SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 6 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.20A 1nsiA-1bwyA:
0.0
1nsiB-1bwyA:
0.0		 1nsiA-1bwyA:
16.24
1nsiB-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 6 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.22A 1nsiA-1bwyA:
0.0
1nsiB-1bwyA:
0.0		 1nsiA-1bwyA:
16.24
1nsiB-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 6 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.23A 1nsiC-1bwyA:
0.0
1nsiD-1bwyA:
0.0		 1nsiC-1bwyA:
16.24
1nsiD-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 6 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.19A 1nsiC-1bwyA:
0.0
1nsiD-1bwyA:
0.0		 1nsiC-1bwyA:
16.24
1nsiD-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		5 / 10 TYR A  19
GLY A 120
THR A 121
ALA A 122
VAL A  25
 None
 1.42A 2coiA-1bwyA:
undetectable
2coiB-1bwyA:
undetectable		 2coiA-1bwyA:
18.90
2coiB-1bwyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		5 / 10 VAL A  25
TYR A  19
GLY A 120
THR A 121
ALA A 122
 None
 1.40A 2coiA-1bwyA:
undetectable
2coiB-1bwyA:
undetectable		 2coiA-1bwyA:
18.90
2coiB-1bwyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		5 / 11 LEU A  23
VAL A  80
HIS A  93
THR A  73
THR A  74
 None
 1.09A 2dttD-1bwyA:
undetectable
2dttE-1bwyA:
undetectable		 2dttD-1bwyA:
21.13
2dttE-1bwyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.17A 2nsiA-1bwyA:
0.0
2nsiB-1bwyA:
0.0		 2nsiA-1bwyA:
16.24
2nsiB-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.17A 2nsiA-1bwyA:
0.0
2nsiB-1bwyA:
0.0		 2nsiA-1bwyA:
16.24
2nsiB-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.18A 2nsiC-1bwyA:
0.0
2nsiD-1bwyA:
undetectable		 2nsiC-1bwyA:
16.24
2nsiD-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.18A 2nsiC-1bwyA:
0.0
2nsiD-1bwyA:
undetectable		 2nsiC-1bwyA:
16.24
2nsiD-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.19A 3e7gA-1bwyA:
undetectable
3e7gB-1bwyA:
undetectable		 3e7gA-1bwyA:
15.70
3e7gB-1bwyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.21A 3e7gA-1bwyA:
undetectable
3e7gB-1bwyA:
undetectable		 3e7gA-1bwyA:
15.70
3e7gB-1bwyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.16A 3e7gC-1bwyA:
undetectable
3e7gD-1bwyA:
undetectable		 3e7gC-1bwyA:
15.70
3e7gD-1bwyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 8 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.22A 3e7gC-1bwyA:
undetectable
3e7gD-1bwyA:
undetectable		 3e7gC-1bwyA:
15.70
3e7gD-1bwyA:
15.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 PHE A  70
ASP A  77
ILE A  51
VAL A  49
 None
 1.10A 3p6hA-1bwyA:
19.2		 3p6hA-1bwyA:
64.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 8 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.18A 4cx7A-1bwyA:
undetectable
4cx7B-1bwyA:
undetectable		 4cx7A-1bwyA:
16.24
4cx7B-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 8 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.15A 4cx7A-1bwyA:
undetectable
4cx7B-1bwyA:
undetectable		 4cx7A-1bwyA:
16.24
4cx7B-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 8 ARG A 106
ILE A  50
PHE A  64
GLU A  72
 None
 1.22A 4cx7C-1bwyA:
0.0
4cx7D-1bwyA:
0.0		 4cx7C-1bwyA:
16.24
4cx7D-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 7 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.15A 4cx7C-1bwyA:
0.0
4cx7D-1bwyA:
0.0		 4cx7C-1bwyA:
16.24
4cx7D-1bwyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		4 / 6 PHE A  64
GLU A  72
ARG A 106
ILE A  50
 None
 1.31A 4nosC-1bwyA:
0.0
4nosD-1bwyA:
0.0		 4nosC-1bwyA:
15.26
4nosD-1bwyA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		3 / 3 THR A  53
HIS A 119
LEU A 117
 None
 0.85A 5axdC-1bwyA:
0.0		 5axdC-1bwyA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)
(Bos
taurus) 		5 / 12 PHE A  57
SER A  55
GLY A  33
VAL A  32
THR A  29
 None
 1.08A 5o4yD-1bwyA:
undetectable
5o4yE-1bwyA:
0.0		 5o4yD-1bwyA:
9.52
5o4yE-1bwyA:
24.82