SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
6 / 8 HIS A  57
ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
0GJ  A   1 ( 2.7A)
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.64A 1aq7A-1bqyA:
34.7
1aq7A-1bqyA:
42.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 ALA A  55
VAL A  99
TRP A 215
None
0GJ  A   1 ( 4.2A)
None
0.83A 1av2A-1bqyA:
undetectable
1av2B-1bqyA:
undetectable
1av2A-1bqyA:
7.01
1av2B-1bqyA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 TRP A 215
ALA A  55
VAL A  99
None
None
0GJ  A   1 ( 4.2A)
0.77A 1av2C-1bqyA:
undetectable
1av2D-1bqyA:
undetectable
1av2C-1bqyA:
7.01
1av2D-1bqyA:
7.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
6 / 9 ASP A 189
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.33A 1bcuH-1bqyA:
17.3
1bcuH-1bqyA:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 9 HIS A  57
ASP A 189
SER A 195
TRP A 215
GLY A 226
0GJ  A   1 ( 2.7A)
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 ( 4.3A)
0.35A 1dwcH-1bqyA:
32.2
1dwcH-1bqyA:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
7 / 12 HIS A  57
ASP A 189
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
0GJ  A   1 ( 2.7A)
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.61A 1etrH-1bqyA:
32.2
1etrH-1bqyA:
32.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 8 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.44A 1f5lA-1bqyA:
32.6
1f5lA-1bqyA:
32.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 9 GLY A 184
GLU A 224
GLY A 223
GLY A 216
GLY A 217
None
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 (-4.1A)
1.07A 1mxdA-1bqyA:
0.0
1mxdA-1bqyA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 11 GLY A 184
GLU A 224
GLY A 223
GLY A 216
GLY A 217
None
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 (-4.1A)
1.03A 1mxgA-1bqyA:
undetectable
1mxgA-1bqyA:
20.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 6 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.40A 1tnlA-1bqyA:
35.5
1tnlA-1bqyA:
42.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 ALA A  55
VAL A  99
TRP A 215
None
0GJ  A   1 ( 4.2A)
None
0.80A 1w5uA-1bqyA:
undetectable
1w5uB-1bqyA:
undetectable
1w5uA-1bqyA:
7.01
1w5uB-1bqyA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 TRP A 215
ALA A  55
VAL A  99
None
None
0GJ  A   1 ( 4.2A)
0.76A 1w5uA-1bqyA:
undetectable
1w5uB-1bqyA:
undetectable
1w5uA-1bqyA:
7.01
1w5uB-1bqyA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 ALA A  55
VAL A  99
TRP A 215
None
0GJ  A   1 ( 4.2A)
None
0.76A 2izqA-1bqyA:
undetectable
2izqB-1bqyA:
undetectable
2izqA-1bqyA:
7.01
2izqB-1bqyA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 TRP A 215
ALA A  55
VAL A  99
None
None
0GJ  A   1 ( 4.2A)
0.87A 2izqC-1bqyA:
undetectable
2izqD-1bqyA:
undetectable
2izqC-1bqyA:
7.01
2izqD-1bqyA:
7.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 6 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.29A 2otvA-1bqyA:
35.8
2otvA-1bqyA:
42.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
7 / 12 ASP A 189
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
TYR A 228
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
None
0.37A 2p16A-1bqyA:
13.0
2p16A-1bqyA:
28.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 8 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.48A 2vinA-1bqyA:
10.1
2vinA-1bqyA:
32.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
7 / 12 ASP A 189
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 217
TYR A 228
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 (-4.1A)
None
0.86A 2w26A-1bqyA:
11.8
2w26A-1bqyA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
7 / 12 ASP A 189
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
TYR A 228
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
None
0.33A 2w26A-1bqyA:
11.8
2w26A-1bqyA:
28.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
6 / 11 HIS A  57
ASP A 189
SER A 195
TRP A 215
GLY A 216
GLY A 226
0GJ  A   1 ( 2.7A)
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.48A 3gy3A-1bqyA:
34.1
3gy3A-1bqyA:
42.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 TRP A 215
ALA A  55
VAL A  99
None
None
0GJ  A   1 ( 4.2A)
1.01A 3l8lA-1bqyA:
undetectable
3l8lB-1bqyA:
undetectable
3l8lA-1bqyA:
7.01
3l8lB-1bqyA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 TRP A 215
ALA A  55
VAL A  99
None
None
0GJ  A   1 ( 4.2A)
0.87A 3l8lC-1bqyA:
undetectable
3l8lD-1bqyA:
undetectable
3l8lC-1bqyA:
7.01
3l8lD-1bqyA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
3 / 3 VAL A 227
VAL A 213
TRP A 215
None
0.96A 3l8lC-1bqyA:
undetectable
3l8lD-1bqyA:
undetectable
3l8lC-1bqyA:
7.01
3l8lD-1bqyA:
8.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 6 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.30A 3rxfA-1bqyA:
15.3
3rxfA-1bqyA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
4 / 5 ASP A 189
SER A 195
VAL A 213
GLY A 226
0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 ( 4.3A)
0.41A 3rxhA-1bqyA:
35.4
3rxhA-1bqyA:
42.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 9 ALA A 183
ILE A 138
VAL A 213
GLY A 216
ILE A 160
None
None
None
0GJ  A   1 (-3.5A)
None
0.99A 3s43A-1bqyA:
undetectable
3s43A-1bqyA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
4 / 7 SER A 195
THR A 229
THR A 180
TYR A 234
0GJ  A   1 ( 1.4A)
None
None
None
0.80A 3tneB-1bqyA:
undetectable
3tneB-1bqyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 12 LEU A 105
ILE A 212
ILE A 242
PHE A 209
LEU A 123
None
1.40A 3vw1B-1bqyA:
undetectable
3vw1B-1bqyA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
4 / 8 GLY A  44
VAL A  31
PHE A 209
ILE A  47
None
0.68A 4fglD-1bqyA:
undetectable
4fglD-1bqyA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
4 / 7 GLY A  44
VAL A  31
PHE A 209
ILE A  47
None
0.66A 4fglC-1bqyA:
undetectable
4fglC-1bqyA:
17.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 12 HIS A  57
ASP A 189
VAL A 213
TRP A 215
GLY A 226
0GJ  A   1 ( 2.7A)
0GJ  A   1 (-3.1A)
None
None
0GJ  A   1 ( 4.3A)
0.26A 4hfpD-1bqyA:
31.9
4hfpD-1bqyA:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri)
5 / 12 HIS A  57
VAL A 213
TRP A 215
GLY A 216
GLY A 226
0GJ  A   1 ( 2.7A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
0.38A 4rn6B-1bqyA:
27.4
4rn6B-1bqyA:
29.73