SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bt0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_C_VD3C2001_1 (VITAMIN D HYDROXYLASE)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	5 / 11	THR A 9 ILE A 13 LEU A 71 ILE A 36 LEU A 43	None	1.27A	3a50C-1bt0A: undetectable	3a50C-1bt0A: 10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5O_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 7	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.85A	4w5oA-1bt0A: undetectable	4w5oA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5Q_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 6	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.80A	4w5qA-1bt0A: undetectable	4w5qA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 6	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.90A	4w5tA-1bt0A: undetectable	4w5tA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 6	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.79A	4z4cA-1bt0A: undetectable	4z4cA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4D_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 6	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.81A	4z4dA-1bt0A: undetectable	4z4dA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4E_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 7	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.84A	4z4eA-1bt0A: undetectable	4z4eA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 7	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.83A	4z4gA-1bt0A: 0.0	4z4gA-1bt0A: 7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CBD_A_TRPA903_0 (PROTEIN ARGONAUTE-2)	1bt0	PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1) (Arabidopsis thaliana)	4 / 6	ILE A 44 GLN A 49 ILE A 23 ASP A 52	None	0.90A	6cbdA-1bt0A: undetectable	6cbdA-1bt0A: 7.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3A50_C_VD3C2001_1","VITAMIN D HYDROXYLASE","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",5,"THR A   9;ILE A  13;LEU A  71;ILE A  36;LEU A  43","None","1.27A","3a50C-1bt0A:undetectable","3a50C-1bt0A:10.50"],["4W5O_A_IPHA904_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.85A","4w5oA-1bt0A:undetectable","4w5oA-1bt0A:7.24"],["4W5Q_A_IPHA902_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.80A","4w5qA-1bt0A:undetectable","4w5qA-1bt0A:7.24"],["4W5T_A_IPHA902_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.90A","4w5tA-1bt0A:undetectable","4w5tA-1bt0A:7.24"],["4Z4C_A_IPHA903_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.79A","4z4cA-1bt0A:undetectable","4z4cA-1bt0A:7.24"],["4Z4D_A_IPHA902_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.81A","4z4dA-1bt0A:undetectable","4z4dA-1bt0A:7.24"],["4Z4E_A_IPHA904_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.84A","4z4eA-1bt0A:undetectable","4z4eA-1bt0A:7.24"],["4Z4G_A_IPHA902_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.83A","4z4gA-1bt0A:0.0","4z4gA-1bt0A:7.24"],["6CBD_A_TRPA903_0","PROTEIN ARGONAUTE-2","1bt0","PROTEIN (UBIQUITIN-LIKE PROTEIN 7, RUB1)","Arabidopsis thaliana",4,"ILE A  44;GLN A  49;ILE A  23;ASP A  52","None","0.90A","6cbdA-1bt0A:undetectable","6cbdA-1bt0A:7.24"]]