SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1brt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		8 / 10 GLY A  31
PHE A  32
LEU A 125
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
 None
None
None
None
CL  A 278 (-4.6A)
None
None
None
 0.62A 1a8uA-1brtA:
50.3		 1a8uA-1brtA:
98.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		8 / 10 GLY A  31
PHE A  32
SER A  98
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
 None
None
None
None
CL  A 278 (-4.6A)
None
None
None
 0.63A 1a8uA-1brtA:
50.3		 1a8uA-1brtA:
98.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		8 / 10 GLY A  31
PHE A  32
LEU A 125
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
 None
None
None
None
CL  A 278 (-4.6A)
None
None
None
 0.66A 1a8uB-1brtA:
49.9		 1a8uB-1brtA:
98.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		8 / 10 GLY A  31
PHE A  32
SER A  98
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
 None
None
None
None
CL  A 278 (-4.6A)
None
None
None
 0.65A 1a8uB-1brtA:
49.9		 1a8uB-1brtA:
98.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 THR A 236
ASP A 228
HIS A 257
HIS A 224
 None
 1.03A 1ei6A-1brtA:
undetectable		 1ei6A-1brtA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 8 ILE A 148
PHE A 144
ARG A 229
LEU A 231
 None
 0.89A 1v55N-1brtA:
0.0
1v55W-1brtA:
0.0		 1v55N-1brtA:
20.34
1v55W-1brtA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 8 ILE A 148
PHE A 144
ARG A 229
LEU A 231
 None
 0.90A 2einA-1brtA:
0.0
2einJ-1brtA:
0.0		 2einA-1brtA:
20.34
2einJ-1brtA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 6 ALA A 198
ALA A 201
THR A 204
PHE A  76
 None
CL  A 278 (-3.7A)
None
None
 0.86A 2xfhA-1brtA:
0.0		 2xfhA-1brtA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 8 ILE A 148
PHE A 144
ARG A 229
LEU A 231
 None
 0.91A 3asoN-1brtA:
0.0
3asoW-1brtA:
0.0		 3asoN-1brtA:
20.34
3asoW-1brtA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		5 / 12 PHE A 121
TYR A  56
GLY A 102
GLY A 100
SER A 124
 None
 1.29A 3dlcA-1brtA:
1.9		 3dlcA-1brtA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 7 PHE A  61
ASP A  57
PRO A  67
ILE A  29
 None
 0.95A 4pcuA-1brtA:
3.4		 4pcuA-1brtA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
 None
 1.12A 4w5oA-1brtA:
4.2		 4w5oA-1brtA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 7 PHE A 121
SER A 124
ALA A 243
LEU A 244
 None
 1.10A 4xk8A-1brtA:
undetectable		 4xk8A-1brtA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
 None
 1.14A 4z4cA-1brtA:
4.0		 4z4cA-1brtA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
 None
 1.13A 4z4dA-1brtA:
4.0		 4z4dA-1brtA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
 None
 1.13A 4z4eA-1brtA:
undetectable		 4z4eA-1brtA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 7 ILE A 148
PHE A 144
ARG A 229
LEU A 231
 None
 0.91A 5b1bN-1brtA:
0.0
5b1bW-1brtA:
0.0		 5b1bN-1brtA:
20.34
5b1bW-1brtA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 7 ILE A 148
PHE A 144
ARG A 229
LEU A 231
 None
 0.93A 5b3sN-1brtA:
0.0
5b3sW-1brtA:
0.0		 5b3sN-1brtA:
20.34
5b3sW-1brtA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 7 LEU A 221
THR A 226
ASP A 228
LEU A 271
 None
 0.93A 5jq7B-1brtA:
undetectable		 5jq7B-1brtA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		5 / 12 SER A  38
HIS A  37
PHE A  61
GLY A  62
GLY A 193
 None
 0.88A 5l6eA-1brtA:
1.5		 5l6eA-1brtA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 ALA A 220
VAL A 218
PHE A 121
ILE A 116
 None
 1.01A 5of1B-1brtA:
undetectable		 5of1B-1brtA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 6 PRO A 219
VAL A 119
ALA A 247
PHE A 274
 None
 1.14A 5t7bA-1brtA:
4.5		 5t7bA-1brtA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 8 PHE A 164
SER A  38
HIS A  30
PHE A 167
 None
 1.04A 5y2tB-1brtA:
0.0		 5y2tB-1brtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		5 / 12 GLY A 254
PHE A 159
PHE A 163
THR A  99
LEU A 231
 None
None
None
CL  A 278 (-3.5A)
None
 1.14A 6e8qA-1brtA:
undetectable		 6e8qA-1brtA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		5 / 12 VAL A 104
LEU A  46
ALA A 120
PHE A 274
LEU A 275
 None
 1.19A 6ew0G-1brtA:
4.1		 6ew0G-1brtA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		6 / 10 VAL A  95
LEU A 122
LEU A 260
LEU A  46
THR A  55
LEU A 271
 None
 1.14A 6f5uA-1brtA:
0.1
6f5uB-1brtA:
undetectable		 6f5uA-1brtA:
15.33
6f5uB-1brtA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 1brt BROMOPEROXIDASE A2
(Kitasatospora
aureofaciens) 		4 / 5 GLN A  24
THR A  55
HIS A  20
LEU A  47
 None
 1.40A 6gbnA-1brtA:
6.3		 6gbnA-1brtA:
21.65