SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		5 / 9 LEU A 325
LEU A  15
ILE A  38
VAL A 305
PHE A 304
 None
 1.34A 1gx8A-1bpoA:
0.0		 1gx8A-1bpoA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		3 / 3 LEU A 466
LEU A 463
SER A 460
 None
 0.66A 1tlmA-1bpoA:
0.1		 1tlmA-1bpoA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		5 / 11 THR A 312
ALA A 307
GLN A 265
ILE A 316
THR A 158
 None
 1.43A 3qelA-1bpoA:
undetectable
3qelB-1bpoA:
undetectable		 3qelA-1bpoA:
21.60
3qelB-1bpoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 7 ILE A  40
THR A  29
PHE A 304
ASP A  35
 None
 0.99A 4iarA-1bpoA:
undetectable		 4iarA-1bpoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 5 LYS A 453
LEU A 452
GLU A 449
LEU A 448
 None
 1.27A 4k4yA-1bpoA:
0.0		 4k4yA-1bpoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 4 LYS A 453
LEU A 452
GLU A 449
LEU A 448
 None
 1.29A 4k4yE-1bpoA:
0.0		 4k4yE-1bpoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 5 LYS A 453
LEU A 452
GLU A 449
LEU A 448
 None
 1.24A 4k4yI-1bpoA:
0.0		 4k4yI-1bpoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 6 ILE A  38
PHE A  37
ILE A  20
LEU A  13
 None
 0.78A 4o8fB-1bpoA:
undetectable		 4o8fB-1bpoA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		3 / 3 GLU A 133
TRP A 130
ASN A  74
 None
 1.11A 5dv4A-1bpoA:
undetectable		 5dv4A-1bpoA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 8 LEU A 148
ILE A 170
GLY A 196
LEU A 166
 None
 0.77A 5eseA-1bpoA:
0.0		 5eseA-1bpoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		5 / 12 THR A 312
ALA A 307
GLN A 265
ILE A 316
THR A 158
 None
 1.34A 5ewjC-1bpoA:
undetectable
5ewjD-1bpoA:
undetectable		 5ewjC-1bpoA:
21.75
5ewjD-1bpoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		5 / 11 ILE A  52
ILE A  40
THR A  31
VAL A  79
LEU A  82
 None
 1.46A 5jkwA-1bpoA:
0.0		 5jkwA-1bpoA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 6 ASP A 423
LEU A 422
GLY A 419
PHE A 418
 None
 1.05A 5nooC-1bpoA:
undetectable		 5nooC-1bpoA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		5 / 12 PHE A  37
ILE A  52
SER A  97
VAL A  79
ILE A  80
 None
 1.38A 6gsdA-1bpoA:
undetectable		 6gsdA-1bpoA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bpo PROTEIN (CLATHRIN)
(Rattus
norvegicus) 		4 / 6 GLN A 265
PHE A 274
LEU A 287
PHE A 204
 None
 1.25A 6nmpC-1bpoA:
undetectable
6nmpJ-1bpoA:
0.0		 6nmpC-1bpoA:
18.51
6nmpJ-1bpoA:
8.33