SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 GLY A 215
GLY A 214
VAL A 226
LEU A 240
LEU A 212
 None
 1.04A 1mx1F-1bqgA:
undetectable		 1mx1F-1bqgA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 9 LEU A 388
ILE A 390
THR A 373
THR A 358
ALA A 355
 None
 1.19A 2m9qA-1bqgA:
0.0		 2m9qA-1bqgA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 10 ILE A 352
PHE A 350
GLY A 380
PHE A 181
ARG A  44
 None
 1.47A 2piwA-1bqgA:
undetectable		 2piwA-1bqgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 LEU A 129
LEU A 126
GLN A 326
ARG A  94
LEU A  47
 None
 1.45A 2w8yB-1bqgA:
undetectable		 2w8yB-1bqgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 ASN A 185
PHE A  42
GLY A  39
TYR A 170
PHE A 350
 None
 1.46A 3a27A-1bqgA:
0.8		 3a27A-1bqgA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 11 ILE A 376
ARG A 184
PHE A 207
VAL A 151
LEU A 394
 None
 1.01A 3a9eB-1bqgA:
0.0		 3a9eB-1bqgA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 6 GLY A  57
GLN A 132
ILE A  48
VAL A  58
 None
 1.13A 3kvvC-1bqgA:
undetectable		 3kvvC-1bqgA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 6 ALA A 118
ILE A  67
VAL A  21
ASN A  45
 None
 1.18A 3nneG-1bqgA:
undetectable		 3nneG-1bqgA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 5 HIS A 416
LEU A  71
LEU A  19
ASP A  73
 None
 1.31A 4aqlA-1bqgA:
3.8		 4aqlA-1bqgA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 8 GLY A  57
VAL A  56
HIS A  55
GLN A 132
 None
 0.83A 4fglD-1bqgA:
0.4		 4fglD-1bqgA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 8 HIS A 321
PRO A 320
ASP A 319
SER A 344
 None
 1.04A 4l7iB-1bqgA:
undetectable		 4l7iB-1bqgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 LEU A 262
VAL A 226
LEU A 217
ILE A 223
ALA A 251
 None
 1.06A 4ltwA-1bqgA:
undetectable		 4ltwA-1bqgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 6 LEU A 212
LEU A 197
VAL A 194
PHE A 158
 None
 1.10A 4uswA-1bqgA:
0.0		 4uswA-1bqgA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		6 / 9 ALA A 121
LEU A  71
ALA A 118
LEU A  78
LEU A  49
ALA A 125
 None
 1.20A 4z91F-1bqgA:
0.0
4z91G-1bqgA:
0.0
4z91H-1bqgA:
0.0
4z91I-1bqgA:
0.7
4z91J-1bqgA:
0.0		 4z91F-1bqgA:
22.05
4z91G-1bqgA:
22.05
4z91H-1bqgA:
22.05
4z91I-1bqgA:
22.05
4z91J-1bqgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		6 / 9 LEU A  47
ALA A 121
LEU A  71
LEU A  78
LEU A  49
ALA A 125
 None
 1.02A 4z91F-1bqgA:
0.0
4z91G-1bqgA:
0.0
4z91H-1bqgA:
0.0
4z91I-1bqgA:
0.7
4z91J-1bqgA:
0.0		 4z91F-1bqgA:
22.05
4z91G-1bqgA:
22.05
4z91H-1bqgA:
22.05
4z91I-1bqgA:
22.05
4z91J-1bqgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		6 / 9 LEU A  49
ALA A 125
ALA A 121
LEU A  71
ALA A 118
LEU A  78
 None
 1.25A 4z91F-1bqgA:
0.0
4z91G-1bqgA:
0.0
4z91H-1bqgA:
0.0
4z91I-1bqgA:
0.7
4z91J-1bqgA:
0.0		 4z91F-1bqgA:
22.05
4z91G-1bqgA:
22.05
4z91H-1bqgA:
22.05
4z91I-1bqgA:
22.05
4z91J-1bqgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		6 / 9 LEU A  49
ALA A 125
LEU A  47
ALA A 121
LEU A  71
LEU A  78
 None
 1.03A 4z91F-1bqgA:
0.0
4z91G-1bqgA:
0.0
4z91H-1bqgA:
0.0
4z91I-1bqgA:
0.7
4z91J-1bqgA:
0.0		 4z91F-1bqgA:
22.05
4z91G-1bqgA:
22.05
4z91H-1bqgA:
22.05
4z91I-1bqgA:
22.05
4z91J-1bqgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		6 / 9 LEU A  78
LEU A  49
ALA A 125
LEU A  47
ALA A 121
LEU A  71
 None
 0.99A 4z91F-1bqgA:
0.0
4z91G-1bqgA:
0.0
4z91H-1bqgA:
0.0
4z91I-1bqgA:
0.7
4z91J-1bqgA:
0.0		 4z91F-1bqgA:
22.05
4z91G-1bqgA:
22.05
4z91H-1bqgA:
22.05
4z91I-1bqgA:
22.05
4z91J-1bqgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.68A 5bs8A-1bqgA:
0.0
5bs8C-1bqgA:
0.0
5bs8D-1bqgA:
0.9		 5bs8A-1bqgA:
23.27
5bs8C-1bqgA:
23.27
5bs8D-1bqgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.67A 5bs8A-1bqgA:
0.0
5bs8B-1bqgA:
0.9
5bs8C-1bqgA:
0.0		 5bs8A-1bqgA:
23.27
5bs8B-1bqgA:
21.19
5bs8C-1bqgA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.73A 5btdA-1bqgA:
0.0
5btdB-1bqgA:
0.9
5btdC-1bqgA:
0.0		 5btdA-1bqgA:
23.27
5btdB-1bqgA:
21.19
5btdC-1bqgA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.74A 5btdA-1bqgA:
0.0
5btdC-1bqgA:
0.0
5btdD-1bqgA:
undetectable		 5btdA-1bqgA:
23.27
5btdC-1bqgA:
23.27
5btdD-1bqgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 6 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.72A 5btgA-1bqgA:
0.0
5btgB-1bqgA:
0.9
5btgC-1bqgA:
0.0		 5btgA-1bqgA:
23.27
5btgB-1bqgA:
21.19
5btgC-1bqgA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 ALA A  96
ARG A  68
GLY A  66
GLU A  65
 None
 0.76A 5btgA-1bqgA:
0.0
5btgC-1bqgA:
0.0
5btgD-1bqgA:
undetectable		 5btgA-1bqgA:
23.27
5btgC-1bqgA:
23.27
5btgD-1bqgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 LEU A 388
THR A 358
PRO A 398
MET A 325
 None
 1.06A 5fxtA-1bqgA:
undetectable		 5fxtA-1bqgA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		3 / 3 TRP A 246
GLU A 222
ASP A 241
 None
 0.62A 5gqbA-1bqgA:
5.7		 5gqbA-1bqgA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 4 ASN A 295
LEU A 317
SER A 346
LEU A 154
 None
 1.38A 5kb5A-1bqgA:
0.4		 5kb5A-1bqgA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 ILE A 223
LEU A 254
PRO A 242
VAL A 226
GLY A 214
 None
 1.16A 5nnaA-1bqgA:
0.0		 5nnaA-1bqgA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 12 ILE A 223
LEU A 254
PRO A 242
VAL A 226
GLY A 214
 None
 1.12A 5nnaC-1bqgA:
0.0		 5nnaC-1bqgA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 7 HIS A  38
ASP A 241
GLY A 214
ASN A  33
 None
 0.94A 5x7pA-1bqgA:
undetectable		 5x7pA-1bqgA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		4 / 5 HIS A  38
ASP A 241
GLY A 214
ASN A  33
 None
 0.91A 5x7pB-1bqgA:
0.0		 5x7pB-1bqgA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		5 / 10 PHE A 350
GLY A 380
ARG A 382
ALA A 411
LEU A 383
 None
 1.24A 5zjiA-1bqgA:
undetectable
5zjiJ-1bqgA:
undetectable		 5zjiA-1bqgA:
11.37
5zjiJ-1bqgA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1bqg D-GLUCARATE
DEHYDRATASE
(Pseudomonas
putida) 		3 / 3 LEU A 130
ASN A  91
LEU A  78
 None
 0.70A 6exiA-1bqgA:
undetectable		 6exiA-1bqgA:
11.87