SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		8 / 12 PRO A  25
ILE A  63
TYR A  68
PHE A 105
TYR A 110
GLU A 134
ILE A 136
TYR A 149
 None
 0.84A 3q5pA-1bowA:
21.3		 3q5pA-1bowA:
61.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		5 / 12 PRO A  25
VAL A  28
TYR A  68
GLU A 134
ILE A 136
 None
 1.36A 3q5pA-1bowA:
21.3		 3q5pA-1bowA:
61.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		7 / 11 PRO A  25
ILE A  63
TYR A  68
PHE A 105
TYR A 110
GLU A 134
ILE A 136
 None
 0.79A 3q5rA-1bowA:
20.9		 3q5rA-1bowA:
66.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		5 / 11 PRO A  25
VAL A  28
TYR A  68
GLU A 134
ILE A 136
 None
 1.27A 3q5rA-1bowA:
20.9		 3q5rA-1bowA:
66.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		4 / 6 VAL A  28
TYR A  68
GLU A 134
ILE A 136
 None
 1.19A 3q5sA-1bowA:
21.3		 3q5sA-1bowA:
66.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		4 / 5 GLU A  26
GLY A  24
TYR A 110
GLU A 134
 None
 1.49A 3w9tC-1bowA:
0.0		 3w9tC-1bowA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		4 / 5 GLU A  26
GLY A  24
TYR A 110
GLU A 134
 None
 1.49A 3w9tD-1bowA:
0.0		 3w9tD-1bowA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		4 / 5 GLU A  26
GLY A  24
TYR A 110
GLU A 134
 None
 1.49A 3w9tG-1bowA:
0.0		 3w9tG-1bowA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR
(Bacillus
subtilis) 		4 / 6 ASP A 131
THR A  54
TYR A  68
THR A  67
 None
 1.25A 5b6iB-1bowA:
undetectable		 5b6iB-1bowA:
18.03