SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 ARG A  15
ALA A 243
LEU A 247
ILE A 273
PHE A   6
 None
 1.05A 2h77A-1bslA:
undetectable		 2h77A-1bslA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 ARG A  15
ALA A 243
LEU A 247
ILE A 273
PHE A   6
 None
 1.04A 2h79A-1bslA:
0.0		 2h79A-1bslA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		4 / 5 PHE A 125
PHE A 128
PHE A 105
HIS A 132
 None
 1.23A 2lh6A-1bslA:
0.0		 2lh6A-1bslA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PCP_C_1PCC212_1
(IMMUNOGLOBULIN)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 10 HIS A  45
PHE A  10
GLY A  50
TYR A  42
SER A 254
 None
 1.22A 2pcpC-1bslA:
undetectable
2pcpD-1bslA:
undetectable		 2pcpC-1bslA:
21.34
2pcpD-1bslA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		4 / 7 TYR A  42
LEU A 228
LEU A   8
PHE A 250
 None
 1.25A 3nk2X-1bslA:
0.4		 3nk2X-1bslA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		4 / 5 LEU A   5
ALA A  40
MET A  24
ASN A   9
 None
 1.47A 3uq6A-1bslA:
undetectable		 3uq6A-1bslA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 ARG A  15
ALA A 243
LEU A 247
ILE A 273
PHE A   6
 None
 1.07A 4lnwA-1bslA:
0.0		 4lnwA-1bslA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 ARG A  15
ALA A 243
LEU A 247
ILE A 273
PHE A   6
 None
 1.07A 4lnxA-1bslA:
0.0		 4lnxA-1bslA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 ILE A  78
ALA A  54
PHE A 105
HIS A  82
VAL A  86
 None
 1.05A 4rvdA-1bslA:
undetectable		 4rvdA-1bslA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		3 / 3 VAL A 285
LEU A 247
MET A 264
 None
 0.81A 5ikrA-1bslA:
undetectable		 5ikrA-1bslA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		4 / 7 GLU A  89
ASN A   9
ILE A  21
VAL A  58
 None
 0.96A 5jh7C-1bslA:
undetectable		 5jh7C-1bslA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 MET A  24
THR A  27
TYR A  30
ALA A 102
ALA A  40
 None
 1.20A 5kvaA-1bslA:
undetectable		 5kvaA-1bslA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1bsl BACTERIAL LUCIFERASE
(Vibrio
harveyi) 		5 / 12 MET A  24
THR A  27
TYR A  30
ALA A 102
ALA A  40
 None
 1.21A 5kvaB-1bslA:
undetectable		 5kvaB-1bslA:
23.85