SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 8 ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.69A 1hshD-1bouB:
0.0		 1hshD-1bouB:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B  91
VAL B  96
TRP B 143
 None
 0.73A 1qw6A-1bouB:
0.0		 1qw6A-1bouB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B  91
VAL B  96
TRP B 143
 None
 0.85A 1qwcA-1bouB:
0.0		 1qwcA-1bouB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 10 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.99A 1sdtA-1bouB:
undetectable		 1sdtA-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B  91
VAL B  96
TRP B 143
 None
 0.80A 1vagA-1bouB:
0.0		 1vagA-1bouB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 110
ILE B 248
MET B 245
PHE B 150
ILE B  75
 None
 1.35A 1xotA-1bouB:
undetectable		 1xotA-1bouB:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 5 VAL B 152
ASN B  59
VAL B 244
ILE B 248
 None
FE  B 501 (-3.2A)
None
None
 0.98A 1z2bC-1bouB:
undetectable		 1z2bC-1bouB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 5 ILE B 214
ILE B 136
MET B 193
LEU B 288
 None
 0.91A 1zgyA-1bouB:
undetectable		 1zgyA-1bouB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B  91
VAL B  96
TRP B 143
 None
 0.80A 1zviA-1bouB:
0.0		 1zviA-1bouB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 SER A  43
GLU A  63
ASP A  56
 None
 0.82A 2avdB-1bouA:
undetectable		 2avdB-1bouA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.82A 2f8gB-1bouB:
undetectable		 2f8gB-1bouB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B 136
ILE B   8
GLY B 189
 None
 0.87A 2hs1B-1bouB:
0.0		 2hs1B-1bouB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		5 / 12 PHE A  96
ALA B  15
ALA A 119
GLY B 203
TYR A  79
 None
 1.03A 2igtA-1bouA:
undetectable		 2igtA-1bouA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.88A 2o4kB-1bouB:
undetectable		 2o4kB-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.83A 2o4lB-1bouB:
undetectable		 2o4lB-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.75A 2q5kB-1bouB:
undetectable		 2q5kB-1bouB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 1.05A 2r5qA-1bouB:
undetectable		 2r5qA-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.83A 2r5qB-1bouB:
undetectable		 2r5qB-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 1.05A 2r5qC-1bouB:
undetectable		 2r5qC-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 HIS B 105
ALA B 107
GLY B  76
ILE B 148
VAL B 185
 None
 1.21A 2uxpB-1bouB:
0.0		 2uxpB-1bouB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU A  37
LEU A  61
ALA A  73
LEU A  75
PHE A  53
 None
 1.18A 2vcvE-1bouA:
0.0		 2vcvE-1bouA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU A  37
LEU A  61
ALA A  73
LEU A  75
PHE A  53
 None
 1.22A 2vcvH-1bouA:
undetectable		 2vcvH-1bouA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 ILE B 172
MET B 135
PHE B  34
ALA B  19
ALA B  15
 None
 1.21A 2x2nD-1bouB:
0.0		 2x2nD-1bouB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B  56
VAL B  57
ASP B 126
SER A  97
PHE A 103
 None
 1.11A 2y00A-1bouB:
undetectable		 2y00A-1bouB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B  56
VAL B  57
ASP B 126
SER A  97
PHE A 103
 None
 1.12A 2y00B-1bouB:
undetectable		 2y00B-1bouB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B  56
VAL B  57
ASP B 126
SER A  97
PHE A 103
 None
 1.12A 2y01B-1bouB:
undetectable		 2y01B-1bouB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		3 / 3 TYR A  90
GLU B 242
THR B 271
 None
FE  B 501 ( 2.4A)
None
 0.88A 2y7hB-1bouA:
undetectable		 2y7hB-1bouA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 191
ILE B 214
LEU B 217
LEU B 224
MET B 249
 FE  B 501 ( 4.8A)
None
None
None
None
 1.31A 3adsB-1bouB:
undetectable		 3adsB-1bouB:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		6 / 12 LEU B  16
GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 1.03A 3bvbA-1bouB:
undetectable		 3bvbA-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 1.13A 3d1yB-1bouB:
undetectable		 3d1yB-1bouB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 LEU B 102
ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.93A 3ebzA-1bouB:
0.0		 3ebzA-1bouB:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 10 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.94A 3em3B-1bouB:
undetectable		 3em3B-1bouB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.91A 3em4A-1bouB:
undetectable		 3em4A-1bouB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.93A 3em6B-1bouB:
undetectable		 3em6B-1bouB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		6 / 12 LEU B  16
GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 1.02A 3jw2B-1bouB:
undetectable		 3jw2B-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 10 ILE B 248
VAL B  57
ILE B  55
ILE B 172
SER B 171
 None
 1.40A 3kpbD-1bouB:
undetectable		 3kpbD-1bouB:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.91A 3nu3A-1bouB:
undetectable		 3nu3A-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		6 / 12 LEU B 133
ILE B 277
GLY B   7
VAL B 187
PRO B  51
ILE B 136
 None
 1.20A 3nu5A-1bouB:
0.0		 3nu5A-1bouB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 10 ILE B 277
GLY B   7
VAL B 187
PRO B  51
ILE B 136
 None
 1.09A 3oxvB-1bouB:
undetectable		 3oxvB-1bouB:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 ILE B 277
GLY B   7
VAL B 187
PRO B  51
ILE B 136
 None
 1.07A 3oxvD-1bouB:
undetectable		 3oxvD-1bouB:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 10 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.96A 3oxwB-1bouB:
undetectable		 3oxwB-1bouB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 LEU B 102
ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.85A 3s53B-1bouB:
undetectable		 3s53B-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B  16
GLY B 274
ILE B 136
GLY B 189
VAL B 131
 None
 1.00A 3ucbA-1bouB:
undetectable		 3ucbA-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 8 GLY B 192
GLY B 191
GLY B 128
LEU B  56
VAL B 131
 None
FE  B 501 ( 4.8A)
None
None
None
 1.33A 3v1nA-1bouB:
undetectable		 3v1nA-1bouB:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B 234
ARG A 133
ILE B 230
 None
 0.85A 4b7qC-1bouB:
undetectable		 4b7qC-1bouB:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.94A 4dqbA-1bouB:
undetectable		 4dqbA-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		5 / 12 ALA A 107
GLY A 108
GLY A 126
HIS B 195
GLU B 239
 None
 1.15A 4jlgA-1bouA:
undetectable		 4jlgA-1bouA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 11 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 0.96A 4njtA-1bouB:
undetectable		 4njtA-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.41A 4r88A-1bouB:
undetectable		 4r88A-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.39A 4r88B-1bouB:
undetectable		 4r88B-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.42A 4r88C-1bouB:
undetectable		 4r88C-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.43A 4r88D-1bouB:
undetectable		 4r88D-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.39A 4r88E-1bouB:
undetectable		 4r88E-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 HIS B  61
HIS B  12
GLU B  86
ASP B 126
SER B  63
 FE  B 501 ( 3.3A)
FE  B 501 ( 3.3A)
None
None
None
 1.43A 4r88F-1bouB:
undetectable		 4r88F-1bouB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 6 PHE B  81
LYS B  97
GLY B  98
ALA B 103
 None
 1.30A 4yshB-1bouB:
0.0		 4yshB-1bouB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 162
LEU B 168
VAL B 244
TRP B 246
VAL B 152
 None
 1.08A 5dpdB-1bouB:
undetectable		 5dpdB-1bouB:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 102
ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.81A 5e5jA-1bouB:
undetectable		 5e5jA-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 102
ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.88A 5e5jB-1bouB:
undetectable		 5e5jB-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 LEU B 102
ALA B 175
GLY B 169
ILE B 148
ILE B 106
 None
 0.81A 5e5kB-1bouB:
undetectable		 5e5kB-1bouB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		3 / 3 ARG B  91
VAL B  96
TRP B 143
 None
 0.90A 5fvoA-1bouB:
0.0		 5fvoA-1bouB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		3 / 3 TYR A 118
TYR B 264
SER B 194
 None
 1.00A 5iktB-1bouA:
undetectable		 5iktB-1bouA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
(Sphingomonas
paucimobilis) 		5 / 8 ARG A  77
LEU A  92
LEU A  95
LEU A  66
LEU A  37
 None
 1.41A 5jqbA-1bouA:
undetectable
5jqbB-1bouA:
undetectable		 5jqbA-1bouA:
18.18
5jqbB-1bouA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 1.05A 5kqxB-1bouB:
undetectable		 5kqxB-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B  16
GLY B 274
ALA B 275
GLY B 189
VAL B 131
 None
 1.02A 5kr0B-1bouB:
undetectable		 5kr0B-1bouB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 9 LEU B 133
ILE B 277
GLY B   7
PRO B  51
ILE B 136
 None
 1.00A 5kr2D-1bouB:
undetectable		 5kr2D-1bouB:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		5 / 12 VAL B 155
GLU B  86
PHE A  96
THR A  98
GLY B  87
 None
 1.33A 5xioA-1bouB:
undetectable		 5xioA-1bouB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 5 VAL B 187
TRP B 188
PRO B  51
THR B 190
 None
 1.34A 6cduA-1bouB:
0.0
6cduB-1bouB:
undetectable		 6cduA-1bouB:
21.15
6cduB-1bouB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 5 VAL B 187
TRP B 188
PRO B  51
THR B 190
 None
 1.22A 6cduI-1bouB:
0.0
6cduJ-1bouB:
0.0		 6cduI-1bouB:
21.15
6cduJ-1bouB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.83A 6difB-1bouB:
undetectable		 6difB-1bouB:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.83A 6dj1B-1bouB:
undetectable		 6dj1B-1bouB:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 GLY B 274
ALA B 275
ILE B   8
GLY B 189
VAL B 131
 None
 0.85A 6dj2B-1bouB:
undetectable		 6dj2B-1bouB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		5 / 12 ILE B 106
PHE B 115
GLY B 169
ALA B 252
ASP B 170
 None
 1.11A 6dwnD-1bouB:
0.0		 6dwnD-1bouB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1bou 4,5-DIOXYGENASE BETA
CHAIN
(Sphingomonas
paucimobilis) 		4 / 7 TRP B  43
THR B   6
ARG B 291
ASP B 259
 None
 1.30A 6mn4E-1bouB:
0.0		 6mn4E-1bouB:
21.04