SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bsf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 LYS A  61
ILE A  93
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.91A 1axwA-1bsfA:
32.7		 1axwA-1bsfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 LYS A  61
ILE A  93
LEU A 187
TYR A 224
ALA A 278
 None
 1.11A 1axwA-1bsfA:
32.7		 1axwA-1bsfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 1.13A 1axwB-1bsfA:
33.1		 1axwB-1bsfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ILE A  93
TRP A  94
TRP A  97
GLY A 188
PHE A 191
 None
 1.48A 1axwB-1bsfA:
33.1		 1axwB-1bsfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 11 LYS A  61
ILE A  93
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.83A 1axwB-1bsfA:
33.1		 1axwB-1bsfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.78A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
LEU A 187
GLY A 188
TYR A 224
ALA A 278
 None
 1.07A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
THR A  67
ASP A 184
GLY A 188
TYR A 224
 None
 0.79A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
THR A  67
GLY A 188
TYR A 224
ALA A 278
 None
 1.00A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
THR A  67
ILE A  93
TRP A  97
LEU A 158
 None
 0.99A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 ALA A  64
THR A  67
ILE A  93
TYR A 224
ALA A 278
 None
 0.97A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 THR A  67
ILE A  93
TRP A  94
TRP A  97
LEU A 158
 None
 1.04A 1b02A-1bsfA:
40.7		 1b02A-1bsfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.64A 1hvyA-1bsfA:
31.5		 1hvyA-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.69A 1hvyB-1bsfA:
31.4		 1hvyB-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 GLU A  71
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.57A 1hvyC-1bsfA:
31.6		 1hvyC-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 GLU A  71
ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.97A 1hvyC-1bsfA:
31.6		 1hvyC-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 GLU A  71
ASP A 184
LEU A 187
GLY A 188
PHE A 191
TYR A 224
 None
 0.80A 1hvyD-1bsfA:
31.6		 1hvyD-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ILE A  93
ASP A 184
LEU A 187
TYR A 224
 None
 1.12A 1hvyD-1bsfA:
31.6		 1hvyD-1bsfA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		7 / 9 GLU A  71
ILE A  93
TRP A  94
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.91A 1i00A-1bsfA:
30.1		 1i00A-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 9 ILE A  93
ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.68A 1i00B-1bsfA:
30.4		 1i00B-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 9 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.71A 1ju6B-1bsfA:
31.6		 1ju6B-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.71A 1ju6D-1bsfA:
31.7		 1ju6D-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 10 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.73A 1jujA-1bsfA:
31.8		 1jujA-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 10 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.73A 1jujB-1bsfA:
31.8		 1jujB-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 10 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.73A 1jujC-1bsfA:
31.8		 1jujC-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 10 LYS A  61
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.73A 1jujD-1bsfA:
31.8		 1jujD-1bsfA:
35.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.35A 1rtsA-1bsfA:
31.1		 1rtsA-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.33A 1rtsB-1bsfA:
31.5		 1rtsB-1bsfA:
35.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  12
LEU A 231
THR A  59
LEU A  58
 None
 1.01A 1v54N-1bsfA:
0.0
1v54W-1bsfA:
0.0		 1v54N-1bsfA:
18.60
1v54W-1bsfA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  12
LEU A 231
THR A  59
LEU A  58
 None
 1.00A 2dyrN-1bsfA:
0.0
2dyrW-1bsfA:
0.0		 2dyrN-1bsfA:
18.60
2dyrW-1bsfA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ILE A  12
LEU A 231
THR A  59
LEU A  58
 None
 0.93A 2eikN-1bsfA:
undetectable
2eikW-1bsfA:
undetectable		 2eikN-1bsfA:
18.60
2eikW-1bsfA:
12.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.29A 2tsrA-1bsfA:
31.6		 2tsrA-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.60A 2tsrA-1bsfA:
31.6		 2tsrA-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.42A 2tsrB-1bsfA:
31.1		 2tsrB-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.69A 2tsrB-1bsfA:
31.1		 2tsrB-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 10 GLU A  71
ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.69A 2tsrC-1bsfA:
31.2		 2tsrC-1bsfA:
35.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 9 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.71A 2tsrD-1bsfA:
31.3		 2tsrD-1bsfA:
35.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 TYR A   8
PHE A 275
ILE A  12
ASN A   9
 None
 1.10A 2zseA-1bsfA:
0.0		 2zseA-1bsfA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  12
LEU A 231
THR A  59
LEU A  58
 None
 1.06A 3ablA-1bsfA:
0.0
3ablJ-1bsfA:
0.0		 3ablA-1bsfA:
18.60
3ablJ-1bsfA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 6 PHE A 110
GLY A 105
ALA A 155
LEU A 158
 None
 0.97A 3bgdA-1bsfA:
undetectable		 3bgdA-1bsfA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ALA A  64
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.96A 3nrrA-1bsfA:
0.0		 3nrrA-1bsfA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ALA A  64
GLU A  71
ASP A 184
GLY A 188
TYR A 224
 None
 0.94A 3nrrA-1bsfA:
0.0		 3nrrA-1bsfA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ALA A  64
ASP A 184
LEU A 187
GLY A 188
TYR A 224
 None
 0.99A 3nrrB-1bsfA:
0.0		 3nrrB-1bsfA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ALA A  64
GLU A  71
ASP A 184
GLY A 188
TYR A 224
 None
 0.92A 3nrrB-1bsfA:
0.0		 3nrrB-1bsfA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLN A  47
GLY A 219
GLU A 164
ALA A 180
ASN A 183
 None
 1.31A 3t7sD-1bsfA:
undetectable		 3t7sD-1bsfA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		3 / 3 ASN A 197
LEU A 264
PHE A   4
 None
 0.79A 4dajB-1bsfA:
undetectable		 4dajB-1bsfA:
19.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.56A 4eb4A-1bsfA:
31.0		 4eb4A-1bsfA:
35.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.58A 4eb4B-1bsfA:
31.2		 4eb4B-1bsfA:
35.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 9 ILE A  93
ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.73A 4eb4C-1bsfA:
30.9		 4eb4C-1bsfA:
35.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 10 ILE A  93
ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.72A 4eb4D-1bsfA:
31.2		 4eb4D-1bsfA:
35.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 LYS A  61
ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.87A 4fogD-1bsfA:
32.1		 4fogD-1bsfA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 11 LYS A  61
ILE A  93
ASP A 184
LEU A 187
GLY A 188
 None
 0.90A 4fogD-1bsfA:
32.1		 4fogD-1bsfA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.98A 4foxB-1bsfA:
32.3		 4foxB-1bsfA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 1.03A 4foxD-1bsfA:
32.1		 4foxD-1bsfA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 LYS A  61
GLU A  71
ASP A 184
GLY A 188
TYR A 224
 None
 0.75A 4foxE-1bsfA:
32.0		 4foxE-1bsfA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 7 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.73A 4iqqA-1bsfA:
30.8		 4iqqA-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 7 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.61A 4iqqB-1bsfA:
30.5		 4iqqB-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.35A 4iqqC-1bsfA:
30.4		 4iqqC-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.57A 4iqqC-1bsfA:
30.4		 4iqqC-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 8 LYS A  61
ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 1.08A 4iqqD-1bsfA:
30.6		 4iqqD-1bsfA:
34.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 LEU A 176
VAL A 178
LEU A 131
LEU A 130
 None
 0.91A 4l1xA-1bsfA:
undetectable		 4l1xA-1bsfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 6 LYS A  79
GLY A 109
TYR A 108
ALA A 107
 None
 1.31A 4yshB-1bsfA:
undetectable		 4yshB-1bsfA:
20.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 7 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.65A 5h3aA-1bsfA:
31.2		 5h3aA-1bsfA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 7 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.62A 5h3aB-1bsfA:
31.4		 5h3aB-1bsfA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ILE A  93
TRP A  94
TRP A  97
GLY A 188
 None
 1.01A 5j7wD-1bsfA:
31.9		 5j7wD-1bsfA:
33.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.41A 5nooA-1bsfA:
30.7		 5nooA-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.67A 5nooA-1bsfA:
30.7		 5nooA-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 7 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.56A 5nooB-1bsfA:
30.7		 5nooB-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 6 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.39A 5nooC-1bsfA:
30.2		 5nooC-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 8 ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.58A 5nooD-1bsfA:
30.8		 5nooD-1bsfA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ASP A 184
GLY A 188
PHE A 191
TYR A 224
ALA A 278
 None
 0.96A 5x5qB-1bsfA:
31.7		 5x5qB-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 GLU A  71
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.52A 5x5qB-1bsfA:
31.7		 5x5qB-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 7 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.41A 5x5qC-1bsfA:
31.2		 5x5qC-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.39A 5x5qD-1bsfA:
31.3		 5x5qD-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 6 ILE A  93
ASP A 184
GLY A 188
TYR A 224
 None
 0.77A 5x5qE-1bsfA:
31.2		 5x5qE-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		4 / 8 ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.39A 5x5qF-1bsfA:
31.0		 5x5qF-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 ILE A  93
ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.77A 5x66A-1bsfA:
32.3
5x66B-1bsfA:
32.3		 5x66A-1bsfA:
37.21
5x66B-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 ILE A  93
ASP A 184
LEU A 187
GLY A 188
PHE A 191
ASN A 192
 None
 0.76A 5x66A-1bsfA:
32.3
5x66B-1bsfA:
32.3		 5x66A-1bsfA:
37.21
5x66B-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
GLY A 188
PHE A 191
TYR A 224
ALA A 278
 None
 0.89A 5x66A-1bsfA:
32.3
5x66B-1bsfA:
32.3		 5x66A-1bsfA:
37.21
5x66B-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
LEU A 187
GLY A 188
PHE A 191
ALA A 278
 None
 1.08A 5x66A-1bsfA:
32.3
5x66B-1bsfA:
32.3		 5x66A-1bsfA:
37.21
5x66B-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		7 / 9 ILE A  93
ASP A 184
LEU A 187
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.83A 5x66C-1bsfA:
32.2		 5x66C-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 9 ILE A  93
LEU A 187
GLY A 188
PHE A 191
TYR A 224
ALA A 278
 None
 1.03A 5x66C-1bsfA:
32.2		 5x66C-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 10 ILE A  93
ASP A 184
GLY A 188
PHE A 191
ASN A 192
TYR A 224
 None
 0.78A 5x66D-1bsfA:
32.3		 5x66D-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 10 ILE A  93
GLY A 188
PHE A 191
TYR A 224
ALA A 278
 None
 0.90A 5x66D-1bsfA:
32.3		 5x66D-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 LYS A  61
ILE A  93
ASP A 184
GLY A 188
PHE A 191
TYR A 224
 None
 0.80A 5x66F-1bsfA:
32.1		 5x66F-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 LYS A  61
ILE A  93
ASP A 184
LEU A 187
GLY A 188
PHE A 191
 None
 0.84A 5x66F-1bsfA:
32.1		 5x66F-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 LYS A  61
ILE A  93
GLY A 188
PHE A 191
TYR A 224
ALA A 278
 None
 0.93A 5x66F-1bsfA:
32.1		 5x66F-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		6 / 12 LYS A  61
ILE A  93
LEU A 187
GLY A 188
PHE A 191
ALA A 278
 None
 1.14A 5x66F-1bsfA:
32.1		 5x66F-1bsfA:
37.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
TRP A  94
LEU A 187
GLY A 188
ASN A 192
 None
 1.00A 6qxsB-1bsfA:
30.7		 6qxsB-1bsfA:
33.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
TRP A  94
TRP A  97
GLY A 188
ASN A 192
 None
 0.81A 6qxsB-1bsfA:
30.7		 6qxsB-1bsfA:
33.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
TRP A  94
TRP A  97
GLY A 188
ASN A 192
 None
 0.75A 6qxsD-1bsfA:
30.5		 6qxsD-1bsfA:
33.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1bsf THYMIDYLATE SYNTHASE
A
(Bacillus
subtilis) 		5 / 12 ILE A  93
TRP A  94
TRP A  97
LEU A 158
ASN A 192
 None
 1.01A 6qxsD-1bsfA:
30.5		 6qxsD-1bsfA:
33.03