SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bvl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		4 / 5 ARG B  24
ALA B  25
ASP B  70
GLY B  68
 None
 1.19A 1e7cA-1bvlB:
undetectable		 1e7cA-1bvlB:
10.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		7 / 12 TYR B  36
GLN B  89
PHE B  98
ASN A  35
VAL A  37
ALA A  96
TRP A 106
 None
 0.67A 1h8sA-1bvlB:
21.3		 1h8sA-1bvlB:
59.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG B  96
THR A  57
TRP A  52
 None
 1.25A 4d7hA-1bvlB:
undetectable		 4d7hA-1bvlB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG B  96
THR A  57
TRP A  52
 None
 1.24A 4uglA-1bvlB:
undetectable		 4uglA-1bvlB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		4 / 6 MET A  50
TRP A  47
LEU A 103
ALA A  96
 None
 1.15A 6fosB-1bvlA:
undetectable		 6fosB-1bvlA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		5 / 12 THR A  86
VAL A 114
VAL A 112
VAL A  67
TYR A  93
 None
 1.47A 6iblA-1bvlA:
undetectable		 6iblA-1bvlA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 1bvl HULYS11
(Homo
sapiens;
Mus
musculus) 		5 / 12 THR A  86
VAL A 114
VAL A 112
VAL A  67
TYR A  93
 None
 1.48A 6iblB-1bvlA:
undetectable		 6iblB-1bvlA:
15.26