SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 NA  A 121 (-4.4A)
None
NA  A 121 (-2.6A)
None
None
 0.76A 1th6A-1bunA:
17.3		 1th6A-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 NA  A 121 (-4.4A)
None
NA  A 121 (-2.6A)
None
None
 0.76A 2armA-1bunA:
17.3		 2armA-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  63
LYS A  64
 None
NA  A 121 (-2.6A)
None
None
None
 0.56A 2armA-1bunA:
17.3		 2armA-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
PHE A 101
 None
None
NA  A 121 (-4.4A)
NA  A 122 (-4.5A)
None
 0.55A 2azyA-1bunA:
17.4		 2azyA-1bunA:
45.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
TYR A 106
 None
None
NA  A 121 (-4.4A)
NA  A 122 (-4.5A)
None
 0.58A 2azyA-1bunA:
17.4		 2azyA-1bunA:
45.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		3 / 3 ASP A  49
TYR A  52
LYS A  64
 NA  A 121 (-2.6A)
None
None
 0.67A 2othA-1bunA:
17.3		 2othA-1bunA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		4 / 8 LYS A   1
HIS A  48
ASP A  94
ALA A  55
 None
 1.38A 2rk8A-1bunA:
2.1		 2rk8A-1bunA:
11.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		4 / 7 LEU A   2
TRP A  19
ALA A  23
GLY A  30
 None
None
None
NA  A 121 (-4.4A)
 0.72A 2wq5A-1bunA:
20.1		 2wq5A-1bunA:
53.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 121 (-2.6A)
None
None
 0.53A 3fo7A-1bunA:
17.2		 3fo7A-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 121 (-2.6A)
None
None
 0.52A 3h1xA-1bunA:
17.3		 3h1xA-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		4 / 5 PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
None
NA  A 121 (-4.4A)
None
 0.71A 3r0lD-1bunA:
18.9		 3r0lD-1bunA:
42.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		5 / 9 VAL A  47
ALA A  97
PHE A 101
TYR A 106
TYR A  25
 None
 1.46A 4lb2B-1bunA:
2.1		 4lb2B-1bunA:
10.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		6 / 12 GLY A  30
GLY A  32
TYR A  52
ASN A  62
PRO A  63
LYS A  64
 NA  A 121 (-4.4A)
NA  A 121 (-3.8A)
None
None
None
None
 1.00A 6ce2B-1bunA:
16.4		 6ce2B-1bunA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1bun BETA2-BUNGAROTOXIN
(Bungarus
multicinctus) 		6 / 12 LEU A   2
GLY A  32
TYR A  52
ASN A  62
PRO A  63
LYS A  64
 None
NA  A 121 (-3.8A)
None
None
None
None
 0.93A 6ce2B-1bunA:
16.4		 6ce2B-1bunA:
37.30