SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 ILE F 585
GLY F 568
VAL F 566
ALA F 605
GLY F 487
 None
None
None
FMN  F1002 ( 4.8A)
None
 0.92A 1kiaA-1bvyF:
undetectable		 1kiaA-1bvyF:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 ILE F 585
GLY F 568
VAL F 566
ALA F 605
GLY F 487
 None
None
None
FMN  F1002 ( 4.8A)
None
 0.90A 1kiaB-1bvyF:
undetectable		 1kiaB-1bvyF:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 ILE F 585
GLY F 568
VAL F 566
ALA F 605
GLY F 487
 None
None
None
FMN  F1002 ( 4.8A)
None
 0.91A 1kiaC-1bvyF:
undetectable		 1kiaC-1bvyF:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 ILE F 585
GLY F 568
VAL F 566
ALA F 605
GLY F 487
 None
None
None
FMN  F1002 ( 4.8A)
None
 0.93A 1nbhB-1bvyF:
undetectable		 1nbhB-1bvyF:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 8 VAL F 581
GLY F 491
THR F 492
ALA F 493
 None
FMN  F1002 (-3.9A)
FMN  F1002 (-3.7A)
FMN  F1002 (-3.4A)
 0.81A 2a1hA-1bvyF:
undetectable
2a1hB-1bvyF:
undetectable		 2a1hA-1bvyF:
19.40
2a1hB-1bvyF:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 8 SER F 565
ASN F 596
ILE F 597
ASP F 623
 None
 1.11A 2v57A-1bvyF:
undetectable		 2v57A-1bvyF:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 8 SER F 565
ASN F 596
ILE F 597
ASP F 623
 None
 1.11A 2v57C-1bvyF:
undetectable		 2v57C-1bvyF:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		3 / 3 PHE F 628
ASN F 629
PHE F 509
 None
 0.88A 2zbuD-1bvyF:
2.7		 2zbuD-1bvyF:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 VAL F 562
LEU F 523
TRP F 550
PHE F 547
ILE F 585
 None
 1.26A 3kk6B-1bvyF:
undetectable		 3kk6B-1bvyF:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 10 LEU F 483
ALA F 501
ASP F 502
ILE F 503
GLY F 495
 None
 0.96A 3ogqA-1bvyF:
undetectable		 3ogqA-1bvyF:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 LEU F 483
ALA F 501
ASP F 502
ILE F 503
GLY F 495
 None
 0.95A 3ogqB-1bvyF:
undetectable		 3ogqB-1bvyF:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 7 ASN F 543
ALA F 544
PRO F 541
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 1.09A 3twpA-1bvyF:
undetectable		 3twpA-1bvyF:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 7 ASN F 543
ALA F 544
PRO F 541
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 1.10A 3twpB-1bvyF:
undetectable		 3twpB-1bvyF:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 7 ASN F 543
ALA F 544
PRO F 541
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 1.12A 3twpC-1bvyF:
undetectable		 3twpC-1bvyF:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 5 ASN F 543
ALA F 544
PRO F 541
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 1.09A 3twpD-1bvyF:
1.5		 3twpD-1bvyF:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 8 ASN F 543
PHE F 547
VAL F 548
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 0.94A 4eyzA-1bvyF:
undetectable		 4eyzA-1bvyF:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 8 ASN F 543
PHE F 547
VAL F 548
ALA F 493
 None
None
None
FMN  F1002 (-3.4A)
 0.95A 4eyzB-1bvyF:
undetectable		 4eyzB-1bvyF:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		4 / 4 TYR F 564
THR F 588
VAL F 559
ILE F 531
 None
 1.28A 4jx1F-1bvyF:
0.0		 4jx1F-1bvyF:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1bvy PROTEIN (CYTOCHROME
P450 BM-3)
(Bacillus
megaterium) 		5 / 12 LEU F 516
ASP F 586
ALA F 497
VAL F 529
TYR F 564
 None
 1.17A 5kbwB-1bvyF:
undetectable		 5kbwB-1bvyF:
24.55