SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		4 / 5 LEU A 247
GLY A 119
ALA A 221
ILE A 249
 None
 0.76A 2aohB-1bwzA:
0.0		 2aohB-1bwzA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		4 / 8 GLY A 210
VAL A 206
GLU A 208
TYR A 207
 None
 0.91A 4fgzA-1bwzA:
undetectable		 4fgzA-1bwzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		4 / 8 GLY A 210
VAL A 206
GLU A 208
TYR A 207
 None
 0.88A 4fgzB-1bwzA:
undetectable		 4fgzB-1bwzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		5 / 12 THR A  29
PHE A  25
LEU A  33
ILE A 267
PHE A   3
 None
 1.39A 5dlvA-1bwzA:
undetectable		 5dlvA-1bwzA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		5 / 12 THR A  29
PHE A  25
LEU A  33
ILE A 267
PHE A   3
 None
 1.39A 5dlvB-1bwzA:
undetectable		 5dlvB-1bwzA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		5 / 12 ALA A  81
VAL A  97
GLY A  74
LEU A 242
LEU A 247
 None
 1.32A 5x23A-1bwzA:
0.0		 5x23A-1bwzA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		4 / 8 ILE A  62
PHE A  25
LEU A  33
ALA A  34
 None
 0.76A 5y7pC-1bwzA:
0.0		 5y7pC-1bwzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		3 / 3 ALA A  77
PHE A  13
GLN A  44
 None
 0.81A 6eceA-1bwzA:
undetectable		 6eceA-1bwzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1bwz PROTEIN
(DIAMINOPIMELATE
EPIMERASE)
(Haemophilus
influenzae) 		5 / 12 VAL A  48
ILE A  47
ILE A  30
TYR A 268
ILE A 267
 None
 1.12A 6mkeA-1bwzA:
undetectable
6mkeD-1bwzA:
undetectable		 6mkeA-1bwzA:
13.38
6mkeD-1bwzA:
13.38