SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 12 ALA A  77
ALA A  78
LEU A 127
ALA A 123
VAL A 249
 None
 1.06A 1fbyB-1bueA:
undetectable		 1fbyB-1bueA:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 None
 0.40A 1ghmA-1bueA:
37.0		 1ghmA-1bueA:
34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
LYS A 234
GLY A 236
 None
 0.39A 1i2wA-1bueA:
40.2		 1i2wA-1bueA:
41.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
GLY A 236
 None
 0.37A 1i2wB-1bueA:
40.4		 1i2wB-1bueA:
41.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLY A 236
ARG A 220
 None
 1.20A 1i2wB-1bueA:
40.4		 1i2wB-1bueA:
41.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 12 ILE A 138
MET A 122
ALA A 125
ARG A 100
GLU A 140
 None
 1.24A 1ki7B-1bueA:
undetectable		 1ki7B-1bueA:
21.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		9 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
LYS A 234
GLY A 236
 None
 0.63A 1ymxA-1bueA:
41.1		 1ymxA-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
GLY A 239
 None
 0.70A 1ymxA-1bueA:
41.1		 1ymxA-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
 None
 0.62A 1ymxB-1bueA:
41.2		 1ymxB-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
LYS A  73
SER A 130
GLU A 166
ASN A 170
LYS A 234
GLY A 236
SER A 237
 None
 0.75A 1ymxB-1bueA:
41.2		 1ymxB-1bueA:
49.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		3 / 3 LEU A 199
TYR A 207
GLN A 208
 None
 0.72A 2wekA-1bueA:
undetectable		 2wekA-1bueA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 7 PRO A 226
SER A 224
ILE A 287
TRP A 229
 None
 0.92A 2y7kA-1bueA:
undetectable		 2y7kA-1bueA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 7 ARG A  65
GLU A  64
ALA A 185
ALA A 184
 None
 0.94A 2zgwA-1bueA:
undetectable		 2zgwA-1bueA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 8 VAL A 186
LEU A 211
GLY A  74
TYR A 207
 None
 1.00A 3af0A-1bueA:
undetectable		 3af0A-1bueA:
19.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 None
 0.71A 3hlwA-1bueA:
41.0		 3hlwA-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.67A 3hlwB-1bueA:
41.2		 3hlwB-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 239
 None
 0.90A 3hlwB-1bueA:
41.2		 3hlwB-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
 None
 0.70A 3hlwB-1bueA:
41.2		 3hlwB-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.61A 3huoA-1bueA:
41.0		 3huoA-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 6 THR A  51
LEU A 195
GLY A 196
ALA A 257
PRO A 258
 None
 0.25A 3huoA-1bueA:
41.0		 3huoA-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.61A 3huoB-1bueA:
41.0		 3huoB-1bueA:
48.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KDM_B_TESB226_1
(IMMUNOGLOBULIN LIGHT
CHAIN
IMMUNOGLOBULIN HEAVY
CHAIN)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 9 PRO A 107
ALA A 125
TYR A 129
ASP A 121
TYR A 112
 None
 1.44A 3kdmA-1bueA:
0.2
3kdmB-1bueA:
0.0		 3kdmA-1bueA:
20.47
3kdmB-1bueA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
ASN A 132
LEU A 167
THR A 235
GLY A 236
ARG A 220
 None
 0.91A 3mzeA-1bueA:
21.2		 3mzeA-1bueA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
LYS A  73
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 0.75A 3mzeA-1bueA:
21.2		 3mzeA-1bueA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		3 / 3 GLY A  42
ILE A 279
VAL A 278
 None
 0.47A 3nv6A-1bueA:
undetectable		 3nv6A-1bueA:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.57A 3ny4A-1bueA:
38.1		 3ny4A-1bueA:
39.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
 None
 0.91A 3q07A-1bueA:
41.0		 3q07A-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.64A 3q07B-1bueA:
41.0		 3q07B-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 LYS A  73
SER A 130
ASN A 170
LYS A 234
GLY A 236
SER A 237
 None
 0.77A 3q07B-1bueA:
41.0		 3q07B-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 None
 0.54A 3sh8A-1bueA:
39.1		 3sh8A-1bueA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 None
 0.58A 3sh8B-1bueA:
38.6		 3sh8B-1bueA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		10 / 12 LYS A  73
HIS A 105
SER A 130
ASN A 132
LEU A 167
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.26A 4euzA-1bueA:
45.6		 4euzA-1bueA:
60.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 10 SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 None
 0.67A 4fh2A-1bueA:
34.6		 4fh2A-1bueA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.51A 4n9kA-1bueA:
40.2		 4n9kA-1bueA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.52A 4n9kB-1bueA:
40.1		 4n9kB-1bueA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.67A 4pm5A-1bueA:
40.5		 4pm5A-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
 None
 0.72A 4pm5A-1bueA:
40.5		 4pm5A-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.90A 4pm5A-1bueA:
40.5		 4pm5A-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
SER A 237
 None
 0.99A 4pm5A-1bueA:
40.5		 4pm5A-1bueA:
49.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 LYS A  73
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 None
 0.72A 4pm7A-1bueA:
40.5		 4pm7A-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.96A 4pm7A-1bueA:
40.5		 4pm7A-1bueA:
48.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.68A 4pm9A-1bueA:
40.4		 4pm9A-1bueA:
48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.89A 4pm9A-1bueA:
40.4		 4pm9A-1bueA:
48.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 7 ASP A 246
ILE A 221
GLY A 232
THR A 235
 None
 1.15A 4zxiA-1bueA:
undetectable		 4zxiA-1bueA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 7 ALA A  78
ARG A 153
GLY A 156
GLU A 158
 None
 0.76A 5btgA-1bueA:
undetectable
5btgC-1bueA:
0.0
5btgD-1bueA:
undetectable		 5btgA-1bueA:
18.89
5btgC-1bueA:
18.89
5btgD-1bueA:
23.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.54A 5ghyA-1bueA:
40.3		 5ghyA-1bueA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.51A 5ghyB-1bueA:
40.3		 5ghyB-1bueA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 11 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.53A 5ghzA-1bueA:
40.4		 5ghzA-1bueA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 10 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.53A 5ghzB-1bueA:
40.3		 5ghzB-1bueA:
41.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		3 / 3 ALA A 286
ASN A 289
LEU A 290
 None
 0.48A 5i1nC-1bueA:
0.0		 5i1nC-1bueA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 6 PHE A  66
THR A 265
TYR A 264
PHE A  75
 None
 1.26A 5lrbA-1bueA:
undetectable		 5lrbA-1bueA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 8 PRO A 183
ALA A 244
THR A 265
ALA A 286
 None
 0.97A 5x2tI-1bueA:
undetectable
5x2tJ-1bueA:
undetectable
5x2tK-1bueA:
undetectable
5x2tL-1bueA:
undetectable		 5x2tI-1bueA:
17.98
5x2tJ-1bueA:
18.90
5x2tK-1bueA:
17.98
5x2tL-1bueA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 6 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
 1.02A 5yvnA-1bueA:
0.0		 5yvnA-1bueA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.43A 6b5yB-1bueA:
38.5		 6b5yB-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.47A 6b5yD-1bueA:
38.5		 6b5yD-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.31A 6b68B-1bueA:
38.6		 6b68B-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
GLY A 236
 None
 0.37A 6b68D-1bueA:
38.5		 6b68D-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.32A 6b69A-1bueA:
38.2
6b69B-1bueA:
38.5		 6b69A-1bueA:
16.27
6b69B-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.32A 6b69D-1bueA:
38.4		 6b69D-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.38A 6b6aB-1bueA:
38.1		 6b6aB-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.37A 6b6aD-1bueA:
38.0		 6b6aD-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 SER A  70
SER A 130
ASN A 170
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.40A 6b6cA-1bueA:
38.1		 6b6cA-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
 0.35A 6b6dA-1bueA:
38.3		 6b6dA-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.62A 6b6dA-1bueA:
38.3		 6b6dA-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
 None
 0.42A 6b6eA-1bueA:
38.3		 6b6eA-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		7 / 12 CSS A  69
SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.47A 6b6fA-1bueA:
37.9		 6b6fA-1bueA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 6 SER A  59
SER A  56
ALA A 187
ALA A  62
 None
 1.02A 6bocA-1bueA:
undetectable
6bocB-1bueA:
undetectable
6bocC-1bueA:
undetectable
6bocD-1bueA:
undetectable		 6bocA-1bueA:
5.66
6bocB-1bueA:
5.66
6bocC-1bueA:
5.66
6bocD-1bueA:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		5 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
GLY A 239
 None
 0.83A 6c79A-1bueA:
41.2		 6c79A-1bueA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 None
 0.64A 6c79A-1bueA:
41.2		 6c79A-1bueA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		6 / 12 SER A 130
ASN A 170
THR A 216
LYS A 234
GLY A 236
SER A 237
 None
 0.78A 6c79A-1bueA:
41.2		 6c79A-1bueA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 8 LEU A 119
LEU A  89
LEU A 139
GLY A 144
 None
 0.79A 6ce2A-1bueA:
undetectable		 6ce2A-1bueA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)
(Enterobacter
cloacae) 		4 / 6 LEU A 139
THR A 135
GLY A 133
ARG A 100
 None
 1.10A 6gtqB-1bueA:
0.0
6gtqD-1bueA:
undetectable		 6gtqB-1bueA:
20.82
6gtqD-1bueA:
9.54