SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1buy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		4 / 8 THR A 163
GLY A 158
THR A 157
ALA A 160
 None
 0.85A 2a1hA-1buyA:
undetectable
2a1hB-1buyA:
undetectable		 2a1hA-1buyA:
17.60
2a1hB-1buyA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		4 / 8 THR A 163
GLY A 158
THR A 157
ALA A 160
 None
 0.84A 2a1hA-1buyA:
undetectable
2a1hB-1buyA:
undetectable		 2a1hA-1buyA:
17.60
2a1hB-1buyA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		3 / 3 LEU A   5
ARG A 162
ILE A   6
 None
 0.64A 2xn5B-1buyA:
undetectable		 2xn5B-1buyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		3 / 3 SER A 120
GLU A  62
ASP A  43
 None
 0.60A 2zulA-1buyA:
undetectable		 2zulA-1buyA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		3 / 3 SER A 120
GLU A  62
ASP A  43
 None
 0.62A 3dmhA-1buyA:
undetectable		 3dmhA-1buyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		4 / 5 TYR A 145
PRO A  42
THR A  40
THR A  26
 None
 1.36A 3q07A-1buyA:
undetectable		 3q07A-1buyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		4 / 5 TYR A 145
PRO A  42
THR A  40
THR A  26
 None
 1.38A 3q07B-1buyA:
undetectable		 3q07B-1buyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 1buy PROTEIN
(ERYTHROPOIETIN)
(Homo
sapiens) 		5 / 12 LEU A 112
ALA A 118
SER A 120
GLY A  66
LEU A  67
 None
 0.77A 6b0cD-1buyA:
undetectable		 6b0cD-1buyA:
15.76