SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 8 LEU A 221
ARG A 215
SER A 194
VAL A 238
 None
 1.17A 2qd2A-1bu2A:
undetectable		 2qd2A-1bu2A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 7 ILE A  79
ILE A 198
LEU A 143
LEU A  40
 None
 0.98A 3adxA-1bu2A:
0.0		 3adxA-1bu2A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 5 LEU A  40
ARG A  52
ILE A  79
ARG A  82
 None
 1.48A 3ticA-1bu2A:
undetectable		 3ticA-1bu2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 4 LEU A  80
ILE A  79
GLY A  98
ILE A 104
 None
 0.81A 5dzk3-1bu2A:
undetectable
5dzkm-1bu2A:
undetectable		 5dzk3-1bu2A:
16.67
5dzkm-1bu2A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 5 ILE A  79
GLY A  98
ILE A 104
LEU A  80
 None
 0.85A 5dzkB-1bu2A:
undetectable
5dzkI-1bu2A:
undetectable
5dzkW-1bu2A:
undetectable		 5dzkB-1bu2A:
20.39
5dzkI-1bu2A:
23.27
5dzkW-1bu2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 5 ILE A  79
GLY A  98
ILE A 104
LEU A  80
 None
 0.82A 5dzki-1bu2A:
undetectable
5dzkj-1bu2A:
undetectable
5dzkx-1bu2A:
undetectable		 5dzki-1bu2A:
23.27
5dzkj-1bu2A:
23.27
5dzkx-1bu2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 5 ILE A  79
GLY A  98
ILE A 104
LEU A  80
 None
 0.82A 5dzkd-1bu2A:
undetectable
5dzkk-1bu2A:
0.0
5dzky-1bu2A:
undetectable		 5dzkd-1bu2A:
20.39
5dzkk-1bu2A:
23.27
5dzky-1bu2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		4 / 4 ILE A  79
GLY A  98
ILE A 104
LEU A  80
 None
 0.86A 5dzkl-1bu2A:
undetectable
5dzkz-1bu2A:
undetectable		 5dzkl-1bu2A:
23.27
5dzkz-1bu2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 1bu2 CYCLIN HOMOLOG
(Saimiriine
gammaherpesvirus
2) 		5 / 12 THR A 205
GLY A 201
THR A 206
ALA A 184
ILE A 190
 None
 0.89A 5kb6A-1bu2A:
undetectable		 5kb6A-1bu2A:
20.27