SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 7 VAL A 150
ARG A 187
ILE A  49
TYR A  44
 None
 0.78A 11gsA-1budA:
undetectable		 11gsA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 ALA A  31
VAL A  33
TRP A  32
 None
 0.83A 1bdwA-1budA:
undetectable
1bdwB-1budA:
undetectable		 1bdwA-1budA:
6.43
1bdwB-1budA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.25A 1os2A-1budA:
10.7		 1os2A-1budA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.22A 1os2D-1budA:
10.8		 1os2D-1budA:
23.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		7 / 10 ALA A 106
THR A 107
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.70A 1r55A-1budA:
30.6		 1r55A-1budA:
36.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 6 ALA A 137
LEU A 135
SER A 130
SER A 131
 None
 0.95A 1tz8C-1budA:
undetectable
1tz8D-1budA:
0.0		 1tz8C-1budA:
19.07
1tz8D-1budA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.21A 1uttA-1budA:
11.1		 1uttA-1budA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.28A 1utzA-1budA:
10.9		 1utzA-1budA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.25A 1utzB-1budA:
11.0		 1utzB-1budA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.22A 1y93A-1budA:
11.0		 1y93A-1budA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 8 VAL A 150
ARG A 187
ILE A  49
TYR A  44
 None
 0.78A 2gssA-1budA:
undetectable		 2gssA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 8 VAL A 150
ARG A 187
ILE A  49
TYR A  44
 None
 0.79A 2gssB-1budA:
undetectable		 2gssB-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.19A 2hu6A-1budA:
11.0		 2hu6A-1budA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.36A 2jihA-1budA:
25.0		 2jihA-1budA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 8 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.36A 2jihB-1budA:
25.0		 2jihB-1budA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.31A 2ow9A-1budA:
10.7		 2ow9A-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.30A 2ow9B-1budA:
10.6		 2ow9B-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.33A 2ozrC-1budA:
10.4		 2ozrC-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.35A 2ozrD-1budA:
10.5		 2ozrD-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.33A 2ozrE-1budA:
10.7		 2ozrE-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 HIS A 142
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.25A 2ozrF-1budA:
10.5		 2ozrF-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 7 VAL A 150
ILE A  49
TYR A  44
THR A  41
 None
 1.02A 3gssA-1budA:
undetectable		 3gssA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 7 VAL A 150
ILE A  49
TYR A  44
THR A  41
 None
 0.99A 3gssB-1budA:
undetectable		 3gssB-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.27A 3hy7A-1budA:
25.3		 3hy7A-1budA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.29A 3hy7B-1budA:
25.1		 3hy7B-1budA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 ILE A 138
SER A 171
SER A 169
 None
 0.54A 3iltH-1budA:
undetectable		 3iltH-1budA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.27A 3kecA-1budA:
10.6		 3kecA-1budA:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 HIS A 142
GLU A 143
HIS A 146
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
 0.16A 3kecB-1budA:
10.6		 3kecB-1budA:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.21A 3likA-1budA:
11.0		 3likA-1budA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.22A 3lilA-1budA:
11.1		 3lilA-1budA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 5 ILE A 108
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 1.38A 3ljgA-1budA:
11.2		 3ljgA-1budA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.22A 3lkaA-1budA:
11.0		 3lkaA-1budA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 8 VAL A 150
ARG A 187
ILE A  49
TYR A  44
 None
 0.84A 3n9jA-1budA:
undetectable		 3n9jA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 8 VAL A 150
ARG A 187
ILE A  49
TYR A  44
 None
 0.82A 3n9jB-1budA:
undetectable		 3n9jB-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.38A 4a7bA-1budA:
10.4		 4a7bA-1budA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 8 SER A 115
SER A 122
TYR A 189
ILE A 198
 None
 1.27A 4ms4A-1budA:
4.0		 4ms4A-1budA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.05A 4o2bB-1budA:
undetectable		 4o2bB-1budA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 LEU A  98
LEU A  86
ASN A  94
 None
 0.62A 4otwA-1budA:
undetectable		 4otwA-1budA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.03A 4x1iD-1budA:
undetectable		 4x1iD-1budA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 0.98A 4x1yB-1budA:
undetectable		 4x1yB-1budA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.21A 5n5jA-1budA:
11.0		 5n5jA-1budA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 800 (-3.2A)
ZN  A 800 ( 4.7A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
 0.24A 5n5kA-1budA:
11.1		 5n5kA-1budA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 800 (-3.3A)
ZN  A 800 (-3.3A)
ZN  A 800 (-3.2A)
 0.68A 5x1fN-1budA:
0.0		 5x1fN-1budA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1bud PROTEIN (ACUTOLYSIN
A)
(Deinagkistrodon
acutus) 		4 / 4 HIS A  92
VAL A  13
LEU A  86
ALA A  95
 None
 1.44A 6d8pB-1budA:
0.2		 6d8pB-1budA:
13.17