SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 8 ALA A  94
LEU A  98
ALA A 344
THR A 348
 None
 0.92A 1ie4B-1bvuA:
undetectable
1ie4D-1bvuA:
undetectable		 1ie4B-1bvuA:
16.71
1ie4D-1bvuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 8 GLY A  55
VAL A 107
GLU A  77
ILE A  41
 None
 0.70A 1pk7B-1bvuA:
undetectable		 1pk7B-1bvuA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 10 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.08A 1pxxA-1bvuA:
0.0		 1pxxA-1bvuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 9 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.07A 1pxxB-1bvuA:
undetectable		 1pxxB-1bvuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.09A 1pxxC-1bvuA:
0.0		 1pxxC-1bvuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 10 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.08A 1pxxD-1bvuA:
0.0		 1pxxD-1bvuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		3 / 3 PRO A 143
THR A 174
PRO A 141
 None
 0.80A 2d55C-1bvuA:
undetectable		 2d55C-1bvuA:
3.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 8 TYR A 137
ASP A 167
TYR A 131
TYR A 159
 None
 1.43A 2ha2A-1bvuA:
3.6		 2ha2A-1bvuA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 8 TYR A 137
ASP A 167
TYR A 131
TYR A 159
 None
 1.40A 2ha2B-1bvuA:
undetectable		 2ha2B-1bvuA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		3 / 3 ASP A 339
ASN A 343
THR A 348
 None
 0.71A 2q63B-1bvuA:
0.0		 2q63B-1bvuA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 6 ILE A 130
PRO A  33
LEU A  79
ILE A  36
 None
 0.97A 2q83B-1bvuA:
0.0		 2q83B-1bvuA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8F_A_DM1A127_1
(TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 10 MET A 376
ALA A 379
VAL A 383
ALA A 402
VAL A 347
 None
 1.10A 3f8fA-1bvuA:
0.0
3f8fB-1bvuA:
0.0		 3f8fA-1bvuA:
15.20
3f8fB-1bvuA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 ASP A 326
VAL A 313
ALA A 314
PHE A 340
THR A 321
 None
 1.23A 3n23A-1bvuA:
0.0		 3n23A-1bvuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 ASP A 326
LEU A 329
VAL A 313
PHE A 340
THR A 321
 None
 1.13A 3n23C-1bvuA:
undetectable		 3n23C-1bvuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 ASP A 326
VAL A 313
ALA A 314
PHE A 340
THR A 321
 None
 1.23A 3n23C-1bvuA:
undetectable		 3n23C-1bvuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 GLY A 218
ALA A 295
ILE A 216
ALA A 227
ASP A 243
 None
 1.18A 3nmuB-1bvuA:
0.0
3nmuJ-1bvuA:
3.3		 3nmuB-1bvuA:
21.37
3nmuJ-1bvuA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		3 / 3 GLY A 101
THR A  90
ASN A  61
 None
 0.70A 3v4tD-1bvuA:
0.0		 3v4tD-1bvuA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A 401
ILE A 312
ILE A 337
LEU A 341
VAL A  95
 None
 1.15A 3w68C-1bvuA:
undetectable		 3w68C-1bvuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.01A 4coxA-1bvuA:
undetectable		 4coxA-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.02A 4coxB-1bvuA:
1.0		 4coxB-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.03A 4coxD-1bvuA:
undetectable		 4coxD-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 GLY A 346
ALA A 344
ALA A 194
ASP A 188
VAL A 349
 None
 0.99A 4df3A-1bvuA:
3.9		 4df3A-1bvuA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 GLY A 346
ALA A 344
ALA A 194
ASP A 188
VAL A 349
 None
 1.00A 4df3B-1bvuA:
4.0		 4df3B-1bvuA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.01A 4otyA-1bvuA:
0.9		 4otyA-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.01A 4otyB-1bvuA:
undetectable		 4otyB-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.01A 4rrxA-1bvuA:
undetectable		 4rrxA-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 TYR A 225
LEU A 372
GLY A 193
ALA A 194
LEU A 316
 None
 1.11A 4rrxB-1bvuA:
undetectable		 4rrxB-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 1.02A 4rrxB-1bvuA:
undetectable		 4rrxB-1bvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 GLY A  69
ILE A 358
ASN A 357
ASP A 139
PRO A  66
 None
 1.22A 4rtrA-1bvuA:
undetectable		 4rtrA-1bvuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 GLY A  69
ILE A 358
ASN A 357
ASP A 139
PRO A  66
 None
 1.22A 4rtsA-1bvuA:
0.3		 4rtsA-1bvuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 LEU A 316
SER A 294
ILE A 216
VAL A 241
 None
 1.02A 4tvtA-1bvuA:
0.0		 4tvtA-1bvuA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		3 / 3 MET A 114
GLU A 118
LEU A 122
 None
 0.54A 4v2oB-1bvuA:
0.0		 4v2oB-1bvuA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		3 / 3 GLU A 285
LYS A 309
ASN A 304
 None
 1.09A 4y1dA-1bvuA:
0.0
4y1dD-1bvuA:
undetectable		 4y1dA-1bvuA:
19.57
4y1dD-1bvuA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 VAL A  95
LEU A 372
GLY A 345
ALA A 344
 None
 0.91A 5f1aB-1bvuA:
undetectable		 5f1aB-1bvuA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 9 LEU A 122
ILE A 151
ILE A 108
PHE A  53
VAL A  52
 None
 1.47A 5igzA-1bvuA:
undetectable		 5igzA-1bvuA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 0.98A 5ikqA-1bvuA:
undetectable		 5ikqA-1bvuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 0.96A 5ikqB-1bvuA:
undetectable		 5ikqB-1bvuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 12 VAL A  95
LEU A 372
VAL A 347
GLY A 345
ALA A 344
 None
 0.98A 5iktA-1bvuA:
0.0		 5iktA-1bvuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 10 THR A 197
ALA A 379
ALA A 194
GLY A 193
ALA A 344
 None
 1.13A 5lf3H-1bvuA:
undetectable
5lf3I-1bvuA:
undetectable		 5lf3H-1bvuA:
20.43
5lf3I-1bvuA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 10 THR A 197
ALA A 379
ALA A 194
GLY A 193
ALA A 344
 None
 1.11A 5lf3V-1bvuA:
undetectable
5lf3W-1bvuA:
undetectable		 5lf3V-1bvuA:
20.43
5lf3W-1bvuA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 THR A 197
ALA A 379
ALA A 194
GLY A 193
ALA A 344
 None
 1.13A 5lf7H-1bvuA:
undetectable
5lf7I-1bvuA:
undetectable		 5lf7H-1bvuA:
20.43
5lf7I-1bvuA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		5 / 11 THR A 197
ALA A 379
ALA A 194
GLY A 193
ALA A 344
 None
 1.12A 5lf7V-1bvuA:
undetectable
5lf7W-1bvuA:
undetectable		 5lf7V-1bvuA:
20.43
5lf7W-1bvuA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 8 ALA A  86
THR A  90
THR A  93
ALA A 409
 None
 0.93A 5x2tI-1bvuA:
undetectable
5x2tJ-1bvuA:
undetectable
5x2tK-1bvuA:
undetectable
5x2tL-1bvuA:
undetectable		 5x2tI-1bvuA:
16.39
5x2tJ-1bvuA:
16.79
5x2tK-1bvuA:
16.39
5x2tL-1bvuA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 LEU A  30
LEU A  13
ALA A  16
ALA A  17
 None
 0.69A 6a7jA-1bvuA:
undetectable		 6a7jA-1bvuA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 ILE A 308
LEU A 284
ILE A 337
ALA A 295
 None
 0.82A 6b5vA-1bvuA:
0.0
6b5vC-1bvuA:
0.0		 6b5vA-1bvuA:
10.05
6b5vC-1bvuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 ALA A 295
ILE A 308
LEU A 284
ILE A 337
 None
 0.79A 6b5vA-1bvuA:
0.0
6b5vB-1bvuA:
0.0		 6b5vA-1bvuA:
10.05
6b5vB-1bvuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 ILE A 308
LEU A 284
ILE A 337
ALA A 295
 None
 0.84A 6b5vC-1bvuA:
0.0
6b5vD-1bvuA:
0.0		 6b5vC-1bvuA:
10.05
6b5vD-1bvuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1bvu PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermococcus
litoralis) 		4 / 7 ALA A 295
ILE A 308
LEU A 284
ILE A 337
 None
 0.83A 6b5vB-1bvuA:
0.0
6b5vD-1bvuA:
0.0		 6b5vB-1bvuA:
10.05
6b5vD-1bvuA:
10.05