 4 VAL A 135
TRP A 264
TRP A 172
 None
 1.35A 1gmkC-1bo6A:
undetectable
1gmkD-1bo6A:
undetectable		 1gmkC-1bo6A:
3.92
1gmkD-1bo6A:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 4 LEU A 143
PRO A 152
LEU A 144
ARG A 257
 None
None
None
A3P  A 301 (-4.0A)
 1.19A 1hrkB-1bo6A:
undetectable		 1hrkB-1bo6A:
21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		6 / 10 PHE A  24
PRO A  47
LYS A  48
LYS A 106
HIS A 108
MET A 248
 None
VO4  A 302 (-4.2A)
A3P  A 301 ( 2.9A)
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
None
 0.67A 2d06A-1bo6A:
40.5		 2d06A-1bo6A:
49.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		6 / 10 PHE A  24
PRO A  47
LYS A 106
HIS A 108
PHE A 142
MET A 248
 None
VO4  A 302 (-4.2A)
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
 0.88A 2d06A-1bo6A:
40.5		 2d06A-1bo6A:
49.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		6 / 10 PHE A  24
PRO A  47
HIS A 108
PHE A 142
TYR A 240
MET A 248
 None
VO4  A 302 (-4.2A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
None
 0.87A 2d06B-1bo6A:
40.4		 2d06B-1bo6A:
49.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		6 / 10 PRO A  47
LYS A 106
HIS A 108
PHE A 142
TYR A 240
MET A 248
 VO4  A 302 (-4.2A)
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
None
 0.81A 2d06B-1bo6A:
40.4		 2d06B-1bo6A:
49.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		5 / 11 TYR A 169
PRO A 168
PHE A  24
VAL A  11
TYR A 149
 None
 1.45A 2fl5A-1bo6A:
0.0
2fl5B-1bo6A:
undetectable
2fl5F-1bo6A:
undetectable		 2fl5A-1bo6A:
21.88
2fl5B-1bo6A:
17.63
2fl5F-1bo6A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 4 LEU A 143
PRO A 152
LEU A 144
ARG A 257
 None
None
None
A3P  A 301 (-4.0A)
 1.09A 2hrcA-1bo6A:
0.0		 2hrcA-1bo6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 4 LEU A 143
PRO A 152
LEU A 144
ARG A 257
 None
None
None
A3P  A 301 (-4.0A)
 1.20A 2hrcB-1bo6A:
undetectable		 2hrcB-1bo6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 4 LEU A 143
PRO A 152
LEU A 144
ARG A 257
 None
None
None
A3P  A 301 (-4.0A)
 1.19A 2pnjB-1bo6A:
undetectable		 2pnjB-1bo6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 PRO A 152
LEU A 144
ARG A 257
 None
None
A3P  A 301 (-4.0A)
 0.78A 3aqiA-1bo6A:
undetectable		 3aqiA-1bo6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		3 / 3 ALA A 271
ARG A 273
LYS A 133
 None
 1.12A 3kp5B-1bo6A:
0.0		 3kp5B-1bo6A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		5 / 10 ILE A  75
THR A  52
TRP A  53
ILE A 104
ILE A  43
 None
A3P  A 301 (-3.7A)
A3P  A 301 (-3.5A)
None
None
 1.38A 3kpbD-1bo6A:
undetectable		 3kpbD-1bo6A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 PHE A 210
ILE A  43
VAL A  58
TYR A  62
 None
 1.07A 3p6hA-1bo6A:
undetectable		 3p6hA-1bo6A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 MET A 196
VAL A  57
TRP A  53
GLU A 203
 None
None
A3P  A 301 (-3.5A)
None
 1.41A 4jseA-1bo6A:
0.0
4jseB-1bo6A:
0.0		 4jseA-1bo6A:
19.72
4jseB-1bo6A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 7 GLU A 203
MET A 196
VAL A  57
TRP A  53
 None
None
None
A3P  A 301 (-3.5A)
 1.45A 4jseA-1bo6A:
0.0
4jseB-1bo6A:
0.0		 4jseA-1bo6A:
19.72
4jseB-1bo6A:
19.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		5 / 9 CYH A  84
LYS A 106
HIS A 108
PHE A 142
MET A 248
 None
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
 0.62A 4jvlA-1bo6A:
44.6		 4jvlA-1bo6A:
77.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		4 / 9 LYS A 106
PHE A 255
ILE A 146
MET A 248
 VO4  A 302 (-3.0A)
A3P  A 301 ( 4.6A)
None
None
 1.06A 4jvlA-1bo6A:
44.6		 4jvlA-1bo6A:
77.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_B_ESTB302_1
(ESTROGEN
SULFOTRANSFERASE)		 1bo6 ESTROGEN
SULFOTRANSFERASE
(Mus
musculus) 		5 / 9 CYH A  84
LYS A 106
HIS A 108
PHE A 142
MET A 248
 None
VO4  A 302 (-3.0A)
VO4  A 302 (-3.9A)
VO4  A 302 ( 4.6A)
None
 0.67A 4jvlB-1bo6A:
44.3		 4jvlB-1bo6A:
77.29