SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 TRP A  91
VAL A 100
TRP A 102
 None
 1.26A 1c4dC-1bolA:
undetectable
1c4dD-1bolA:
undetectable		 1c4dC-1bolA:
10.87
1c4dD-1bolA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 THR A 115
THR A  18
PRO A  22
 None
 0.88A 1fjaC-1bolA:
undetectable		 1fjaC-1bolA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 THR A 115
THR A  18
PRO A  22
 None
 0.88A 1fjaD-1bolA:
undetectable		 1fjaD-1bolA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		4 / 6 TRP A  49
HIS A  46
ASN A  94
GLN A  95
 None
 1.19A 2ez7A-1bolA:
undetectable		 2ez7A-1bolA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		4 / 8 TYR A  57
GLU A 105
HIS A  46
GLY A  47
 None
 1.02A 2ha4A-1bolA:
undetectable		 2ha4A-1bolA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		4 / 7 TYR A  57
GLU A 105
HIS A  46
GLY A  47
 None
 1.07A 2ha4B-1bolA:
undetectable		 2ha4B-1bolA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 TRP A  91
VAL A 100
TRP A 102
 None
 0.94A 3zq8C-1bolA:
undetectable
3zq8D-1bolA:
undetectable		 3zq8C-1bolA:
10.87
3zq8D-1bolA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 TYR A  84
SER A  74
TRP A 102
 None
 0.87A 5n8jB-1bolA:
0.0		 5n8jB-1bolA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 TYR A  84
SER A  74
TRP A 102
 None
 0.85A 5n8jA-1bolA:
0.0		 5n8jA-1bolA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1bol PROTEIN
(RIBONUCLEASE RH)
(Rhizopus
niveus) 		3 / 3 TYR A  84
SER A  74
TRP A 102
 None
 0.84A 5n8jD-1bolA:
0.0		 5n8jD-1bolA:
21.37