SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bs9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 10 VAL A 202
MET A 131
ILE A 129
TYR A 170
GLY A 195
 None
 1.09A 1pn0A-1bs9A:
2.8		 1pn0A-1bs9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 10 VAL A 202
MET A 131
ILE A 129
TYR A 170
GLY A 195
 None
 1.07A 1pn0B-1bs9A:
2.6		 1pn0B-1bs9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 10 VAL A 202
MET A 131
ILE A 129
TYR A 170
GLY A 195
 None
 1.06A 1pn0C-1bs9A:
0.0		 1pn0C-1bs9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 10 VAL A 202
MET A 131
ILE A 129
TYR A 170
GLY A 195
 None
 1.05A 1pn0D-1bs9A:
0.0		 1pn0D-1bs9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 12 GLN A 188
GLY A  92
HIS A 187
VAL A  68
ALA A  45
 None
 1.02A 1vptA-1bs9A:
undetectable		 1vptA-1bs9A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 11 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.13A 2q6hA-1bs9A:
undetectable		 2q6hA-1bs9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 12 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.14A 2qb4A-1bs9A:
undetectable		 2qb4A-1bs9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 11 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.14A 2qeiA-1bs9A:
undetectable		 2qeiA-1bs9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 11 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
 None
 1.15A 2qjuA-1bs9A:
undetectable		 2qjuA-1bs9A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 7 VAL A  26
GLY A   9
ALA A  40
SER A  22
 None
 0.88A 2wekB-1bs9A:
undetectable		 2wekB-1bs9A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		3 / 3 THR A 186
SER A 174
PHE A 136
 SO4  A 208 ( 4.2A)
SO4  A 208 (-2.5A)
None
 0.88A 3d4sA-1bs9A:
undetectable		 3d4sA-1bs9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		3 / 3 TYR A  43
TYR A  57
GLY A  92
 None
 0.61A 3eteB-1bs9A:
2.1
3eteD-1bs9A:
2.2
3eteF-1bs9A:
2.1		 3eteB-1bs9A:
18.71
3eteD-1bs9A:
18.71
3eteF-1bs9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 7 ASP A 105
ASP A 153
GLN A 154
PRO A 134
 None
 1.19A 3l2vA-1bs9A:
undetectable		 3l2vA-1bs9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 7 ASP A 105
GLN A 154
PRO A 134
GLU A  94
 None
 0.89A 3l2vA-1bs9A:
undetectable		 3l2vA-1bs9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 7 ALA A 198
VAL A  85
VAL A 202
LEU A 199
 None
 0.78A 3o14A-1bs9A:
0.0		 3o14A-1bs9A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 8 ASP A 105
GLN A 154
PRO A 134
GLU A  94
 None
 0.89A 3oyaA-1bs9A:
undetectable		 3oyaA-1bs9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 7 TYR A  43
ASP A  97
ASP A 133
TYR A  57
 None
 1.09A 3rodD-1bs9A:
1.6		 3rodD-1bs9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 11 VAL A  29
VAL A  87
GLY A   9
ALA A  40
LEU A  30
 None
 1.00A 3sm2B-1bs9A:
undetectable		 3sm2B-1bs9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 10 VAL A  72
ILE A  84
ILE A 167
ALA A  99
VAL A  68
 None
 0.95A 3t3cB-1bs9A:
undetectable		 3t3cB-1bs9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 8 VAL A  68
TYR A  43
GLY A   9
ALA A  99
 None
 0.88A 4m48A-1bs9A:
0.0		 4m48A-1bs9A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 12 ALA A 198
ILE A   5
ILE A 129
VAL A  85
VAL A   7
 None
 0.98A 4nkxA-1bs9A:
undetectable		 4nkxA-1bs9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		5 / 12 SER A  60
GLY A  93
GLY A  92
THR A  13
LEU A  86
 None
 1.08A 4pghD-1bs9A:
undetectable		 4pghD-1bs9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 8 GLY A  88
GLY A  92
GLU A  12
ALA A  45
 None
 0.72A 5vw5A-1bs9A:
undetectable		 5vw5A-1bs9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1bs9 ACETYL XYLAN
ESTERASE
(Talaromyces
purpureogenus) 		4 / 5 TYR A 190
VAL A   7
PHE A 136
GLY A 145
 None
 1.35A 6hd4A-1bs9A:
undetectable		 6hd4A-1bs9A:
18.83