SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1bsz PROTEIN (PEPTIDE
DEFORMYLASE)
(Escherichia
coli) 		3 / 3 HIS A 132
ILE A  60
LEU A 125
 FE  A2001 (-3.3A)
None
None
 0.77A 2kceA-1bszA:
0.0		 2kceA-1bszA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 1bsz PROTEIN (PEPTIDE
DEFORMYLASE)
(Escherichia
coli) 		4 / 7 VAL A  16
VAL A 138
GLY A 139
ARG A  56
 None
 0.90A 3bjwC-1bszA:
undetectable		 3bjwC-1bszA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 1bsz PROTEIN (PEPTIDE
DEFORMYLASE)
(Escherichia
coli) 		4 / 8 VAL A  16
VAL A 138
GLY A 139
ARG A  56
 None
 0.95A 3bjwA-1bszA:
undetectable		 3bjwA-1bszA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 1bsz PROTEIN (PEPTIDE
DEFORMYLASE)
(Escherichia
coli) 		3 / 3 HIS A 132
GLU A 133
HIS A 136
 FE  A2001 (-3.3A)
FE  A2001 (-4.2A)
FE  A2001 ( 3.3A)
 0.21A 3kecB-1bszA:
undetectable		 3kecB-1bszA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1bsz PROTEIN (PEPTIDE
DEFORMYLASE)
(Escherichia
coli) 		3 / 3 ASP A  33
VAL A  51
LEU A  46
 None
 0.64A 5e5jB-1bszA:
0.0		 5e5jB-1bszA:
18.01