SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bvw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 12 PHE A 439
LEU A 443
PHE A 379
ALA A 128
HIS A 110
 None
None
None
None
MAN  A 650 (-4.6A)
 1.32A 1a4lB-1bvwA:
5.1		 1a4lB-1bvwA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		4 / 7 LEU A 255
LEU A 228
LEU A 304
GLY A 303
 None
 0.84A 1n13D-1bvwA:
0.0
1n13E-1bvwA:
0.0		 1n13D-1bvwA:
14.05
1n13E-1bvwA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		3 / 3 SER A 107
THR A 151
GLN A 136
 None
 0.81A 2fk8A-1bvwA:
undetectable		 2fk8A-1bvwA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 12 ASP A 175
ARG A 140
THR A 143
ILE A 171
GLU A 224
 None
 1.21A 2yzqA-1bvwA:
undetectable		 2yzqA-1bvwA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 8 THR A 219
LEU A 221
VAL A 173
LEU A 152
VAL A 144
 None
 1.26A 2zujA-1bvwA:
0.0		 2zujA-1bvwA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 12 THR A 306
GLY A 270
GLY A 303
ASN A 307
LEU A 275
 None
 1.19A 3eeyD-1bvwA:
undetectable		 3eeyD-1bvwA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		4 / 7 GLY A 401
GLY A 402
TYR A 438
ASN A 373
 None
 1.05A 4fgkB-1bvwA:
undetectable		 4fgkB-1bvwA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 12 LEU A 228
PHE A 347
VAL A 301
GLY A 303
LEU A 255
 None
 1.10A 4ot2A-1bvwA:
undetectable		 4ot2A-1bvwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 12 LEU A 148
LEU A 138
ILE A 207
ILE A 204
MET A 265
 None
 0.88A 4y0rA-1bvwA:
0.0		 4y0rA-1bvwA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		4 / 6 ASP A 354
ASP A 180
ASN A 230
ASN A 310
 None
 1.27A 5l6eA-1bvwA:
undetectable		 5l6eA-1bvwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_A_CP6A704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 10 ALA A 169
HIS A 262
PHE A 214
VAL A 149
THR A 219
 None
 1.38A 6aogA-1bvwA:
undetectable		 6aogA-1bvwA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_B_CP6B704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		5 / 10 ALA A 169
HIS A 262
PHE A 214
VAL A 149
THR A 219
 None
 1.38A 6aogB-1bvwA:
undetectable		 6aogB-1bvwA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1bvw PROTEIN
(CELLOBIOHYDROLASE
II)
(Humicola
insolens) 		3 / 3 THR A 233
GLU A 286
ASN A 280
 None
 0.59A 6nj9K-1bvwA:
undetectable		 6nj9K-1bvwA:
19.16