SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1br2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))
1br2 MYOSIN
(Gallus
gallus)
4 / 7 VAL A 387
LEU A 613
VAL A 621
LEU A 362
None
0.79A 1cqpA-1br2A:
undetectable
1cqpB-1br2A:
undetectable
1cqpA-1br2A:
12.85
1cqpB-1br2A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.07A 1n6cA-1br2A:
undetectable
1n6cA-1br2A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 6 TYR A 484
HIS A 585
PRO A 531
VAL A 537
None
1.36A 1q13A-1br2A:
undetectable
1q13A-1br2A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 THR A 335
PHE A 332
LEU A 438
VAL A 355
PHE A 620
None
1.37A 1q23L-1br2A:
0.0
1q23L-1br2A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 402
ALA A 423
ILE A 278
MET A 391
PHE A 398
None
1.23A 1xzxX-1br2A:
0.0
1xzxX-1br2A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 402
ALA A 423
ILE A 278
MET A 391
PHE A 398
None
1.20A 1y0xX-1br2A:
undetectable
1y0xX-1br2A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 PHE A 332
ALA A 233
GLY A 235
THR A 335
LEU A 624
None
1.02A 2hw2A-1br2A:
0.0
2hw2A-1br2A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 LEU A 670
SER A 179
TYR A 586
ASN A 483
ALA A 467
None
ALF  A 999 (-2.7A)
None
None
None
1.45A 2vdmA-1br2A:
0.0
2vdmB-1br2A:
undetectable
2vdmA-1br2A:
19.49
2vdmB-1br2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 8 LEU A 362
PHE A 367
MET A 378
PHE A 398
None
0.98A 2weyB-1br2A:
undetectable
2weyB-1br2A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 PRO A 604
LEU A 605
ILE A 402
VAL A 387
LEU A 362
None
1.35A 3a51B-1br2A:
1.8
3a51B-1br2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
1br2 MYOSIN
(Gallus
gallus)
4 / 8 GLY A 588
GLU A 487
ASN A 483
ILE A 471
None
0.96A 3aodA-1br2A:
1.4
3aodA-1br2A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 TYR A 127
TYR A 108
ILE A 124
ADP  A 998 (-4.4A)
None
None
0.80A 3eteA-1br2A:
0.0
3eteB-1br2A:
0.0
3eteA-1br2A:
20.75
3eteB-1br2A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)
1br2 MYOSIN
(Gallus
gallus)
4 / 8 LEU A 316
GLN A 280
TYR A 291
PHE A 290
None
1.35A 3po7A-1br2A:
undetectable
3po7A-1br2A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 7 LEU A 705
GLN A 490
PHE A 493
LEU A 519
None
0.98A 3qeoB-1br2A:
1.6
3qeoB-1br2A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 GLY A 180
GLY A 182
THR A 184
ADP  A 998 (-3.8A)
ADP  A 998 (-3.3A)
MG  A 997 ( 3.0A)
0.44A 3si7B-1br2A:
0.0
3si7B-1br2A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)
1br2 MYOSIN
(Gallus
gallus)
4 / 7 ASN A 606
PHE A 367
MET A 378
PHE A 398
None
1.28A 3tvxB-1br2A:
undetectable
3tvxB-1br2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)
1br2 MYOSIN
(Gallus
gallus)
4 / 5 LEU A 307
GLY A 309
PHE A 290
ASN A 364
None
1.32A 3uq6B-1br2A:
undetectable
3uq6B-1br2A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)
1br2 MYOSIN
(Gallus
gallus)
4 / 6 GLU A 185
ASP A 465
ASP A 243
ASN A 236
ADP  A 998 (-4.7A)
MG  A 997 ( 3.3A)
None
None
1.13A 3vywA-1br2A:
undetectable
3vywA-1br2A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)
1br2 MYOSIN
(Gallus
gallus)
4 / 5 GLU A 185
ASP A 465
ASP A 243
ASN A 236
ADP  A 998 (-4.7A)
MG  A 997 ( 3.3A)
None
None
1.14A 3vywD-1br2A:
undetectable
3vywD-1br2A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)
1br2 MYOSIN
(Gallus
gallus)
4 / 5 GLU A 178
GLY A 177
TYR A 586
GLN A 490
None
1.35A 3w9tE-1br2A:
0.0
3w9tE-1br2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)
1br2 MYOSIN
(Gallus
gallus)
4 / 5 GLU A 178
GLY A 177
TYR A 586
GLN A 490
None
1.37A 3w9tG-1br2A:
undetectable
3w9tG-1br2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.11A 4e47A-1br2A:
undetectable
4e47A-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.14A 4e47B-1br2A:
undetectable
4e47B-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.09A 4e47C-1br2A:
undetectable
4e47C-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 ASP A 618
ARG A 354
ASP A 623
None
0.86A 4fp9A-1br2A:
undetectable
4fp9A-1br2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 ASP A 618
ARG A 354
ASP A 623
None
0.89A 4fp9C-1br2A:
undetectable
4fp9C-1br2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 ASP A 618
ARG A 354
ASP A 623
None
0.81A 4fp9F-1br2A:
undetectable
4fp9F-1br2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 PRO A 687
TYR A 127
GLY A 694
None
ADP  A 998 (-4.4A)
None
0.71A 4g2zA-1br2A:
undetectable
4g2zA-1br2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.16A 4jdsA-1br2A:
undetectable
4jdsA-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.14A 4jdsB-1br2A:
undetectable
4jdsB-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.13A 4jdsC-1br2A:
undetectable
4jdsC-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.09A 4jlgA-1br2A:
0.0
4jlgA-1br2A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 7 VAL A 123
ILE A 153
ILE A 156
ALA A 155
None
0.88A 4lv9A-1br2A:
undetectable
4lv9A-1br2A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 7 VAL A 123
ILE A 153
ILE A 156
ALA A 155
None
0.90A 4lv9B-1br2A:
undetectable
4lv9B-1br2A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)
1br2 MYOSIN
(Gallus
gallus)
6 / 12 LEU A 225
LEU A 450
ALA A 227
ILE A 254
ALA A 265
ILE A 463
None
1.31A 4o2bD-1br2A:
undetectable
4o2bD-1br2A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1br2 MYOSIN
(Gallus
gallus)
6 / 12 ILE A 725
LEU A 784
ALA A 782
PHE A 776
ILE A 757
ILE A 774
None
1.41A 4pssA-1br2A:
undetectable
4pssA-1br2A:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)
1br2 MYOSIN
(Gallus
gallus)
5 / 10 PHE A 234
ALA A 233
VAL A 356
LEU A 305
PHE A 332
None
1.31A 4zmeB-1br2A:
0.0
4zmeB-1br2A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
1br2 MYOSIN
(Gallus
gallus)
5 / 11 ILE A 686
ALA A 181
GLY A 182
GLU A 185
ASN A 236
None
ADP  A 998 ( 4.5A)
ADP  A 998 (-3.3A)
ADP  A 998 (-4.7A)
None
1.04A 5ayfA-1br2A:
undetectable
5ayfA-1br2A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1br2 MYOSIN
(Gallus
gallus)
4 / 5 ALA A 693
TYR A 127
PRO A 324
GLY A 319
None
ADP  A 998 (-4.4A)
None
None
0.95A 5eslA-1br2A:
0.0
5eslA-1br2A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 PHE A 472
TYR A 586
ILE A 466
GLY A 468
ILE A 482
None
None
None
ALF  A 999 (-2.8A)
None
1.12A 5ifuA-1br2A:
undetectable
5ifuA-1br2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 GLU A 504
HIS A 495
LEU A 492
THR A 672
ARG A 507
None
1.11A 5m5cB-1br2A:
undetectable
5m5cB-1br2A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.17A 5n0oA-1br2A:
1.7
5n0oA-1br2A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.17A 5n0rA-1br2A:
0.5
5n0rA-1br2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.18A 5n0wA-1br2A:
0.6
5n0wA-1br2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.16A 5n0xB-1br2A:
0.5
5n0xB-1br2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 ARG A 107
PHE A  44
LEU A 696
None
0.87A 5veuA-1br2A:
0.4
5veuA-1br2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)
1br2 MYOSIN
(Gallus
gallus)
5 / 12 GLN A 129
LEU A 130
PRO A 131
ILE A 113
VAL A 123
ADP  A 998 ( 4.4A)
None
None
None
None
1.13A 6debB-1br2A:
undetectable
6debB-1br2A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
1br2 MYOSIN
(Gallus
gallus)
3 / 3 GLN A 361
TYR A 313
ASN A 364
None
0.86A 6dwdC-1br2A:
0.0
6dwdC-1br2A:
21.99