SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bwd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 CYH A 105
HIS A 102
GLY A 327
GLY A 328
 None
 0.81A 1ekjA-1bwdA:
undetectable
1ekjB-1bwdA:
undetectable		 1ekjA-1bwdA:
19.05
1ekjB-1bwdA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 LEU A 156
ARG A  31
LEU A 171
ALA A  35
 None
 0.83A 1fiqC-1bwdA:
undetectable		 1fiqC-1bwdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 5 LEU A 124
CYH A 105
ALA A 333
CYH A 332
 None
 1.00A 1mz9D-1bwdA:
0.0		 1mz9D-1bwdA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		3 / 3 THR A  61
LEU A  65
LEU A  72
 None
 0.58A 1mz9C-1bwdA:
undetectable		 1mz9C-1bwdA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 12 LEU A 287
ASN A 286
GLY A 284
GLN A 301
THR A 334
 None
 1.41A 1p93A-1bwdA:
undetectable		 1p93A-1bwdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 7 GLU A 140
TYR A 141
LEU A 137
THR A  78
 None
 1.23A 1rmtB-1bwdA:
undetectable		 1rmtB-1bwdA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 THR A 334
LEU A 318
VAL A  79
VAL A  16
 None
 0.91A 1t86A-1bwdA:
0.0		 1t86A-1bwdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 5 PRO A 121
GLY A 198
ASN A 199
GLY A 202
 None
 0.82A 1zlqA-1bwdA:
0.0		 1zlqA-1bwdA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 9 LEU A 137
LEU A 138
ILE A 117
LEU A 335
ILE A  17
 None
 1.17A 2f78A-1bwdA:
undetectable		 2f78A-1bwdA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 9 LEU A 137
LEU A 138
ILE A 117
LEU A 335
ILE A  17
 None
 1.18A 2f78B-1bwdA:
undetectable		 2f78B-1bwdA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 9 LEU A 137
LEU A 138
ILE A 117
LEU A 335
ILE A  17
 None
 1.16A 2f7aA-1bwdA:
undetectable		 2f7aA-1bwdA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 9 LEU A 137
LEU A 138
ILE A 117
LEU A 335
ILE A  17
 None
 1.21A 2f7aB-1bwdA:
undetectable		 2f7aB-1bwdA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 8 ARG A 339
ALA A  69
GLY A  19
ILE A  17
LEU A 288
 None
 1.48A 2o4nB-1bwdA:
undetectable		 2o4nB-1bwdA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 TYR A 134
HIS A 102
HIS A  87
ARG A  85
 None
 1.31A 2vmyA-1bwdA:
undetectable
2vmyB-1bwdA:
undetectable		 2vmyA-1bwdA:
21.41
2vmyB-1bwdA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 12 SER A 323
LEU A 320
HIS A 322
THR A  61
TYR A 104
 None
 1.47A 3mbhE-1bwdA:
undetectable		 3mbhE-1bwdA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 11 SER A 323
LEU A 320
HIS A 322
THR A  61
TYR A 104
 None
 1.47A 3mbhF-1bwdA:
undetectable		 3mbhF-1bwdA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 TYR A  53
HIS A 278
LEU A 124
MET A 122
 None
 1.24A 3uzzB-1bwdA:
undetectable		 3uzzB-1bwdA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 6 PRO A 317
LEU A 294
ASN A 314
GLU A 309
 None
 1.03A 3zqtA-1bwdA:
0.0		 3zqtA-1bwdA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 7 THR A 334
LEU A 318
VAL A  79
VAL A  16
 None
 0.90A 4cp4A-1bwdA:
undetectable		 4cp4A-1bwdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 11 GLN A 301
ILE A 270
GLY A 329
GLY A 328
TYR A 104
 None
 1.39A 4fglA-1bwdA:
undetectable
4fglB-1bwdA:
undetectable		 4fglA-1bwdA:
23.94
4fglB-1bwdA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 5 LEU A 335
PRO A 106
LEU A 110
ILE A 117
 None
 0.76A 4klrA-1bwdA:
undetectable		 4klrA-1bwdA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 THR A 116
VAL A 216
LEU A 190
GLY A 114
 None
 0.91A 4r3aA-1bwdA:
undetectable		 4r3aA-1bwdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 11 ALA A  69
LEU A  72
GLU A  15
LEU A  13
LEU A 288
 None
 1.12A 4wg0K-1bwdA:
undetectable
4wg0L-1bwdA:
undetectable
4wg0M-1bwdA:
undetectable		 4wg0K-1bwdA:
2.97
4wg0L-1bwdA:
2.97
4wg0M-1bwdA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 6 SER A 245
ASP A 269
ARG A 324
GLY A 284
 None
 0.80A 5cdnA-1bwdA:
0.0
5cdnB-1bwdA:
undetectable		 5cdnA-1bwdA:
23.06
5cdnB-1bwdA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 6 ALA A 333
THR A 334
VAL A  18
VAL A 296
 None
 1.00A 5eckA-1bwdA:
0.7		 5eckA-1bwdA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 6 ALA A 333
THR A 334
VAL A  18
VAL A 296
 None
 0.79A 5eclA-1bwdA:
0.0		 5eclA-1bwdA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 ALA A 333
THR A 334
VAL A  18
VAL A 296
 None
 0.80A 5ecnD-1bwdA:
0.0		 5ecnD-1bwdA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		5 / 8 GLY A  76
LEU A  75
VAL A 296
VAL A  16
LEU A 316
 None
 1.45A 6czmD-1bwdA:
0.0
6czmF-1bwdA:
0.0		 6czmD-1bwdA:
23.26
6czmF-1bwdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 8 ASP A  86
ARG A  85
ASP A 103
GLU A 130
 None
 1.22A 6mn4A-1bwdA:
0.0		 6mn4A-1bwdA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		4 / 7 HIS A 217
THR A 215
ARG A 257
ASP A 254
 None
 1.36A 6mn4E-1bwdA:
0.0		 6mn4E-1bwdA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)
(Streptomyces
griseus) 		3 / 3 ILE A  17
THR A 334
PRO A  82
 None
 0.62A 6ncsA-1bwdA:
undetectable		 6ncsA-1bwdA:
22.04